Chlamydia trachomatis as the Cause of Infectious Infertility: Acute, Repetitive or Persistent Long-Term Infection?

Author(s):  
Larissa Schuchardt ◽  
Jan Rupp
2013 ◽  
Vol 1 (2) ◽  
pp. 80
Author(s):  
Dewa Nyoman Wirawan ◽  
Emily Rowe ◽  
Fonny Silfanus ◽  
Putri Pidari ◽  
Gusti Ayu Satriani ◽  
...  

Abstract: The objective of this study is to analyze the long-term trends of Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) infections and risk factors among female sex workers (FSW) in Denpasar, Bali, Indonesia. In order to understand the long-term trends, secondary data was examined from the years 1997-1999, 2004, 2007, 2009 and 2010; to analyze associated factors, data from 2010 was used.  Analysis indicates an overall decrease of NG prevalence in Bali from 60.5% (95%CI: 56.6-64.5) in 1997 to 22% (95%CI: 16.8-27.1) in 2010. CT prevalence has also experienced a long term decline but not to the same degree as NG. Findings from analysis of surveys in 2004 and 2010 indicate that there is a strong relationship between condom use in the last sexual transaction with NG infection (p=0.02), duration of sex work (p=0.02), number of clients in the last week (p=0.01), clinic visit intervals and clinic visit frequency. CT prevalence was associated with the number of clients (p=0.04) and clinic visit frequency. Unfortunately, these were the only variables collected therefore a multivariate analysis was not possible. High prevalence of both GN and CT is associated with the high mobility of FSW and low condom use. There is a significant long-term decrease of NG prevalence from 60.5% to 22%. However, CT experienced an insignificant long term decrease from 41.3% to 35%.


1998 ◽  
Vol 9 (3) ◽  
pp. 162-163
Author(s):  
M Huengsberg ◽  
D Mullis ◽  
J Gray ◽  
R S Sawers ◽  
K W Radcliffe

Inadequate treatment and follow-up of women with genital infection with Chlamydia trachomatis and Neisseria gonorrhoeae can cause long-term morbidity1,2. Inadequate contact tracing can predispose to re-infection3. As some women with genital infections present to agencies other than genitourinary medicine (GUM) clinics, improved liaison between these and GUM departments are important in safeguarding proper follow-up and contact tracing4.


2019 ◽  
Vol 24 (42) ◽  
Author(s):  
Tone Bjordal Johansen ◽  
Hilde Kløvstad ◽  
Rikard Rykkvin ◽  
Einar Bredo Herrfurth-Erichsen ◽  
Joakim Sorthe ◽  
...  

The ‘Finnish new variant of Chlamydia trachomatis’ (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT variants (CT 23S rRNA C1514T and G1523A) also escaped AC2 detection. The high FI-nvCT proportion might indicate a long-term national spread and it cannot be excluded that FI-nvCT emerged in Norway.


2016 ◽  
Vol 10 (02) ◽  
pp. 134-137 ◽  
Author(s):  
Danielle M Brasiliense ◽  
Bárbara N Borges ◽  
Wallax A S Ferreira

Introduction: Genital Chlamydia trachomatis infection is one of the most prevalent sexually transmitted diseases in women, and undetected cases of the disease are highly associated with long-term complications. Despite the high prevalence of infections in Brazil, very little is known about the distribution of C. trachomatis genovars. In this study, we determined the prevalence and genotypes of C. trachomatis in women treated at a public hospital in the Brazilian city of Belém, the capital of the state of Pará. Methodology: A total of 154 women were tested for chlamydial infection by PCR using specific primers for the C. trachomatis cryptic plasmid. Genotyping of positive samples was performed by sequencing the ompA gene and conducting further phylogenetic analysis. Results: Out of the 154 samples, 17 were found to be positive using C. trachomatis cryptic plasmid PCR. The overall prevalence of C. trachomatis infection was 11%, with the highest prevalence observed in women between 16 and 20 years of age. Five genotypes were found to be associated with endocervical infection. Genotype F was most frequently found (37.5%), followed by genotypes J (25%), E (25%), I (6.25%), and D (6.25%). Conclusions: This study emphasizes the relevance of C. trachomatis infection in the young female population of the Brazilian Amazon region. It also demonstrates the diversity of genotypes involved in genital infection in this population.


2019 ◽  
Vol 60 (1) ◽  
pp. 149-153 ◽  
Author(s):  
Suzanne Marie Garland ◽  
Asvini Kokila Subasinghe ◽  
Navera Ahmed ◽  
Yasmin Jayasinghe ◽  
Alex Marceglia

2020 ◽  
Vol 148 ◽  
Author(s):  
R. X. Weng ◽  
H. L. Fu ◽  
C. L. Zhang ◽  
J. B. Ye ◽  
F. C. Hong ◽  
...  

Abstract Chlamydia trachomatis (CT) infection has been a major public health threat globally. Monitoring and prediction of CT epidemic status and trends are important for programme planning, allocating resources and assessing impact; however, such activities are limited in China. In this study, we aimed to apply a seasonal autoregressive integrated moving average (SARIMA) model to predict the incidence of CT infection in Shenzhen city, China. The monthly incidence of CT between January 2008 and June 2019 in Shenzhen was used to fit and validate the SARIMA model. A seasonal fluctuation and a slightly increasing pattern of a long-term trend were revealed in the time series of CT incidence. The monthly CT incidence ranged from 4.80/100 000 to 21.56/100 000. The mean absolute percentage error value of the optimal model was 8.08%. The SARIMA model could be applied to effectively predict the short-term CT incidence in Shenzhen and provide support for the development of interventions for disease control and prevention.


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