Growth of Hydroxyapatite Nanocrystals in Aqueous Microgels

Author(s):  
Susann Schachschal ◽  
Andrij Pich ◽  
Hans-Juergen Adler
Nanoscale ◽  
2021 ◽  
Author(s):  
Weijian Fang ◽  
Hang Ping ◽  
Wolfgang Wagermaier ◽  
Shenbao Jin ◽  
Shahrouz Amini ◽  
...  

Collagen fibrils present periodic structures, which provide space for intrafibrillar growth of oriented hydroxyapatite nanocrystals in bone and contribute to the good mechanical properties of bone. However, there are not...


2020 ◽  
Vol 7 (3) ◽  
pp. 96
Author(s):  
Despoina Brasinika ◽  
Elias P. Koumoulos ◽  
Kyriaki Kyriakidou ◽  
Eleni Gkartzou ◽  
Maria Kritikou ◽  
...  

Bioinspired scaffolds mimicking natural bone-tissue properties holds great promise in tissue engineering applications towards bone regeneration. Within this work, a way to reinforce mechanical behavior of bioinspired bone scaffolds was examined by applying a physical crosslinking method. Scaffolds consisted of hydroxyapatite nanocrystals, biomimetically synthesized in the presence of collagen and l-arginine. Scaffolds were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), microcomputed tomography, and nanoindentation. Results revealed scaffolds with bone-like nanostructure and composition, thus an inherent enhanced cytocompatibility. Evaluation of porosity proved the development of interconnected porous network with bimodal pore size distribution. Mechanical reinforcement was achieved through physical crosslinking with riboflavin irradiation, and nanoindentation tests indicated that within the experimental conditions of 45% humidity and 37 °C, photo-crosslinking led to an increase in the scaffold’s mechanical properties. Elastic modulus and hardness were augmented, and specifically elastic modulus values were doubled, approaching equivalent values of trabecular bone. Cytocompatibility of the scaffolds was assessed using MG63 human osteosarcoma cells. Cell viability was evaluated by double staining and MTT assay, while attachment and morphology were investigated by SEM. The results suggested that scaffolds provided a cell friendly environment with high levels of viability, thus supporting cell attachment, spreading and proliferation.


Author(s):  
Hossein Karampour ◽  
Mohammad Ahmadi Parsa ◽  
Ali Heidary Moghadam ◽  
Bahram Pourhasan ◽  
Rouholah Ashiri

Author(s):  
Lia Rimondini ◽  
Barbara Palazzo ◽  
Michele Iafisco ◽  
Lorenza Canegallo ◽  
Federica Demarosi ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (40) ◽  
pp. 22883-22890 ◽  
Author(s):  
Dariela Núñez ◽  
Jon Ander Serrano ◽  
Aritz Mancisidor ◽  
Elizabeth Elgueta ◽  
Kokkarachedu Varaprasad ◽  
...  

Removal of Pb(ii), Cu(ii) and Cd(ii) was attained using hydroxyapatite nanocrystals derived from clam shells, in batch and column experiments.


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