The Influence of the Reference Values on the Interpretation of Lung Function in Children: Comparison of Global Lung Initiative 2012 and Polish 1998 Reference Values

2014 ◽  
pp. 31-38 ◽  
Author(s):  
Joanna Peradzyńska ◽  
Katarzyna Krenke ◽  
Anna Szylling ◽  
Rafał Krenke ◽  
Marek Kulus
Keyword(s):  
Lung Function ◽  
Reference Values

Lung Function Reference Values in Chinese Children and Adolescents in Hong Kong

2000 ◽  
Vol 162 (2) ◽  
pp. 424-429 ◽  
Author(s):  
MARY S. M. IP ◽  
EVA M. KARLBERG ◽  
JOHAN P. E. KARLBERG ◽  
KEITH D. K. LUK ◽  
JOHN C. Y. LEONG
Keyword(s):  
Hong Kong ◽  
Lung Function ◽  
Children And Adolescents ◽  
Reference Values ◽  
Chinese Children ◽  
Chinese Children And Adolescents

scholarly journals Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian population

2016 ◽  
Vol 48 (6) ◽  
pp. 1602-1611 ◽  
Author(s):  
Arnulf Langhammer ◽  
Ane Johannessen ◽  
Turid L. Holmen ◽  
Hasse Melbye ◽  
Sanja Stanojevic ◽  
...  
Keyword(s):  
Lung Function ◽  
Reference Values ◽  
Vital Capacity ◽  
Population Based ◽  
Forced Expiratory Volume ◽  
Female Adolescents ◽  
Norwegian Population ◽  
Reference Equations ◽  
Z Scores ◽  
Lower Limit Of Normal

We studied the fit of the Global Lung Function Initiative (GLI) all-age reference values to Norwegians, compared them with currently used references (European Community for Steel and Coal (ECSC) and Zapletal) and estimated the prevalence of obstructive lung disease.Spirometry data collected in 30 239 subjects (51.7% females) aged 12–90 years in three population-based studies were converted to z-scores.We studied healthy non-smokers comprising 2438 adults (57.4% females) aged 20–90 years and 8725 (47.7% female) adolescents aged 12–19 years. The GLI-2012 prediction equations fitted the Norwegian data satisfactorily. Median±sd z-scores were respectively 0.02±1.03, 0.01±1.04 and −0.04±0.91 for forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC in males, and −0.01±1.02, 0.07±0.97 and −0.21±0.82 in females. The ECSC and Zapletal references significantly underestimated FEV1 and FVC. Stricter criteria of obstruction (FEV1/FVC <GLI-2012 lower limit of normal (LLN)) carried a substantially higher risk of obstructive characteristics than FEV1/FVC <0.7 and >GLI-2012 LLN. Corresponding comparison regarding myocardial infarction showed a four-fold higher risk for women.The GLI-2012 reference values fit the Norwegian data satisfactorily and are recommended for use in Norway. Correspondingly, the FEV1/FVC GLI-2012 LLN identifies higher risk of obstructive characteristics than FEV1/FVC <0.7.

scholarly journals Lung function reference values in different German populations

2011 ◽  
Vol 105 (3) ◽  
pp. 352-362 ◽  
Author(s):  
Beate Koch ◽  
Christoph Schäper ◽  
Ralf Ewert ◽  
Henry Völzke ◽  
Anne Obst ◽  
...  
Keyword(s):  
Lung Function ◽  
Reference Values

Assessment of Global Lung Function Initiative (GLI) reference equations for diffusing capacity in relation to respiratory burden in the Swedish CArdioPulmonary bioImage Study (SCAPIS)

2020 ◽  
Vol 56 (2) ◽  
pp. 1901995 ◽  
Author(s):  
Andrei Malinovschi ◽  
Xingwu Zhou ◽  
Björn Bake ◽  
Göran Bergström ◽  
Anders Blomberg ◽  
...  
Keyword(s):  
Lung Function ◽  
Reference Values ◽  
Airflow Limitation ◽  
Diffusing Capacity ◽  
High Resolution Computed Tomography ◽  
Swedish Population ◽  
Reference Equations ◽  
Lms Method ◽  
Never Smokers ◽  
Lower Limit Of Normal

