Understanding the Murine Cutaneous Dendritic Cell Network to Improve Intradermal Vaccination Strategies

2010 ◽  
pp. 1-24 ◽  
Author(s):  
F. Ginhoux ◽  
L. G. Ng ◽  
M. Merad
Keyword(s):  
Dendritic Cell ◽  
Intradermal Vaccination ◽  
Cell Network ◽  
Vaccination Strategies

scholarly journals Dendritic Cell-Based and Other Vaccination Strategies for Pediatric Cancer

Cancers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1396 ◽  
Author(s):  
Sévérine de Bruijn ◽  
Sébastien Anguille ◽  
Joris Verlooy ◽  
Evelien L. Smits ◽  
Viggo F. van Tendeloo ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Pediatric Cancer ◽  
Cancer Vaccines ◽  
Pediatric Population ◽  
Cancer Recurrence ◽  
Western World ◽  
Cancer Treatments ◽  
Vaccination Strategies ◽  
Vulnerable Patient ◽  
Therapeutic Cancer Vaccines

Dendritic cell-based and other vaccination strategies that use the patient’s own immune system for the treatment of cancer are gaining momentum. Most studies of therapeutic cancer vaccination have been performed in adults. However, since cancer is one of the leading causes of death among children past infancy in the Western world, the hope is that this form of active specific immunotherapy can play an important role in the pediatric population as well. Since children have more vigorous and adaptable immune systems than adults, therapeutic cancer vaccines are expected to have a better chance of creating protective immunity and preventing cancer recurrence in pediatric patients. Moreover, in contrast to conventional cancer treatments such as chemotherapy, therapeutic cancer vaccines are designed to specifically target tumor cells and not healthy cells or tissues. This reduces the likelihood of side effects, which is an important asset in this vulnerable patient population. In this review, we present an overview of the different therapeutic cancer vaccines that have been studied in the pediatric population, with a main focus on dendritic cell-based strategies. In addition, new approaches that are currently being investigated in clinical trials are discussed to provide guidance for further improvement and optimization of pediatric cancer vaccines.

Transcriptional programming of the dendritic cell network

2012 ◽  
Vol 12 (2) ◽  
pp. 101-113 ◽  
Author(s):  
Gabrielle T. Belz ◽  
Stephen L. Nutt
Keyword(s):  
Dendritic Cell ◽  
Cell Network

The Epididymal Dendritic Cell Network Is Affected by Efferent Duct Ligation and Vasectomy.

2011 ◽  
Vol 85 (Suppl_1) ◽  
pp. 43-43 ◽  
Author(s):  
Nicolas Da Silva ◽  
Eric Hill ◽  
Sylvie Breton
Keyword(s):  
Dendritic Cell ◽  
Efferent Duct ◽  
Cell Network ◽  
Duct Ligation

scholarly journals Natural Killer Cells: The Secret Weapon in Dendritic Cell Vaccination Strategies

2014 ◽  
Vol 20 (5) ◽  
pp. 1095-1103 ◽  
Author(s):  
Catharina H.M.J. Van Elssen ◽  
Tammy Oth ◽  
Wilfred T.V. Germeraad ◽  
Gerard M.J. Bos ◽  
Joris Vanderlocht
Keyword(s):  
Dendritic Cell ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Dendritic Cell Vaccination ◽  
Killer Cells ◽  
Vaccination Strategies

scholarly journals The Origin of Skin Dendritic Cell Network and Its Role in Psoriasis

2017 ◽  
Vol 19 (1) ◽  
pp. 42 ◽  
Author(s):  
Tae-Gyun Kim ◽  
Sung Kim ◽  
Min-Geol Lee
Keyword(s):  
Dendritic Cell ◽  
Cell Network

scholarly journals Erratum: Transcriptional programming of the dendritic cell network

2013 ◽  
Vol 13 (2) ◽  
pp. 149-149
Author(s):  
Gabrielle T. Belz ◽  
Stephen L. Nutt
Keyword(s):  
Dendritic Cell ◽  
Cell Network

scholarly journals Found in translation: the human equivalent of mouse CD8+ dendritic cells

2010 ◽  
Vol 207 (6) ◽  
pp. 1131-1134 ◽  
Author(s):  
Jose A. Villadangos ◽  
Ken Shortman
Keyword(s):  
Dendritic Cells ◽  
Dendritic Cell ◽  
Cross Presentation ◽  
Cell Network

The murine dendritic cell network comprises multiple subsets with distinct functions, but few of their human counterparts have been described. New data now reveals the likely human equivalent of the mouse DC subset specialized in cross-presentation.

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