Intradermal Rabies Vaccination: The Evolution and Future of Pre- and Post-exposure Prophylaxis

2011 ◽  
pp. 139-157 ◽  
Author(s):  
M. J. Warrell
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Paralytic rabies: An acute flaccid myelitis after inadequate post exposure prophylaxis

2019 ◽  
Vol 49 (4) ◽  
pp. 301-302
Author(s):  
Ashok Kumar Pannu ◽  
Raichur Vijay Kumar ◽  
Deeksha Vijaykumar ◽  
Lakshmi Priya ◽  
Harpreet Singh ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Middle Aged ◽  
Post Exposure ◽  
Acute Flaccid Myelitis ◽  
Clinical Syndromes ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Rabies has two distinct clinical syndromes, encephalitic (or ‘furious’) and paralytic (or ‘dumb’). The paralytic form presents as acute flaccid myelitis and is more common in patients who received post-exposure anti-rabies vaccination without rabies immunoglobulins. We have recently had the opportunity to manage a middle-aged man presenting as ‘dumb’ paralytic rabies.

scholarly journals Safety and immunogenicity of intradermal rabies vaccination for post exposure prophylaxis

2016 ◽  
pp. 692-696
Author(s):  
Ravish Hardanahalli ◽  
Rachana Annadani ◽  
Madhusudana Shampur ◽  
Veena Vijayashankar ◽  
Ashwath Doddabele ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

scholarly journals Compliance to anti-rabies vaccination in post-exposure prophylaxis

2015 ◽  
Vol 59 (1) ◽  
pp. 58 ◽  
Author(s):  
RavishHaradanahalli Shankaraiah ◽  
RachanaAnnadani Rajashekar ◽  
Vijayashankar Veena ◽  
Ashwath NarayanaDoddabele Hanumanthaiah
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Immunogenic response in obese patients undergoing rabies post-exposure prophylaxis with combined equine rabies immunoglobulin and rabies vaccination

Vaccine ◽  
2018 ◽  
Vol 36 (2) ◽  
pp. 285-291 ◽  
Author(s):  
Jatuporn Sirikun ◽  
Yupin Suputtamongkol ◽  
Ploypailin Rattanachinakorn ◽  
Athiwat Primsirikunawut
Keyword(s):  
Post Exposure Prophylaxis ◽  
Obese Patients ◽  
Post Exposure ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination ◽  
Immunogenic Response

scholarly journals A Case of Serious Adverse Reaction Following Rabies Vaccination

2018 ◽  
Vol 5 ◽  
pp. 2333794X1881714 ◽  
Author(s):  
Zhilin Kang ◽  
Wen Chin Chiang ◽  
Si Hui Goh ◽  
Anne Eng Neo Goh ◽  
Peter Choong Yi Wong ◽  
...  
Keyword(s):  
Adverse Reaction ◽  
Rabies Vaccine ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Close Observation ◽  
Stray Dog ◽  
Multiple Challenges ◽  
Graded Challenge ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Introduction. Rabies is one of the most deadly infectious disease. We present a challenging case of an adverse reaction following rabies vaccine in a child. Case Summary. A 10-year-old girl was bitten by a stray dog in Bali and was prescribed rabies post-exposure prophylaxis. She developed breathlessness, abdominal cramps, and lips and eyes swelling 30 minutes after the second dose of rabies vaccine. The subsequent vaccine was successfully administered as a graded challenge with premedication. The final dose was administered in entirety under close observation. She developed transient hypotension 30 minutes later, which spontaneously resolved. Conclusion. There were multiple challenges in the care of this pediatric patient who was potentially exposed to rabies and experienced systemic adverse events during the course of post-exposure prophylaxis. A thorough clinical assessment should be made to weigh benefits versus risks of proceeding with rabies vaccination, bearing in mind that the disease is deadly.

scholarly journals Post exposure compliance of rabies vaccination among cases attending anti-rabies clinic at tertiary care centre, Rajasthan

