scholarly journals Polyphosphoinositide-Binding Domains: Insights from Peripheral Membrane and Lipid-Transfer Proteins

2018 ◽  
pp. 77-137 ◽  
Author(s):  
Joshua G. Pemberton ◽  
Tamas Balla
Keyword(s):  
Lipid Transfer ◽  
Lipid Transfer Proteins ◽  
Binding Domains

The role of the phosphoinositides at the Golgi complex

2007 ◽  
Vol 74 ◽  
pp. 107-116 ◽  
Author(s):  
Maria Antonietta De Matteis ◽  
Giovanni D'Angelo
Keyword(s):  
Golgi Complex ◽  
Small Gtpases ◽  
Eukaryotic Cells ◽  
Lipid Transfer ◽  
Lipid Transfer Proteins ◽  
Cell Organelles ◽  
Binding Domains ◽  
Ability To Act ◽  
Endocytic Pathways

Eukaryotic cells are organized into a complex system of subcompartments, each with its distinct protein and lipid composition. A continuous flux of membranes crosses these compartments, and in some cases direct connections exist between the different organelles. It is thus surprising that they can maintain their individual identities. Small GTPases and the phosphoinositides have emerged as the key regulators in the maintenance of the identity of the Golgi complex. This property is due to their ability to act either alone or, more often, in combination, as cues directing and controlling the recruitment of proteins that possess phosphoinositide-binding domains. Among these many proteins there are the lipid transfer proteins, which can transfer ceramide, oxysterol, cholesterol and possibly glucosylceramide. By regulating these lipid transfer proteins in this way, this binomial combination of the small GTPases and the phosphoinositides acquires a further important role: control of the synthesis and/or distribution of other important integral constituents of cell organelles, such as the sphingolipids and cholesterol. This role is particularly relevant at the level of the Golgi complex, a key organelle in the biosynthesis, transport and sorting of both lipids and proteins that is located at the intersection of the secretory and endocytic pathways.

scholarly journals Non‐specific lipid‐transfer proteins: Allergen structure and function, cross‐reactivity, sensitization, and epidemiology

2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Isabel J. Skypala ◽  
Ricardo Asero ◽  
Domingo Barber ◽  
Lorenzo Cecchi ◽  
Arazeli Diaz Perales ◽  
...  
Keyword(s):  
Cross Reactivity ◽  
Structure And Function ◽  
Lipid Transfer ◽  
Lipid Transfer Proteins ◽  
Allergen Structure ◽  
And Function ◽  
Specific Lipid

scholarly journals Advances on the Transfer of Lipids by Lipid Transfer Proteins

2017 ◽  
Vol 42 (7) ◽  
pp. 516-530 ◽  
Author(s):  
Louise H. Wong ◽  
Alenka Čopič ◽  
Tim P. Levine
Keyword(s):  
Lipid Transfer ◽  
Lipid Transfer Proteins

Role of plant lipid transfer proteins in plant cell physiology—A concise review

Peptides ◽  
2007 ◽  
Vol 28 (5) ◽  
pp. 1144-1153 ◽  
Author(s):  
André de Oliveira Carvalho ◽  
Valdirene Moreira Gomes
Keyword(s):  
Plant Cell ◽  
Cell Physiology ◽  
Lipid Transfer ◽  
Lipid Transfer Proteins ◽  
Plant Lipid ◽  
Concise Review
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