DNA Vaccines and Intradermal Vaccination by DNA Tattooing

2010 ◽  
pp. 221-250 ◽  
Author(s):  
K. Oosterhuis ◽  
J. H. van den Berg ◽  
T. N. Schumacher ◽  
J. B. A. G. Haanen
Keyword(s):  
Dna Vaccines ◽  
Intradermal Vaccination

Sucrose and Facilitated Tucking for Pain Among Neonates Receiving Vaccination, in Puducherry

2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Sujatha S. ◽  
Rebecca Samson ◽  
Christopher Amalraj ◽  
Sundaresan Sundaresan
Keyword(s):  
Sucrose Solution ◽  
Study Groups ◽  
Primary Outcome Measure ◽  
Intradermal Injection ◽  
Control Group ◽  
Intradermal Vaccination ◽  
Term Neonates ◽  
Bcg Vaccination ◽  
Pharmacologic Agents ◽  
Study Intervention

Neglected pain in neonates leads to various ill effects and it can be prevented by using simple and safe non-pharmacological pain relieving measures. Pharmacologic agents are not recommended in neonates for acute pain due toinvasive procedures however, administration of 24% oralsucrose solutionis found to be effective. The objective of this study was to assess the efficacy of 24%oral sucrose in combination with Facilitated tucking during BCG Vaccination through intradermalroute in term neonates which is not done elsewhere. Fifty five healthy term neonates who fulfilled the inclusion criteria such as gestational age above 37 weeks, within 24 hoursof birth age, and neonates delivered only through spontaneous vaginal delivery were included in the study. The study intervention consists of administration of 2 ml of oral 24% sucrose 2 minutes before BCG Vaccination through intradermal route and Facilitated tuckingat the time of vaccination. The primary outcome measure of cumulative NIPS score at 0, 3,5 minuteswas not significant in both the study groups. Whereas there was significant reduction in the level of pain and mean cry time in the neonates of sucrose group. Heart rateand oxygen saturation after intradermal injection also showed significant (p less than 0.001) differenceamong the neonates, who received 24% of oral sucroseand Facilitated tucking than for neonates of control group. Thus oral (24%)sucrose solution given 2 minutes before injection was effective in reducing level of neonatal pain following Intradermal Vaccination. It is a simple, safe and fast acting analgesic and should be considered for minor invasive procedures in term neonates which last for 5-7minutes.

Enhanced Efficacy of DNA Vaccines Against an Intracellular Bacterial Pathogen by Genetic Adjuvants

2003 ◽  
Vol 4 (2) ◽  
pp. 99-107 ◽  
Author(s):  
Sophie Leclercq ◽  
Jerome Harms ◽  
Sergio Oliveira
Keyword(s):  
Dna Vaccines ◽  
Bacterial Pathogen

Plasmids Encoding Protein Aggregation Domains Act As Molecular Adjuvants for DNA Vaccines

2014 ◽  
Vol 14 (3) ◽  
pp. 161-169 ◽  
Author(s):  
Melamia Capitani ◽  
Fadi Saade ◽  
Kristina Havas ◽  
Mauro Angeletti ◽  
Fabio Concetti ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Dna Vaccines ◽  
Encoding Protein ◽  
Molecular Adjuvants

DNA Vaccines for Prostate Cancer

2012 ◽  
Vol 8 (4) ◽  
pp. 245-253
Author(s):  
Douglas G. McNeel ◽  
Jordan T. Becker ◽  
Laura E. Johnson ◽  
Brian M. Olson
Keyword(s):  
Prostate Cancer ◽  
Dna Vaccines

DNA Vaccines

2003 ◽  
Author(s):  
Hildegund C. J. Ertl
Keyword(s):  
Dna Vaccines

scholarly journals Sub-100 nm chitosan-triphosphate-DNA nanoparticles for delivery of DNA vaccines

2020 ◽  
Author(s):  
RENATO NUNES ◽  
Ângela Sousa ◽  
Aiva Simaite ◽  
Ahmed Aido ◽  
Matej Buzgo
Keyword(s):  
Dna Vaccines ◽  
Dna Nanoparticles
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