Rational Design of Multifunctional Nanoscale Self-Assembled Soft Materials for Biomedical Delivery Application

2014 ◽  
pp. 55-73 ◽  
Author(s):  
Shrinivas Venkataraman
Keyword(s):  
Rational Design ◽  
Soft Materials ◽  
Self Assembled

ChemInform Abstract: Functional Soft Materials: Nanostructured Liquid Crystals and Self-Assembled Fibrous Aggregates

ChemInform ◽  
2011 ◽  
Vol 42 (16) ◽  
pp. no-no
Author(s):  
Takashi Kato ◽  
Yoshiko Shoji ◽  
Masafumi Yoshio ◽  
Shogo Yamane ◽  
Takuma Yasuda
Keyword(s):  
Liquid Crystals ◽  
Soft Materials ◽  
Self Assembled

A Chiroptical Logic Circuit Based on Self-Assembled Soft Materials Containing Amphiphilic Spiropyran

2015 ◽  
Vol 28 (8) ◽  
pp. 1644-1649 ◽  
Author(s):  
Changxia Liu ◽  
Dong Yang ◽  
Qingxian Jin ◽  
Li Zhang ◽  
Minghua Liu
Keyword(s):  
Soft Materials ◽  
Logic Circuit ◽  
Self Assembled

Rational Design of a Tetrameric Protein to Enhance Interactions between Self-Assembled Fibers Gives Molecular Hydrogels

2012 ◽  
Vol 51 (18) ◽  
pp. 4388-4392 ◽  
Author(s):  
Xiaoli Zhang ◽  
Xinlei Chu ◽  
Ling Wang ◽  
Huaimin Wang ◽  
Gaolin Liang ◽  
...  
Keyword(s):  
Rational Design ◽  
Self Assembled

Primary ion fluence dependence in time-of-flight SIMS of a self-assembled monolayer of octadecylphosphonic acid molecules on mica discussion of static limit

2007 ◽  
Vol 85 (12) ◽  
pp. 1075-1082 ◽  
Author(s):  
M Nieradko ◽  
N W Ghonaim ◽  
L Xi ◽  
H Y Nie ◽  
J Francis ◽  
...  
Keyword(s):  
Secondary Ion Mass Spectrometry ◽  
Time Of Flight ◽  
Static Condition ◽  
Soft Materials ◽  
Self Assembled Monolayer ◽  
Atomic Ions ◽  
Tof Sims ◽  
Self Assembled ◽  
Octadecylphosphonic Acid ◽  
Fluence Range

By using a self-assembled monolayer of octadecylphosphonic acid molecules, CH3(CH2)17PO(OH)2, on mica as a model of the “soft” materials, such as self-assembled monolayers (SAMs) and multilayers in many biological systems as well as artificially engineered molecular electronic systems, we have examined the effects of primary ion fluence on time-of-flight secondary ion mass spectrometry (TOF-SIMS) of the technologically important model. Our measurements clearly show that although the intensity per unit primary ion fluence of most atomic ions and many small fragment ions do not vary by more than 10% for the fluence range of 1010–1013 cm–2, the intensity of the parent molecular ion can drop by two orders of magnitude in this fluence range. While the changes are different for the primary ion beams of Bi3+ (25 keV, 45°), Bi+ (25 keV, 45°), and Ar+ (8 keV, 45°), they are all substantial, with the damage cross section induced by the Bi3+ beam being the largest (6 000 Å2). Since different secondary ions have quite different intensity changes, the analytical results derived from TOF-SIMS can vary significantly by the time and duration of the measurements in the TOF-SIMS experiment. Therefore, our results suggest that for TOF-SIMS of molecular layers such as SAMs, the primary ion fluence condition should be recorded and reported. In general, the validity of the static condition becomes questionable when the cumulative primary ion fluence exceeds 1 × 1011 cm–2.Key words: SIMS, static SIMS, TOF-SIMS, soft materials, self-assembled monolayer, bilayer, surface of biological materials.

