Electronic Cigarettes and Awareness of Their Health Effects

2017 ◽  
pp. 1-8 ◽  
Author(s):  
A. Daniluk ◽  
A. Gawlikowska-Sroka ◽  
M. Stępien-Słodkowska ◽  
E. Dzięciołowska-Baran ◽  
K. Michnik
Keyword(s):  
Health Effects ◽  
Electronic Cigarettes

scholarly journals Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums (Preprint)

2019 ◽  
Author(s):  
My Hua ◽  
Shouq Sadah ◽  
Vagelis Hristidis ◽  
Prue Talbot
Keyword(s):  
Health Effects ◽  
Electronic Cigarettes ◽  
Health Effect ◽  
Online Information ◽  
Online Forums ◽  
Unified Medical Language System ◽  
Organ Systems ◽  
Negative Sentiment ◽  
Specific Symptoms ◽  
Medical Concepts

BACKGROUND Our previous infodemiological study was performed by manually mining health-effect data associated with electronic cigarettes (ECs) from online forums. Manual mining is time consuming and limits the number of posts that can be retrieved. OBJECTIVE Our goal in this study was to automatically extract and analyze a large number (>41,000) of online forum posts related to the health effects associated with EC use between 2008 and 2015. METHODS Data were annotated with medical concepts from the Unified Medical Language System using a modified version of the MetaMap tool. Of over 1.4 million posts, 41,216 were used to analyze symptoms (undiagnosed conditions) and disorders (physician-diagnosed terminology) associated with EC use. For each post, sentiment (positive, negative, and neutral) was also assigned. RESULTS Symptom and disorder data were categorized into 12 organ systems or anatomical regions. Most posts on symptoms and disorders contained negative sentiment, and affected systems were similar across all years. Health effects were reported most often in the neurological, mouth and throat, and respiratory systems. The most frequently reported symptoms and disorders were headache (n=939), coughing (n=852), malaise (n=468), asthma (n=916), dehydration (n=803), and pharyngitis (n=565). In addition, users often reported linked symptoms (eg, coughing and headache). CONCLUSIONS Online forums are a valuable repository of data that can be used to identify positive and negative health effects associated with EC use. By automating extraction of online information, we obtained more data than in our prior study, identified new symptoms and disorders associated with EC use, determined which systems are most frequently adversely affected, identified specific symptoms and disorders most commonly reported, and tracked health effects over 7 years.

scholarly journals A cigaretta, az elektromos cigaretta és a vízipipa egészségre gyakorolt hatása

2021 ◽  
Vol 162 (3) ◽  
pp. 83-90
Author(s):  
Árpád Farkas ◽  
Gábor Tomisa ◽  
Erika Kis ◽  
Alpár Horváth
Keyword(s):  
Health Effects ◽  
Scientific Literature ◽  
Electronic Cigarettes ◽  
Neurological Diseases ◽  
Convincing Evidence ◽  
Acute Effects ◽  
Negative Effects ◽  
Policy Makers ◽  
Pertinent Information

