Review of the Effects of Perinatal Exposure to Endocrine-Disrupting Chemicals in Animals and Humans

2019 ◽  
pp. 131-184 ◽  
Author(s):  
William Nelson ◽  
Ying-Xiong Wang ◽  
Gloria Sakwari ◽  
Yu-Bin Ding
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Perinatal Exposure ◽  
Endocrine Disrupting

Perinatal exposure to mixtures of endocrine disrupting chemicals reduces female rat follicle reserves and accelerates reproductive aging

2016 ◽  
Vol 61 ◽  
pp. 186-194 ◽  
Author(s):  
Hanna Katarina Lilith Johansson ◽  
Pernille Rosenskjold Jacobsen ◽  
Ulla Hass ◽  
Terje Svingen ◽  
Anne Marie Vinggaard ◽  
...  
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Perinatal Exposure ◽  
Reproductive Aging ◽  
Female Rat ◽  
Endocrine Disrupting

scholarly journals Perinatal Exposure to Phthalates: From Endocrine to Neurodevelopment Effects

2021 ◽  
Vol 22 (8) ◽  
pp. 4063
Author(s):  
Laura Lucaccioni ◽  
Viola Trevisani ◽  
Erica Passini ◽  
Beatrice Righi ◽  
Carlotta Plessi ◽  
...  
Keyword(s):  
System Development ◽  
Endocrine Disrupting Chemicals ◽  
Cognitive Disorders ◽  
Perinatal Exposure ◽  
Adverse Health Outcomes ◽  
Endocrine Disrupting ◽  
And Function ◽  
The Impact ◽  
Temporal Windows

Phthalates, as other endocrine disrupting chemicals (EDCs), may alter the homeostasis and the action of hormones and signaling molecules, causing adverse health outcomes. This is true especially for infants, who are both more exposed and sensitive to their effects. Phthalates are particularly harmful when the exposure occurs during certain critical temporal windows of the development, such as the prenatal and the early postnatal phases. Phthalates may also interfere with the neuroendocrine systems (e.g., thyroid hormone signaling or metabolism), causing disruption of neuronal differentiation and maturation, increasing the risk of behavioral and cognitive disorders (ADHD and autistic behaviors, reduced mental, psychomotor, and IQ development, and emotional problems). Despite more studies being needed to better understand the role of these substances, plenty of evidence suggests the impact of phthalates on the neuroendocrine system development and function. This review aims to update the knowledge on the neuroendocrine consequences of neonatal and perinatal exposure to phthalates.

Effect of Polyphosphate on Removal of Endocrine-Disrupting Chemicals of Nonylphenol and Bisphenol-A by Activated Carbons

2005 ◽  
Vol 40 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Keun J. Choi ◽  
Sang G. Kim ◽  
Chang W. Kim ◽  
Seung H. Kim
Keyword(s):  
Activated Carbon ◽  
Bisphenol A ◽  
Surface Charge ◽  
Activated Carbons ◽  
Endocrine Disrupting Chemicals ◽  
Dipole Interaction ◽  
High Affinity ◽  
Calcium Polyphosphate ◽  
Endocrine Disrupting ◽  
Positively Charged

Abstract This study examined the effect of polyphosphate on removal of endocrine-disrupting chemicals (EDCs) such as nonylphenol and bisphenol-A by activated carbons. It was found that polyphosphate aided in the removal of nonylphenol and bisphenol- A. Polyphosphate reacted with nonylphenol, likely through dipole-dipole interaction, which then improved the nonylphenol removal. Calcium interfered with this reaction by causing competition. It was found that polyphosphate could accumulate on carbon while treating a river. The accumulated polyphosphate then aided nonylphenol removal. The extent of accumulation was dependent on the type of carbon. The accumulation occurred more extensively with the wood-based used carbon than with the coal-based used carbon due to the surface charge of the carbon. The negatively charged wood-based carbon attracted the positively charged calcium-polyphosphate complex more strongly than the uncharged coal-based carbon. The polyphosphate-coated activated carbon was also effective in nonylphenol removal. The effect was different depending on the type of carbon. Polyphosphate readily attached onto the wood-based carbon due to its high affinity for polyphosphate. The attached polyphosphate then improved the nonylphenol removal. However, the coating failed to attach polyphosphate onto the coal-based carbon. The nonylphenol removal performance of the coal-based carbon remained unchanged after the polyphosphate coating.

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