The Global Lung Function Initiative (GLI) has recently published international reference values for diffusing capacity of the lung for carbon monoxide (DLCO). Lower limit of normal (LLN), i.e. the 5th percentile, usually defines impaired DLCO. We examined if the GLI LLN for DLCO differs from the LLN in a Swedish population of healthy, never-smoking individuals and how any such differences affect identification of subjects with respiratory burden.Spirometry, DLCO, chest high-resolution computed tomography (HRCT) and questionnaires were obtained from the first 15 040 participants, aged 50–64 years, of the Swedish CArdioPulmonary bioImage Study (SCAPIS). Both GLI reference values and the lambda-mu-sigma (LMS) method were used to define the LLN in asymptomatic never-smokers without respiratory disease (n=4903, of which 2329 were women).Both the median and LLN for DLCO from SCAPIS were above the median and LLN from the GLI (p<0.05). The prevalence of DLCO <GLI LLN (and also <SCAPIS LLN) was 3.9%, while the prevalence of DLCO >GLI LLN but <SCAPIS LLN was 5.7%. Subjects with DLCO >GLI LLN but <SCAPIS LLN (n=860) had more emphysema (14.3% versus 4.5%, p<0.001), chronic airflow limitation (8.5% versus 3.9%, p<0.001) and chronic bronchitis (8.3% versus 4.4%, p<0.01) than subjects (n=13 600) with normal DLCO (>GLI LLN and >SCAPIS LLN). No differences were found with regard to physician-diagnosed asthma.The GLI LLN for DLCO is lower than the estimated LLN in healthy, never-smoking, middle-aged Swedish adults. Individuals with DLCO above the GLI LLN but below the SCAPIS LLN had, to a larger extent, an increased respiratory burden. This suggests clinical implications for choosing an adequate LLN for studied populations.

scholarly journals Prediction of peak expiratory flow rate in a Ugandan population

2015 ◽  
Vol 21 (4) ◽  
pp. 96
Author(s):  
Susan Kiwanuka Nakubulwa ◽  
K Baisley ◽  
J Levin
Keyword(s):  
Lung Function ◽  
Reference Values ◽  
Regression Equations ◽  
East African ◽  
Cross Sectional ◽  
African Populations ◽  
Study Population ◽  
Males And Females ◽  
Western Uganda ◽  
Ugandan Population

<p>Background. Peak expiratory ow rate (PEFR) measurement is one of the commonly used methods for assessing lung function in general practice<br />consultations. e reference values for use by this method are mainly from Caucasian populations; data for African populations are limited. e<br />existence of ethnic and racial dierences in lung function necessitates further generation of PEFR reference values for use in African populations.<br />Objective. To generate equations for predicting PEFR in a Ugandan population.<br />Methods. e PEFR study was cross-sectional and based in rural south-western Uganda. Participants were aged 15 years or more, without respiratory<br />symptoms and were residents of the study area. Multiple regression equations for predicting PEFR were tted separately for males and females. e<br />model used for PEFR prediction was: logePEFR = intercept + a(age, y) + b(logeage) + c(1/height in cm), where a, b and c are the regression coecients.<br />Results. e eligible study population consisted of 774 males and 781 females. Median height was 164 cm (males) and 155 cm (females).<br />e majority of participants had never smoked (males 76.7%; females 98.3%). e equation which gave the best t for males was<br />logePEFR = 6.188 – 0.019age + 0.557logeage – 199.945/height and for females: logePEFR = 5.948 – 0.014 age + 0.317logeage – 85.147/height.<br />Conclusion. e curvilinear model obtained takes into consideration the changing trends of PEFR with increasing age from adolescence<br />to old age. It provides PEFR prediction equations that can be applied in East African populations.</p>

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