scholarly journals Preparation of Decellularized Liver Scaffolds and Recellularized Liver Grafts

2017 ◽  
pp. 255-270 ◽  
Author(s):  
Yibin Chen ◽  
Sharon Geerts ◽  
Maria Jaramillo ◽  
Basak E. Uygun
Keyword(s):  
Decellularized Liver

scholarly journals Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold

2019 ◽  
Vol 10 ◽  
pp. 127-133 ◽  
Author(s):  
Takahito Minami ◽  
Takamichi Ishii ◽  
Kentaro Yasuchika ◽  
Ken Fukumitsu ◽  
Satoshi Ogiso ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Three Dimensional ◽  
Artificial Liver ◽  
Induced Pluripotent ◽  
Decellularized Liver

Decellularized liver transplant could be recellularized in rat partial hepatectomy model

2019 ◽  
Vol 107 (11) ◽  
pp. 2576-2588 ◽  
Author(s):  
Erfani M. Naeem ◽  
Daneshi Sajad ◽  
Tahereh Talaei‐Khozani ◽  
Sahar Khajeh ◽  
Negar Azarpira ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Partial Hepatectomy ◽  
Decellularized Liver

Pre-coating decellularized liver with HepG2-conditioned medium improves hepatic recellularization

2021 ◽  
pp. 111862
Author(s):  
Luiz Carlos Caires-Júnior ◽  
Ernesto Goulart ◽  
Kayque Alves Telles-Silva ◽  
Bruno Henrique Silva Araujo ◽  
Camila Manso Musso ◽  
...  
Keyword(s):  
Conditioned Medium ◽  
Decellularized Liver

Decellularized liver-regenerative 3D printing biomaterials for cell-based liver therapies via a designed procedure combined with papain-containing reagent treatments and supercritical fluids

2021 ◽  
pp. 1-8
Author(s):  
Ching-Cheng Huang
Keyword(s):  
3D Printing ◽  
Thermo Gravimetric Analysis ◽  
Extraction Process ◽  
Gravimetric Analysis ◽  
Collagen Scaffolds ◽  
Scanning Calorimetry ◽  
Porcine Liver ◽  
Good Thermal Stability ◽  
Decellularized Liver ◽  
Liver Collagen

BACKGROUND: The biologic scaffolds derived from decellularized tissues and organs have been successfully developed in a variety of preclinical and/or clinical studies. OBJECTIVE: The new decellularized liver-regenerative 3D printing biomaterials were designed and prepared for cell-based liver therapies. METHODS: An extraction process was employed to remove the tissue and cellular molecules from porcine liver via pretreatment of supercritical fluid of carbon dioxide (ScCO2). Varying porosities of the decellularized liver tissues were created using papain-containing reagent treatments after ScCO2. RESULTS: The resulting liver-regenerative 3D printing biomaterials of decellularized liver collagen scaffolds were characterized by Fourier transform infrared spectroscopy, thermo-gravimetric analysis, differential scanning calorimetry and scanning electron microscopy. CONCLUSIONS: The decellularized liver collagen scaffolds with good thermal stability (>150 °C) were obtained and employed as liver-regenerative 3D printing biomaterials for cell-based liver therapies.

Construction of sinusoid-scale microvessels in perfusion culture of a decellularized liver

2019 ◽  
Vol 95 ◽  
pp. 307-318 ◽  
Author(s):  
Masafumi Watanabe ◽  
Koki Yano ◽  
Koki Okawa ◽  
Tadahiro Yamashita ◽  
Kazuki Tajima ◽  
...  
Keyword(s):  
Perfusion Culture ◽  
Decellularized Liver

Scale-dependent mechanical properties of native and decellularized liver tissue

2012 ◽  
Vol 12 (3) ◽  
pp. 569-580 ◽  
Author(s):  
Douglas W. Evans ◽  
Emma C. Moran ◽  
Pedro M. Baptista ◽  
Shay Soker ◽  
Jessica L. Sparks
Keyword(s):  
Mechanical Properties ◽  
Liver Tissue ◽  
Decellularized Liver

Sympathetic neurotransmitters promote the process of recellularization in decellularized liver matrix via activating the IL-6/Stat3 pathway

2016 ◽  
Vol 11 (6) ◽  
pp. 065007 ◽  
Author(s):  
Xudong Wen ◽  
Hongbo Huan ◽  
Xiaojun Wang ◽  
Xuejiao Chen ◽  
Lili Wu ◽  
...  
Keyword(s):  
Stat3 Pathway ◽  
Decellularized Liver
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