Age and Gender-Related Changes in Biogenic Amine Metabolites in Cerebrospinal Fluid in Children

2015 ◽  
pp. 73-82 ◽  
Author(s):  
Katarzyna Kuśmierska ◽  
Krystyna Szymańska ◽  
Dariusz Rokicki ◽  
Katarzyna Kotulska ◽  
Sergiusz Jóźwiak ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Biogenic Amine ◽  
Age And Gender ◽  
And Gender

Abnormal galactosylation of immunoglobulin G in cerebrospinal fluid of multiple sclerosis patients

2016 ◽  
Vol 22 (14) ◽  
pp. 1794-1803 ◽  
Author(s):  
Yann Decker ◽  
Robert Schomburg ◽  
Eszter Németh ◽  
Artem Vitkin ◽  
Mathias Fousse ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Immunoglobulin G ◽  
Viral Meningitis ◽  
Brain Inflammation ◽  
Age And Gender ◽  
History Of ◽  
And Gender ◽  
Multiple Sclerosis Patients ◽  
And Control

Background: Glycosylation alterations have been associated with the development of several human diseases and their animal models, including multiple sclerosis. Objectives: We aimed to determine whether immunoglobulin G galactosylation might be changed in multiple sclerosis. Methods: Immunoglobulin G was isolated from serum and cerebrospinal fluid of patients with multiple sclerosis or viral meningitis and control patients without history of inflammatory or autoimmune disease. A lectin-based assay was used to investigate potential galactosylation modifications of immunoglobulin G. Results and conclusion: Galactosylation of immunoglobulin G isolated from cerebrospinal fluid of control patients was found to be age- and gender-dependent. In addition, immunoglobulin G galactosylation was significantly altered in cerebrospinal fluid but not in serum of multiple sclerosis patients. Furthermore, this modification was correlated with an active progression of multiple sclerosis. Finally, the loss of galactosyl moieties was not simply associated with inflammation as no such change was detected in viral meningitis patients characterized by brain inflammation.

Empirical Analysis of Clinical Evaluations on Children Involved in the Child Protection System: The Role of Age and Gender

2000 ◽  
Author(s):  
Erika Felix ◽  
Anjali T. Naik-Polan ◽  
Christine Sloss ◽  
Lashaunda Poindexter ◽  
Karen S. Budd
Keyword(s):  
Empirical Analysis ◽  
Child Protection ◽  
Protection System ◽  
Age And Gender ◽  
Clinical Evaluations ◽  
And Gender

Effect of antihistamine, age, and gender on task performance

1999 ◽  
Author(s):  
Kirby Gilliland ◽  
Robert E. Schlegel ◽  
Thomas E. Nesthus
Keyword(s):  
Task Performance ◽  
Age And Gender ◽  
And Gender
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