Összefoglaló. A dohányzás káros hatásainak vizsgálata hosszú ideje az orvostudomány egyik legintenzívebben kutatott területe. A nagy tudományos érdeklődésnek köszönhetően ma már meggyőző evidenciák állnak rendelkezésre a hagyományos cigaretta használatának számos negatív hatásáról. Ezzel ellentétben a sokkal később bevezetett helyettesítő termékek veszélyeiről lényegesen kevesebbet tudunk. E körbe tartozik a manapság egyre népszerűbb elektromos cigaretta is, amelyre egyre több, egészségügyi kockázatot felmérő munka fókuszál. Ugyanakkor a több évszázados múltra visszatekintő és a világ bizonyos helyein sokáig népszerű vízipipa érdekes esetnek számít, mivel használóinak száma a nyugati világban az utóbbi időben megugrott, de az emberre gyakorolt hatása számos ponton még vita tárgyát képezi. A jelen munka célja, hogy a hazai és a nemzetközi szakirodalom alapján feltérképezze a hagyományos cigaretta, az elektromos cigaretta és a vízipipa fontosabb egészségügyi hatásait, és rámutasson azokra a kapcsolódó területekre, ahol további kutatások szükségesek. A szakirodalmi áttekintés során a különböző publikációs adatbázisokban fellelhető tudományos cikkeket elemeztük. A megvizsgált szakirodalom alapján a tartós dohányzásnak bizonyítottan a szív-ér rendszert és a légzőrendszert károsító hatása van, de növekvő számú bizonyíték utal a neurológiai káros hatásokra és a gasztroenterológiai hatásokra is. Ugyanakkor az elektromos cigaretta és a vízipipa esetében a bizonyított akut hatások mellett a hosszú távú hatásokat illetően további intenzív kutatásokra van szükség. Az elektromos cigaretta és a vízipipa esetében a hosszú távú hatások kapcsán a meggyőző evidencia hiánya semmiképpen nem jelenti azt, hogy ezen termékeket kockázatmentesnek kellene tekinteni, sőt a pulmonológusoknak és a döntéshozóknak mindent meg kell tenniük annak érdekében, hogy valamennyi dohánytermék törvényi szabályozása azok használatának visszaszorítását célozza. A kérdés fontosságának a COVID–19-pandémia különös aktualitást ad. Orv Hetil. 2021; 162(3): 83–90. Summary. Revealing the health effects associated with smoking has been in the focus of intense research for decades. Due to these research efforts, there is a convincing evidence regarding the negative effects of conventional cigarettes. However, much less is known about the replacement products such as electronic cigarettes. Moreover, the effects of waterpipes are also not fully explored, in spite of their long history. The scope of the present work is to survey the open literature to map the knowledge related to the health effects of conventional cigarettes, e-cigarettes and waterpipes. The analysis of the related scientific literature was performed based on papers retrieved in large publication repositories. Based on the reviewed literature, long-term smoking has demonstrated adverse effects on the respiratory as well as the heart and circulatory systems. In addition, the correlation between cigarette smoking and some gastroenterological and neurological diseases is also increasingly evident. By the same token, though the acute effects of e-cigarette and waterpipe are well documented, the protracted effects are still to be explored. The lack of pertinent information regarding the late effects of e-cigarette and hookah does not imply that there is no health risk associated with their consumption. On the contrary, in addition to the regular antismoke measures, pulmonologists and policy makers should do everything to lower the consumption of these alternative products. Orv Hetil. 2021; 162(3): 83–90.

scholarly journals Exosomal microRNAs are novel circulating biomarkers in cigarette, waterpipe smokers, E-cigarette users and dual smokers

2020 ◽  
Author(s):  
Kameshwar P. Singh ◽  
Krishna P. Maremanda ◽  
Dongmei Li ◽  
Irfan Rahman
Keyword(s):  
Differential Expression ◽  
Health Effects ◽  
Molecular Mechanisms ◽  
Electronic Cigarettes ◽  
Differential Expression Analysis ◽  
Pairwise Comparison ◽  
Gene Set Enrichment Analysis ◽  
Cigarette Smoke Exposure ◽  
Tobacco Exposure ◽  
Non Coding Rnas

