Lysine Methyltransferases and Their Inhibitors

2019 ◽  
pp. 123-157
Author(s):  
Giulia Stazi ◽  
Clemens Zwergel ◽  
Sergio Valente
Keyword(s):  
Lysine Methyltransferases

scholarly journals Methylation of geometrically constrained lysine analogues by histone lysine methyltransferases

2020 ◽  
Vol 56 (20) ◽  
pp. 3039-3042 ◽  
Author(s):  
Abbas H. K. Al Temimi ◽  
Paul B. White ◽  
Marcus J. M. Mulders ◽  
Nicole G. A. van der Linden ◽  
Richard H. Blaauw ◽  
...  
Keyword(s):  
Substrate Specificity ◽  
Histone Lysine ◽  
Lysine Methyltransferases ◽  
Geometrically Constrained ◽  
Histone Lysine Methyltransferases

Histone lysine methyltransferases (KMTs) exhibit substrate specificity for lysine and its geometrically constrained mimics.

scholarly journals MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Sugiko Watanabe ◽  
Makoto Iimori ◽  
David Virya Chan ◽  
Eiji Hara ◽  
Hiroyuki Kitao ◽  
...  
Keyword(s):  
Dna Damage ◽  
Lysine Methyltransferases

Role of Histone Lysine Methyltransferases SUV39H1 and SETDB1 in Gliomagenesis: Modulation of Cell Proliferation, Migration, and Colony Formation

2013 ◽  
Vol 16 (1) ◽  
pp. 70-82 ◽  
Author(s):  
Anastasia Spyropoulou ◽  
Antonios Gargalionis ◽  
Georgia Dalagiorgou ◽  
Christos Adamopoulos ◽  
Kostas A. Papavassiliou ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Colony Formation ◽  
Histone Lysine ◽  
Lysine Methyltransferases ◽  
Histone Lysine Methyltransferases

scholarly journals Lysine methyltransferase inhibitors: where we are now.

2022 ◽  
Author(s):  
Alessandra Feoli ◽  
Monica Viviano ◽  
Alessandra Cipriano ◽  
Ciro Milite ◽  
Sabrina Castellano ◽  
...  
Keyword(s):  
Large Family ◽  
Methyl Group ◽  
Lysine Methyltransferase ◽  
Lysine Methyltransferases

Protein lysine methyltransferases constitute a large family of epigenetic writers which catalyse the transfer of a methyl group from the cofactor S-adenosyl-L-methionine to histone and non-histone specific substrates. Alterations in...

scholarly journals Role of several histone lysine methyltransferases in tumor development

2016 ◽  
Vol 4 (3) ◽  
pp. 293-299 ◽  
Author(s):  
JIFU LI ◽  
SHUNQIN ZHU ◽  
XIAO-XUE KE ◽  
HONGJUAN CUI
Keyword(s):  
Tumor Development ◽  
Histone Lysine ◽  
Lysine Methyltransferases ◽  
Histone Lysine Methyltransferases

Abstract A39: Nuclear SET domain (NSD) protein lysine methyltransferases (KMT) are higher expressed in acute myeloid leukemia

2018 ◽  
Author(s):  
Virginia Mara de Deus Wagatsuma ◽  
Luisa C. A. Koury ◽  
Silvia Helena Sánchez ◽  
Lorena Lobo Figueiredo-Pontes ◽  
Fernanda Borges da Silva ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Set Domain ◽  
Lysine Methyltransferases ◽  
Acute Myeloid
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