Manipulation of the Host Cell Cytoskeleton by Chlamydia

2016 ◽  
pp. 59-80 ◽  
Author(s):  
Ana T. Nogueira ◽  
Antonio T. Pedrosa ◽  
Rey A. Carabeo
Keyword(s):  
Host Cell ◽  
Cell Cytoskeleton

Apicomplexans pulling the strings: manipulation of the host cell cytoskeleton dynamics

Parasitology ◽  
2016 ◽  
Vol 143 (8) ◽  
pp. 957-970 ◽  
Author(s):  
RITA CARDOSO ◽  
HELENA SOARES ◽  
ANDREW HEMPHILL ◽  
ALEXANDRE LEITÃO
Keyword(s):  
Host Cell ◽  
Life Cycle Stage ◽  
Effector Proteins ◽  
Cell Physiology ◽  
Apicomplexan Parasites ◽  
Cell Cytoskeleton ◽  
Cytoskeletal Filament ◽  
Associated Proteins ◽  
Organelle Trafficking ◽  
Cytoskeleton Dynamics

SUMMARYInvasive stages of apicomplexan parasites require a host cell to survive, proliferate and advance to the next life cycle stage. Once invasion is achieved, apicomplexans interact closely with the host cell cytoskeleton, but in many cases the different species have evolved distinct mechanisms and pathways to modulate the structural organization of cytoskeletal filaments. The host cell cytoskeleton is a complex network, largely, but not exclusively, composed of microtubules, actin microfilaments and intermediate filaments, all of which are modulated by associated proteins, and it is involved in diverse functions including maintenance of cell morphology and mechanical support, migration, signal transduction, nutrient uptake, membrane and organelle trafficking and cell division. The ability of apicomplexans to modulate the cytoskeleton to their own advantage is clearly beneficial. We here review different aspects of the interactions of apicomplexans with the three main cytoskeletal filament types, provide information on the currently known parasite effector proteins and respective host cell targets involved, and how these interactions modulate the host cell physiology. Some of these findings could provide novel targets that could be exploited for the development of preventive and/or therapeutic strategies.

Do pathogenic neisseriae need several ways to modify the host cell cytoskeleton?

2000 ◽  
Vol 2 (7) ◽  
pp. 821-827 ◽  
Author(s):  
Céline Pujol ◽  
Emmanuel Eugène ◽  
Philippe Morand ◽  
Xavier Nassif
Keyword(s):  
Host Cell ◽  
Cell Cytoskeleton

scholarly journals Plasmodium falciparum Plasmodiumhelical interspersed subtelomeric proteins contribute to cytoadherence and anchorP. falciparumerythrocyte membrane protein 1 to the host cell cytoskeleton

2016 ◽  
Vol 18 (10) ◽  
pp. 1415-1428 ◽  
Author(s):  
Alexander Oberli ◽  
Laura Zurbrügg ◽  
Sebastian Rusch ◽  
Françoise Brand ◽  
Madeleine E. Butler ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Membrane Protein ◽  
Host Cell ◽  
Cell Cytoskeleton

scholarly journals Pixuna virus modifies host cell cytoskeleton to secure infection

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Pedro Ignacio Gil ◽  
Guillermo Albrieu-Llinás ◽  
Estela Cecilia Mlewski ◽  
Marina Monetti ◽  
Laura Fozzatti ◽  
...  
Keyword(s):  
Host Cell ◽  
Cell Cytoskeleton

scholarly journals Perturbation of Host Cell Cytoskeleton by Cranberry Proanthocyanidins and Their Effect on Enteric Infections

PLoS ONE ◽  
2011 ◽  
Vol 6 (11) ◽  
pp. e27267 ◽  
Author(s):  
Kevin Harmidy ◽  
Nathalie Tufenkji ◽  
Samantha Gruenheid
Keyword(s):  
Host Cell ◽  
Cell Cytoskeleton ◽  
Enteric Infections

Bacterial Manipulation of the Host Cell Cytoskeleton

2014 ◽  
pp. 275-297
Author(s):  
Jennifer R. Robbins ◽  
David N. Baldwin ◽  
Sandra J. McCallum ◽  
Julie A. Theriot
Keyword(s):  
Host Cell ◽  
Cell Cytoskeleton
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