Abstract Background Electronic cigarettes (e-cigs) produce aerosolized substances by heating a liquid, which contains large number of chemicals. The aerosol generated by E-cig may produce serious health effects. Cigarette smoke exposure may causes various diseases including COPD, atherosclerosis, and lung cancer. Waterpipe tobacco smoking also causes various acute and chronic health effects including cardiopulmonary diseases. MicroRNAs are present in higher concentration in exosomes that play a major role in various normal physiological functions and diseases. We hypothesized that the non-coding RNAs transcript may serve as susceptibility to disease biomarkers by smoking and vaping. Results Our data show the enrichment of various non-coding RNAs that include microRNAs, tRNAs, piRNAs, snoRNAs, snRNAs, Mt-tRNAs, and other biotypes in exosomes. The detailed differential expression analysis of microRNAs, tRNAs and piRNA showed significant changes between pairwise comparisons of different groups. The common changes in differential expression of 8 microRNAs that are hsa-let-7a-5p, hsa-miR-21-5p, hsa-miR-29b-3p, hsa-let-7f-5p, hsa-miR-143-3p, hsa-miR-30a-5p, hsa-let-7i-5p, and hsa-let-7g-5p were found when compared with all smoking and vaping groups with non-smoking group. The e-cig group has differentially expressed 7 microRNAs (hsa-miR-224-5p, hsa-let-7c-5p, hsa-miR-193b-3p, hsa-miR-30e-5p, hsa-miR-423-3p, hsa-miR-500b-3p, hsa-miR-365a-3p|hsa-miR-365b-3p) that is specific for this group, not expressed in other three groups. Gene set enrichment analysis of microRNA showed significant changes in the top six enriched functions that consisted of biological pathway, biological process, molecular function, cellular component, site of expression and transcription factor in all groups. Further, the pairwise comparison of tRNAs and piRNA in all groups also revealed significant changes in differential expression. Conclusions Plasma exosomes of cigarette smokers, waterpipe smokers, e-cig users and dual smokers have common differential expression of microRNAs (hsa-let-7a-5p, hsa-miR-21-5p, hsa-miR-29b-3p, hsa-let-7f-5p, hsa-miR-143-3p, hsa-miR-30a-5p, hsa-let-7i-5p, and hsa-let-7g-5p), may be biomarker for tobacco exposure. Additionally, the e-cig users have also differential expressed microRNAs (hsa-miR-224-5p, hsa-let-7c-5p, hsa-miR-193b-3p, hsa-miR-30e-5p, hsa-miR-423-3p, hsa-miR-500b-3p, and hsa-miR-365a-3p|hsa-miR-365b-3p) that is specific for this group. This study will help to better understand molecular mechanisms of plasma exosome non-coding RNAs and in developing biomarkers that may be useful in diagnosis and therapy of pulmonary injury and disease by smoking and vaping.

scholarly journals Are E-Cigarette Flavors Associated with Exposure to Nicotine and Toxicants? Findings from Wave 2 of the Population Assessment of Tobacco and Health (PATH) Study

2019 ◽  
Vol 16 (24) ◽  
pp. 5055 ◽  
Author(s):  
Danielle M. Smith ◽  
Liane M. Schneller ◽  
Richard J. O’Connor ◽  
Maciej L. Goniewicz
Keyword(s):  
Health Effects ◽  
Electronic Cigarettes ◽  
Population Assessment

Increasing adoption of electronic cigarettes (e-cigarettes) has led to numerous concerns about health effects resulting from long-term use [...]

scholarly journals Health effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up

2018 ◽  
Vol Volume 13 ◽  
pp. 2533-2542 ◽  
Author(s):  
Riccardo Polosa ◽  
Jaymin Morjaria ◽  
Umberto Prosperini ◽  
Cristina Russo ◽  
Alfio Pennisi ◽  
...  
Keyword(s):  
Health Effects ◽  
Electronic Cigarettes

scholarly journals Electronic Cigarette Toxicity

2016 ◽  
Vol 8 (2) ◽  
pp. 100-102 ◽  
Author(s):  
J. Drew Payne ◽  
David Michaels ◽  
Menfil Orellana-Barrios ◽  
Kenneth Nugent
Keyword(s):  
Health Effects ◽  
Drug Administration ◽  
Electronic Cigarettes ◽  
Case Reports ◽  
Poison Control ◽  
Federal Regulation ◽  
Limited Data ◽  
Adverse Health Effects ◽  
The Past ◽  
The Us

Electronic cigarettes (e-cigarettes) are often advertised as a healthier product when compared with traditional cigarettes. Currently, there are limited data to support this and only a threat of federal regulation from the US Food and Drug Administration. Calls to poison control centers about e-cigarette toxicity, especially in children, and case reports of toxic exposures have increased over the past 3 years. This research letter reports the frequency of hazardous exposures to e-cigarettes and characterizes the reported adverse health effects associated with e-cigarette toxicity.

scholarly journals Pulmonary Health Effects of Electronic Cigarettes: A Scoping Review

