Stem Cell Therapy: Repurposing Cell-Based Regenerative Medicine Beyond Cell Replacement

2018 ◽  
pp. 87-91 ◽  
Author(s):  
Eleonora Napoli ◽  
Trenton Lippert ◽  
Cesar V. Borlongan
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Cell Replacement

scholarly journals Stem Cell Therapy and Regenerative Medicine

2009 ◽  
Vol 84 (10) ◽  
pp. 859-861 ◽  
Author(s):  
Timothy O'Brien ◽  
Frank P. Barry
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Cell Therapy ◽  
Stem Cell Therapy

scholarly journals Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Michelle R. Santoso ◽  
Phillip C. Yang
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Iron Oxide ◽  
Regenerative Medicine ◽  
Cell Therapy ◽  
Iron Oxide Nanoparticles ◽  
Stem Cell Therapy ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Stem cell therapy has broad applications in regenerative medicine and increasingly within cardiovascular disease. Stem cells have emerged as a leading therapeutic option for many diseases and have broad applications in regenerative medicine. Injuries to the heart are often permanent due to the limited proliferation and self-healing capability of cardiomyocytes; as such, stem cell therapy has become increasingly important in the treatment of cardiovascular diseases. Despite extensive efforts to optimize cardiac stem cell therapy, challenges remain in the delivery and monitoring of cells injected into the myocardium. Other fields have successively used nanoscience and nanotechnology for a multitude of biomedical applications, including drug delivery, targeted imaging, hyperthermia, and tissue repair. In particular, superparamagnetic iron oxide nanoparticles (SPIONs) have been widely employed for molecular and cellular imaging. In this mini-review, we focus on the application of superparamagnetic iron oxide nanoparticles in targeting and monitoring of stem cells for the treatment of myocardial infarctions.

Anti-HLA antibodies in regenerative medicine stem cell therapy

2012 ◽  
Vol 73 (12) ◽  
pp. 1287-1294 ◽  
Author(s):  
Dominique Charron ◽  
Caroline Suberbielle-Boissel ◽  
Ryad Tamouza ◽  
Reem Al-Daccak
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Hla Antibodies

Recent Research and Development in Stem Cell Therapy for Cancer Treatment

2021 ◽  
pp. 514-533
Author(s):  
Nagendra Kumar Chandrawanshi ◽  
Shekhar Verma
Keyword(s):  
Stem Cell ◽  
Regenerative Medicine ◽  
Cell Therapy ◽  
Cancer Treatment ◽  
Stem Cell Therapy ◽  
Cancer Genomics ◽  
Target Therapy ◽  
Rapid Development ◽  
Organ Specific ◽  
The Individual

Cancer is the most prevalent and dangerous disease, and it leads to millions of deaths worldwide. Generally, metastatic cancer cells are not eradication by conventional surgical operative or chemotherapy-based treatment. New pathways have been established in various arenas such as unique biology, modulators regulatory mechanism, directional migration, self-renewal, etc. The individual pathways can be employed as therapeutic carriers, specific drug targeting, generation of acquiring nature immune cells, and regenerative medicine. The present scenario, stem cell therapy, focused on a promising tool for targeted cancer treatment. Stem cells also utilized as viruses and nanoparticles carry to enhance the primary therapeutic application in various dimensions such as cancer target therapy, regenerative medicine, immune-modulating therapy, and anticancer drugs screening. Furthermore, the rapid development in next-generation sequencing techniques and cancer genomics and proteomics analysis approaches are making therapeutics targeting organ-specific cancer more precise and efficient.

Stem cell therapy for cardiac regeneration: hits and misses

2015 ◽  
Vol 93 (10) ◽  
pp. 835-841 ◽  
Author(s):  
Jagjit Padda ◽  
Glen Lester Sequiera ◽  
Niketa Sareen ◽  
Sanjiv Dhingra
Keyword(s):  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Cardiac Injury ◽  
Cardiac Regeneration ◽  
Cardiovascular Disorders ◽  
Adult Tissue ◽  
Cell Replacement ◽  
Clinical Scenarios ◽  
The World

Cardiac injury and loss of cardiomyocytes is a causative as well as a resultant condition of cardiovascular disorders, which are the leading cause of death throughout the world. This loss of cardiomyocytes cannot be completely addressed through the currently available drugs being administered, which mainly function only in relieving the symptoms. There is a huge potential being investigated for regenerative and cell replacement therapies through recruiting stem cells of various origins namely embryonic, reprogramming/induction, and adult tissue. These sources are being actively studied for translation to clinical scenarios. In this review, we attempt to discuss some of these promising scenarios, including the clinical trials and the obstacles that need to be overcome, and hope to address the direction in which stem cell therapy is heading.

Sign in / Sign up

Export Citation Format

Share Document