The Periodic Table’s Impact on Bioinorganic Chemistry and Biology’s Selective Use of Metal Ions

2019 ◽  
pp. 153-173
Author(s):  
Ambika Bhagi-Damodaran ◽  
Yi Lu
Keyword(s):  
Metal Ions ◽  
Bioinorganic Chemistry

scholarly journals Aquaporins in cancer development: opportunities for bioinorganic chemistry to contribute novel chemical probes and therapeutic agents

Metallomics ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 696-712 ◽  
Author(s):  
Brech Aikman ◽  
Andreia de Almeida ◽  
Samuel M. Meier-Menches ◽  
Angela Casini
Keyword(s):  
Hydrogen Peroxide ◽  
Metal Ions ◽  
Water Flow ◽  
Bioinorganic Chemistry ◽  
Therapeutic Agents ◽  
Cancer Development ◽  
Cellular Transport ◽  
Chemical Probes ◽  
Aquaporin Channels

Metal ions and complexes can interfere with the transcellular water flow but also with the cellular transport of glycerol and hydrogen peroxide,viainhibition of the ubiquitous aquaporin channels.

scholarly journals Transition metal complexes of phyllobilins – a new realm of bioinorganic chemistry

2015 ◽  
Vol 44 (22) ◽  
pp. 10116-10127 ◽  
Author(s):  
Chengjie Li ◽  
Bernhard Kräutler
Keyword(s):  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Photophysical Properties ◽  
Bioinorganic Chemistry ◽  
Transition Metal Ions ◽  
Natural Ligand

Phyllobilins may function as natural ligand molecules for biologically important transition metal ions, giving complexes with remarkable chemical and photophysical properties.

Metal Complexes of Biologically Important Ligands, CLXXII [1]. Metal Ions and Metal Complexes as Protective Groups of Amino Acids and Peptides – Reactions at Coordinated Amino Acids

2009 ◽  
Vol 64 (11-12) ◽  
pp. 1221-1245 ◽  
Author(s):  
Wolfgang Beck
Keyword(s):  
Organic Chemistry ◽  
Amino Acids ◽  
Metal Ions ◽  
Metal Complexes ◽  
Peptide Synthesis ◽  
Bioinorganic Chemistry ◽  
Bioorganometallic Chemistry ◽  
C Terminus ◽  
Protective Groups ◽  
Multifunctional Molecules

The introduction of protective groups into multifunctional molecules, e. g. into amino acids for peptide synthesis, and their removal are one of the most important techniques and strategies in Organic Chemistry [2]. Amino acids, their anions and derivatives are versatile ligands, and the leading idea to protect the N- or C-terminus of amino acids by metal ions or by metal complexes has opened interesting chapters which reach from classical coordination and bioinorganic chemistry to modern organometallic and bioorganometallic chemistry [3]

scholarly journals Appropriate Buffers for Studying the Bioinorganic Chemistry of Silver(I)

Chemistry ◽  
2020 ◽  
Vol 2 (1) ◽  
pp. 193-202
Author(s):  
Lucille Babel ◽  
Soledad Bonnet-Gómez ◽  
Katharina Fromm
Keyword(s):  
Metal Ions ◽  
Silver Nitrate ◽  
Thermodynamic Parameters ◽  
Sulfonic Acid ◽  
Antimicrobial Properties ◽  
Bioinorganic Chemistry ◽  
Binding Constants ◽  
Complexing Agents ◽  
Silver Cations ◽  
Micromolar Range

Silver(I) is being largely studied for its antimicrobial properties. In parallel to that growing interest, some researchers are investigating the effect of this ion on eukaryotes and the mechanism of silver resistance of certain bacteria. For these studies, and more generally in biology, it is necessary to work in buffer systems that are most suitable, i.e., that interact least with silver cations. Selected buffers such as 4-(2-hydroxyethyl)-1-piperazineethane sulfonic acid (HEPES) were therefore investigated for their use in the presence of silver nitrate. Potentiometric titrations allowed to determine stability constants for the formation of (Ag(Buffer)) complexes. The obtained values were adapted to extract the apparent binding constants at physiological pH. The percentage of metal ions bound to the buffer was calculated at this pH for given concentrations of buffer and silver to realize at which extent silver was interacting with the buffer. We found that in the micromolar range, HEPES buffer is sufficiently coordinating to silver to have a non-negligible effect on the thermodynamic parameters determined for an analyte. Morpholinic buffers were more suitable as they turned out to be weaker complexing agents. We thus recommend the use of MOPS for studies of physiological pH.

HREM Study of electron-induced surface radiation damage in ReO3

1991 ◽  
Vol 49 ◽  
pp. 636-637
Author(s):  
R. Ai ◽  
H.-J. Fan ◽  
L. D. Marks
Keyword(s):  
Transition Metal ◽  
Metal Ions ◽  
Metal Oxides ◽  
Electron Irradiation ◽  
Transition Metal Oxides ◽  
Carbon Film ◽  
Transition Metal Ions ◽  
Surface Radiation ◽  
Valence Transition ◽  
Electron Microscopes

It has been known for a long time that electron irradiation induces damage in maximal valence transition metal oxides such as TiO2, V2O5, and WO3, of which transition metal ions have an empty d-shell. This type of damage is excited by electronic transition and can be explained by the Knoteck-Feibelman mechanism (K-F mechanism). Although the K-F mechanism predicts that no damage should occur in transition metal oxides of which the transition metal ions have a partially filled d-shell, namely submaximal valence transition metal oxides, our recent study on ReO3 shows that submaximal valence transition metal oxides undergo damage during electron irradiation.ReO3 has a nearly cubic structure and contains a single unit in its cell: a = 3.73 Å, and α = 89°34'. TEM specimens were prepared by depositing dry powders onto a holey carbon film supported on a copper grid. Specimens were examined in Hitachi H-9000 and UHV H-9000 electron microscopes both operated at 300 keV accelerating voltage. The electron beam flux was maintained at about 10 A/cm2 during the observation.

ELNES of Iron Compounds

1990 ◽  
Vol 48 (2) ◽  
pp. 28-29
Author(s):  
Hiroki Kurata ◽  
Kazuhiro Nagai ◽  
Seiji Isoda ◽  
Takashi Kobayashi
Keyword(s):  
Energy Loss ◽  
Metal Ions ◽  
Energy Resolution ◽  
Transition Metal Oxides ◽  
Local Symmetry ◽  
Iron Compounds ◽  
Fine Structures ◽  
Electron Energy Loss ◽  
Fe Ions ◽  
Electron Energy Loss Spectra

Electron energy loss spectra of transition metal oxides, which show various fine structures in inner shell edges, have been extensively studied. These structures and their positions are related to the oxidation state of metal ions. In this sence an influence of anions coordinated with the metal ions is very interesting. In the present work, we have investigated the energy loss near-edge structures (ELNES) of some iron compounds, i.e. oxides, chlorides, fluorides and potassium cyanides. In these compounds, Fe ions (Fe2+ or Fe3+) are octahedrally surrounded by six ligand anions and this means that the local symmetry around each iron is almost isotropic.EELS spectra were obtained using a JEM-2000FX with a Gatan Model-666 PEELS. The energy resolution was about leV which was mainly due to the energy spread of LaB6 -filament. The threshole energies of each edges were measured using a voltage scan module which was calibrated by setting the Ni L3 peak in NiO to an energy value of 853 eV.

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