2021 ◽  
pp. 152483992098550
Author(s):  
Emma Gugala ◽  
Chinyere M. Okoh ◽  
Somraj Ghosh ◽  
Leticia R. Moczygemba
Keyword(s):  
Public Health ◽  
Health Effects ◽  
Scoping Review ◽  
Electronic Cigarettes ◽  
The United States ◽  
Disease Diagnosis ◽  
Adverse Outcomes ◽  
Chronic Obstructive ◽  
Original Research ◽  
Dual Use

Background There is global concern regarding the public health impact of electronic cigarettes (ECs). ECs are commonly promoted as safer than conventional cigarettes (CCs), however there is limited knowledge of the long-term health effects. This scoping review examined the pulmonary health effects of ECs reported in the literature from 2009 to 2019. Method PubMed, CINAHL, and Science Direct databases were used. Search terms included “vaping, electronic nicotine delivery systems, electronic cigarettes, lung diseases, respiratory diseases, and pulmonary.” Original research articles in English that used human subjects between January 1, 2009 and January 31, 2020 and reported pulmonary outcomes were included. Results Forty-five studies met the inclusion criteria. There were 14 (31.1%) randomized experimental, 7 (15.6%) nonrandomized experimental, 6 (13.3%) cohort, and 18 (40.0%) cross-sectional studies. Sixteen (35.6%) studies were conducted in the United States; the rest were conducted across 11 other countries. The total number of subjects was 1,465,292 and ages ranged from 12 to 99 years across studies. Eligible studies demonstrated an association between EC use and pulmonary symptoms, asthma and chronic obstructive pulmonary disease diagnosis and exacerbations. The degree of this association varied based on the use of additional tobacco products. EC use resulted in worse outcomes than nonsmoking, but resulted in improved outcomes when compared with CC use or dual use of CC and EC. Conclusion Evidence indicates that EC use, especially dual use, leads to negative pulmonary effects and adverse outcomes. Education on the potential risks and publishing of EC ingredients on labels could help improve public health safety communication and reduce EC use.

scholarly journals Electronic Cigarettes and Oral Health

2021 ◽  
pp. 002203452110021
Author(s):  
R. Holliday ◽  
B.W. Chaffee ◽  
N.S. Jakubovics ◽  
R. Kist ◽  
P.M. Preshaw
Keyword(s):  
Oral Health ◽  
Health Effects ◽  
Tobacco Smoking ◽  
Electronic Cigarettes ◽  
Mode Of Delivery ◽  
In Vitro Studies ◽  
Future Research ◽  
Health Consequences ◽  
The Past

Novel nicotine products, particularly electronic cigarettes (e-cigarettes), have become increasingly popular over the past decade. E-cigarettes are sometimes regarded as a less harmful alternative to tobacco smoking, and there is some evidence of their potential role as a smoking cessation aid. However, there are concerns about their health consequences, particularly in users who are not tobacco smokers, and also when used long term. Given the mode of delivery of these products, there is potential for oral health consequences. Over the past few years, there have been an increasing number of studies conducted to explore their oral health effects. In vitro studies have reported a range of cellular effects, but these are much less pronounced than those resulting from exposure to tobacco smoke. Microbiological studies have indicated that e-cigarette users have a distinct microbiome, and there is some indication this may be more pathogenic compared to nonusers. Evidence of oral health effects from clinical trials is still limited, and most studies to date have been small in scale and usually cross-sectional in design. Epidemiological studies highlight concerns over oral dryness, irritation, and gingival diseases. Interpreting data from e-cigarette studies is challenging, given the different populations that have been investigated and the continual emergence of new products. Overall, studies reveal potential oral health harms, underscoring the importance of efforts to reduce use in nonsmokers. However, in smokers who are using e-cigarettes as an aid to help them quit, the benefits of quitting tobacco smoking may outweigh any negative oral health impacts of e-cigarette use, particularly in the short term. Future research is needed to understand the clinical significance of some of the biological changes observed by following different cohorts of users longitudinally in carefully designed clinical studies and pragmatic trials supported by high-quality in vitro studies.

Sign in / Sign up

Export Citation Format

Share Document