Endostatin and Cathepsin-V in Bronchoalveolar Lavage Fluid of Patients with Pulmonary Sarcoidosis

2014 ◽  
pp. 55-61 ◽  
Author(s):  
W. Naumnik ◽  
M. Ossolińska ◽  
I. Płońska ◽  
E. Chyczewska ◽  
J. Nikliński
Keyword(s):  
Bronchoalveolar Lavage ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Sarcoidosis ◽  
Cathepsin V

scholarly journals Imaging Changes and Immune-Checkpoint Expression on T Cells in Bronchoalveolar Lavage Fluid from Patients with Pulmonary Sarcoidosis

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1231
Author(s):  
Yasuaki Kotetsu ◽  
Toyoshi Yanagihara ◽  
Kunihiro Suzuki ◽  
Hiroyuki Ando ◽  
Daisuke Eto ◽  
...  
Keyword(s):  
T Cells ◽  
Bronchoalveolar Lavage ◽  
Immune Checkpoint ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Sarcoidosis ◽  
Immune Checkpoint Molecules ◽  
Ct Findings ◽  
Programmed Cell Death 1 ◽  
Spontaneous Improvement

Sarcoidosis is a systemic, granulomatous disease caused by unknown immunological abnormalities. The organs most vulnerable to sarcoidosis are the lungs. Patients often resolve spontaneously, but the lungs can also be severely affected. Although details regarding prognostic factors in sarcoidosis patients with lung involvement remain unclear, several reports have suggested that immune checkpoint molecules are involved in the pathogenesis of sarcoidosis. In this study, we divided sarcoidosis patients into two groups based on chest computed tomography (CT) findings and compared immune checkpoint molecules expressed on T cells in bronchoalveolar lavage fluid (BALF) in the two groups, using flow cytometry. We found elevated programmed cell death 1 (PD-1) or T cell immunoglobulin- and mucin-domain-containing molecule-3 (TIM-3) expression on T cells in BALF in patients with spontaneous improvement in CT findings, compared with those in patients without improvement in CT findings. In conclusion, our study implies that PD-1 or TIM-3 expression on T cells in BALF may be a prognostic factor for pulmonary lesions in sarcoidosis.

Interleukin Levels in the Bronchoalveolar Lavage Fluid of Patients with Pulmonary Sarcoidosis

1998 ◽  
Vol 45 (5) ◽  
pp. 1047
Author(s):  
Jeong Sup Song ◽  
Joong Hyun Ahn ◽  
Chi Hong Kim ◽  
Kwan Hyoung Kim ◽  
Hwa Sik Moon ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Sarcoidosis

Upregulation of Th1 Cytokine Profile (IL-12, IL-18) in Bronchoalveolar Lavage Fluid in Patients with Pulmonary Sarcoidosis

2006 ◽  
Vol 26 (6) ◽  
pp. 400-405 ◽  
Author(s):  
Katerina M. Antoniou ◽  
Argyris Tzouvelekis ◽  
Michael G. Alexandrakis ◽  
Ioanna Tsiligianni ◽  
Nikolaos Tzanakis ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Sarcoidosis ◽  
Cytokine Profile ◽  
Th1 Cytokine

Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis

Respirology ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 1166-1172 ◽  
Author(s):  
Amit Kishore ◽  
Zdenka Navratilova ◽  
Vitezslav Kolek ◽  
Eva Novosadova ◽  
Klára Čépe ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Expression Analysis ◽  
Bronchoalveolar Lavage Fluid ◽  
Lavage Fluid ◽  
Pulmonary Sarcoidosis
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