scholarly journals Phospholes: Molecular Engineering of “Click”-Phospholes Towards Self-Assembled Luminescent Soft Materials (Adv. Funct. Mater. 7/2014)

2014 ◽  
Vol 24 (7) ◽  
pp. 877-877 ◽  
Author(s):  
Xiaoming He ◽  
Jian-Bin Lin ◽  
Wang Hay Kan ◽  
Pengcheng Dong ◽  
Simon Trudel ◽  
...  
Keyword(s):  
Soft Materials ◽  
Molecular Engineering ◽  
Self Assembled

scholarly journals Multi-component, Self-assembled, Functional Soft Materials

2013 ◽  
Vol 67 (1) ◽  
pp. 44-50 ◽  
Author(s):  
V. S. Sajisha ◽  
Uday Maitra
Keyword(s):  
Soft Materials ◽  
Self Assembled

scholarly journals Reorganization of Self-Assembled DNA-Based Polymers Using Orthogonally Addressable Building Blocks

2021 ◽  
Author(s):  
Serena Gentile ◽  
Erica Del Grosso ◽  
Leonard J. Prins ◽  
Francesco Ricci
Keyword(s):  
Self Assembly ◽  
Rational Design ◽  
Building Blocks ◽  
Binding Domain ◽  
Non Covalent Interactions ◽  
Sticky Ends ◽  
Self Assembled ◽  
Block Structures ◽  
Covalent Interactions

Taking advantage of the addressability and programmability of DNA/DNA non-covalent interactions we report here the rational design of orthogonal DNA-based addressable tiles that self-assemble into polymer-like structures that can be reconfigured and reorganized by external inputs. The different tiles share the same 5-nucleotide sticky ends responsible for self-assembly but are rationally designed to contain a specific regulator-binding domain that can be orthogonally targeted by different DNA regulator strands (activators and inhibitors). We show that by sequentially adding specific activators and inhibitors it is possible to re-organize in a dynamic and reversible way the formed polymer-like structures to display well-defined distributions: homopolymers made of a single tile, random polymers in which different tiles are distributed randomly and block structures in which the tiles are organized in segments.

scholarly journals Geometry induced sequence of nanoscale Frank–Kasper and quasicrystal mesophases in giant surfactants

2016 ◽  
Vol 113 (50) ◽  
pp. 14195-14200 ◽  
Author(s):  
Kan Yue ◽  
Mingjun Huang ◽  
Ryan L. Marson ◽  
Jinlin He ◽  
Jiahao Huang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Brownian Dynamics ◽  
Molecular Model ◽  
Critical Role ◽  
Sphere Packing ◽  
Molecular Geometry ◽  
Soft Materials ◽  
Real Space ◽  
Molecular Architecture ◽  
Self Assembled

Frank–Kasper (F-K) and quasicrystal phases were originally identified in metal alloys and only sporadically reported in soft materials. These unconventional sphere-packing schemes open up possibilities to design materials with different properties. The challenge in soft materials is how to correlate complex phases built from spheres with the tunable parameters of chemical composition and molecular architecture. Here, we report a complete sequence of various highly ordered mesophases by the self-assembly of specifically designed and synthesized giant surfactants, which are conjugates of hydrophilic polyhedral oligomeric silsesquioxane cages tethered with hydrophobic polystyrene tails. We show that the occurrence of these mesophases results from nanophase separation between the heads and tails and thus is critically dependent on molecular geometry. Variations in molecular geometry achieved by changing the number of tails from one to four not only shift compositional phase boundaries but also stabilize F-K and quasicrystal phases in regions where simple phases of spheroidal micelles are typically observed. These complex self-assembled nanostructures have been identified by combining X-ray scattering techniques and real-space electron microscopy images. Brownian dynamics simulations based on a simplified molecular model confirm the architecture-induced sequence of phases. Our results demonstrate the critical role of molecular architecture in dictating the formation of supramolecular crystals with “soft” spheroidal motifs and provide guidelines to the design of unconventional self-assembled nanostructures.

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