scholarly journals Ethical Issues Associated with the Use of Animal Experimentation in Behavioral Neuroscience Research

Author(s):  
Frauke Ohl ◽  
Franck Meijboom
2010 ◽  
Vol 25 (2) ◽  
pp. 205-210 ◽  
Author(s):  
Jamie N Labuzetta ◽  
Rowan Burnstein ◽  
John Pickard

Methods ◽  
2006 ◽  
Vol 38 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Adriaan M. Karssen ◽  
Jun Z. Li ◽  
Song Her ◽  
Paresh D. Patel ◽  
Fan Meng ◽  
...  

Author(s):  
Helton Maia Peixoto ◽  
Richardson Santiago Teles ◽  
John Victor Alves Luiz ◽  
Aron Miranda Henriques-Alves ◽  
Rossana Moreno Santa Cruz

The development of computational tools is essential for the development of new technologies, including experimental designs needed for behavioral neuroscience research. The computational tool developed in this study is based on the convolutional neural networks and the You Only Look Once (YOLO) algorithm for detecting and tracking mice in videos recorded during behavioral neuroscience experiments. The task of mice detection consists of determining the location in the image where the animals are present, for each frame acquired. In this work, we propose mice tracking using the YOLO algorithm, running on an NVIDIA GeForce GTX 1060 GPU. We analyzed a set of data composed of 13622 images, made up of behavioral videos of three important researches in this area. The training set used 50% of the images, 25% for validation and 25% for the tests. The results show that the mean Average Precision (mAP) reached by the developed system was 90.79% and 90.75% for the Full and Tiny versions of YOLO, respectively. It has also been found that the use of the Tiny version is a good alternative for experimental designs that require real-time response. Considering the high accuracy of the results, the developed work allows the experimentalists to perform mice tracking in a reliable and non-evasive way, avoiding common system errors that require delimitations of regions of interest (ROI) or even evasive luminous identifiers such as LED for tracking the animals.


ILAR Journal ◽  
2021 ◽  
Author(s):  
Adam J Shriver ◽  
Tyler M John

Abstract Growing awareness of the ethical implications of neuroscience in the early years of the 21st century led to the emergence of the new academic field of “neuroethics,” which studies the ethical implications of developments in the neurosciences. However, despite the acceleration and evolution of neuroscience research on nonhuman animals, the unique ethical issues connected with neuroscience research involving nonhuman animals remain underdiscussed. This is a significant oversight given the central place of animal models in neuroscience. To respond to these concerns, the Center for Neuroscience and Society and the Center for the Interaction of Animals and Society at the University of Pennsylvania hosted a workshop on the “Neuroethics of Animal Research” in Philadelphia, Pennsylvania. At the workshop, expert speakers and attendees discussed ethical issues arising from neuroscience research involving nonhuman animals, including the use of animal models in the study of pain and psychiatric conditions, animal brain-machine interfaces, animal–animal chimeras, cerebral organoids, and the relevance of neuroscience to debates about personhood. This paper highlights important emerging ethical issues based on the discussions at the workshop. This paper includes recommendations for research in the United States from the authors based on the discussions at the workshop, loosely following the format of the 2 Gray Matters reports on neuroethics published by the Presidential Commission for the Study of Bioethical Issues.


2007 ◽  
Vol 4 (3) ◽  
pp. 537-544 ◽  
Author(s):  
Perry D. Cohen ◽  
Linda Herman ◽  
Sheryl Jedlinski ◽  
Peggy Willocks ◽  
Paula Wittekind

2004 ◽  
Vol 5 (2) ◽  
pp. 162-164
Author(s):  
Matilde Leonardi ◽  
Elena Colombetti ◽  
Alessio Musio ◽  
Stefania Radaelli ◽  
Adriano Pessina

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