Palladium-catalyzed Reactions Using NHC Ligands

2006 ◽  
pp. 47-82 ◽  
Author(s):  
Silvia Díez-González ◽  
Steven P. Nolan
Keyword(s):  
Palladium Catalyzed ◽  
Catalyzed Reactions

A General and Simple Removal of the Allyloxycarbonyl Protecting Group by Palladium-Catalyzed Reactions Using Nitrogen and Sulfur Nucleophiles

Synlett ◽  
1993 ◽  
Vol 1993 (09) ◽  
pp. 680-682 ◽  
Author(s):  
Jean Pierre Genêt ◽  
Errol Blart ◽  
Monique Savignac ◽  
Stéphane Lemeune ◽  
Sandrine Lemaire-Audoire ◽  
...  
Keyword(s):  
Protecting Group ◽  
Palladium Catalyzed ◽  
Catalyzed Reactions

Diversity-Oriented Synthesis of Substituted Furo[2,3-b]pyrazines

2009 ◽  
Vol 62 (1) ◽  
pp. 27 ◽  
Author(s):  
Vaibhav P. Mehta ◽  
Sachin G. Modha ◽  
Denis Ermolat'ev ◽  
Kristof Van Hecke ◽  
Luc Van Meervelt ◽  
...  
Keyword(s):  
Efficient Method ◽  
Electrophilic Cyclization ◽  
Diversity Oriented Synthesis ◽  
Highly Efficient ◽  
Palladium Catalyzed ◽  
Catalyzed Reactions

A highly efficient method for the synthesis of diversely substituted furo[2,3-b]pyrazines has been elaborated. The Ag+- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)-pyrazin-2(1H)-ones affords substituted furo[2,3-b]pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b]pyrazines.

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