2019 ◽  
Vol 6 (4) ◽  
pp. 1618
Author(s):  
Dilip Raj ◽  
Mahendra Kumar Verma ◽  
Dharmesh Kumar Sharma ◽  
Sudhakar Sharma ◽  
Munmun Yadav
Keyword(s):  
Compliance Rate ◽  
Tertiary Care ◽  
Red Cross ◽  
Post Exposure Prophylaxis ◽  
Tertiary Care Centre ◽  
Long Distance ◽  
Post Exposure ◽  
Number Of Patients ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Background: Rabies is one of the deadliest diseases of mankind, and has terrified since antiquity. It is 100 per cent fatal, however, 100% preventable. In India, rabies causes an estimated 20,565 deaths with 17.4 million exposures to animal bites, mainly dog bites, occurring every year. In India a person is bitten by an animal in every 2 seconds and someone dies from rabies every 30 second. Complete post-exposure prophylaxis is necessary among the animal bite cases for complete protection. Hence this study aims to determine the patient’s compliance for intradermal anti-rabies vaccination and also to determine the constraints for compliance.Methods: A retrospective record based study was conducted in the ARC of S.M.S.M.C, Jaipur where patients were provided intradermal rabies vaccination (updated Thai Red Cross regimen) for post-exposure prophylaxis. The records maintained at ARC-SMSMC under department of community medicine from March 2016- February 2017 were analysed. The total number of patients was 8873 from which 8590 subjects were recruited for the study after excluding category I cases, pre-exposure cases rat bite, human bite, re-exposure and pre-exposure cases. The major constraints were found out by interviewing the patient/guardian through the telephone.Results: The compliance rate for intradermal rabies vaccination (IDRV) is 81.87%. The major constraints were timings not convenient, personal or social workload, long distance from the hospital, forgotten the dates.Conclusions: The compliance rate for rabies vaccination is considerably low for this highly fatal disease. Considering these major constraint factors, the animal bite victims should be motivated effectively through health education at the time of initiation of vaccination course to attain the goal of rabies free India.

scholarly journals Evaluation of dog anti rabies vaccination centres and post exposure prophylaxis against rabies centres in an urban area

2018 ◽  
Vol 5 (4) ◽  
pp. 1535
Author(s):  
Rambadan P. Chauhan
Keyword(s):  
Urban Area ◽  
Animal Husbandry ◽  
Health Department ◽  
Post Exposure Prophylaxis ◽  
Voluntary Organizations ◽  
Public Health Department ◽  
Post Exposure ◽  
Rabies Exposure ◽  
Exposure Prophylaxis ◽  
Rabies Vaccination

Background: In spite of availability of vaccine, many rabies cases continue to occur. Is this due to the improper functioning of vaccination centres? Objective of the study was to evaluate the performance of dog anti rabies vaccination centres, for vaccination of pet dogs (DARVCs) and post exposure prophylaxis against rabies (PtEPAR) centres for humans for suspected rabies exposure in an urban area.Methods: The study was carried out during 1989-90, by way of observations, interviews and analysis of records maintained at various institutes. For observations procedures like dog licensing, dog vaccination, dog catching in fields, keeping them in kennels and their destruction, human post exposure prophylaxis against rabies viz. history taking by a physician, his advice to patients, procedure of vaccination and local wound care.Results: All (9) MCGB (Municipal Corporation of greater Bombay) run DARVCs and one (25%) DAHD (district animal husbandry department, Bombay suburbs) run DARVC had unsatisfactory services. Three (75%) DAHD run DARVCs and all three voluntary organizations run DARVCs (100%) had satisfactory services. The practices at PtEPAR centres and the knowledge of the doctors appointed there were dismally poor for post exposure prophylaxis against rabies. Only 2 (5.88%) PtEPAR centres were fit to provide PtEPAR services.Conclusions: Significant findings included poor dog anti-rabies vaccination services involving negligible number of dogs every year, dismally poor performances by the human post exposure prophylaxis against rabies centres, lack of pre-exposure prophylaxis to high risk individuals, ignorance on the part of physicians and pathologists regarding availability of rabies diagnostic services in this urban area, poor surveillance by public health department and lack of co-ordination among various institutes.

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