Stereotactic Body Radiotherapy

2017 ◽  
pp. 323-395
Author(s):  
Gargi Kothari ◽  
Simon S. Lo ◽  
Matthew Foote ◽  
Arjun Sahgal ◽  
Irene Karam ◽  
...  
Keyword(s):  
Stereotactic Body Radiotherapy

Sterotaktische ablative Bestrahlung (SABR): Therapieoption für ältere Patienten

2011 ◽  
Vol 02 (05) ◽  
pp. 237-238
Author(s):  
Bettina Reich
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Ältere Patienten ◽  
Supportive Therapie ◽  
Höheres Alter

Häufig weisen neudiagnostizierte NSCLC-Patienten mit einem geringen Krankheits – stadium ein höheres Alter von 75 Jahre und mehr auf. Sollte man eine Behandlung anbieten, oder sich auf eine gute supportive Therapie beschränken? Einen Ausweg aus diesem Dilemma könnte die ablative sterotaktische Bestrahlung (SABR) bieten. Diese Methode – oft auch als „stereotactic body radiotherapy” bezeichnet – kann in ambulanter Manier erfolgen und umfasst nur 3 bis 5 Bestrahlungen.

Extrakranielle Stereotaxie statt chirurgischer Resektion?

2018 ◽  
Vol 09 (02) ◽  
pp. 90-91
Author(s):  
Kretzschmar Alexander
Keyword(s):  
Stereotactic Body Radiotherapy ◽  
Ältere Patienten ◽  
National Cancer Database ◽  
Extrakranielle Stereotaxie

Ältere Patienten mit operablem nicht kleinzelligem Bronchialkarzinom (NSCLC) profitieren von einer extrakraniellen Stereotaxie (Stereotactic Body RadioTherapy; SBRT) mehr als von einer chirurgischen Resektion. In einem großen retrospektiven Propensity-gematchten und altersstratifizierten Vergleich von Patienten aus der US National Cancer Database (n = 27 200) verzeichneten die Patienten nach SBRT eine signifikant niedrigere Mortalität 30 und 90 Tage nach der Intervention (p < 0,001). Die Unterschiede waren am größten bei Patienten > 70 Jahre.

Lobectomy Versus Stereotactic Body Radiotherapy In Healthy Octogenarians With Stage I Lung Cancer

2020 ◽  
Author(s):  
Syed S. Razi ◽  
Karishma Kodia ◽  
Ahmed Alnajar ◽  
Mark I. Block ◽  
Francisco Tarrazzi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Stereotactic Body Radiotherapy ◽  
Stage I ◽  
Stage I Lung Cancer

scholarly journals Combination of the G-8 Screening Tool and Hand-Grip Strength to Predict Long-Term Overall Survival in Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3363
Author(s):  
Kristian Kirkelund Bentsen ◽  
Olfred Hansen ◽  
Jesper Ryg ◽  
Ann-Kristine Weber Giger ◽  
Stefan Starup Jeppesen
Keyword(s):  
Overall Survival ◽  
Grip Strength ◽  
Cancer Patients ◽  
Stereotactic Body Radiotherapy ◽  
Statistical Significance ◽  
Multivariable Analysis ◽  
Hand Grip Strength ◽  
Physical Test ◽  
Hand Grip

The Geriatric 8 (G-8) is a known predictor of overall survival (OS) in older cancer patients, but is mainly based on nutritional aspects. This study aimed to assess if the G-8 combined with a hand-grip strength test (HGST) in patients with NSCLC treated with stereotactic body radiotherapy can predict long-term OS better than the G-8 alone. A total of 46 SBRT-treated patients with NSCLC of stage T1-T2N0M0 were included. Patients were divided into three groups: fit (normal G-8 and HGST), vulnerable (abnormal G-8 or HGST), or frail (abnormal G-8 and HGST). Statistically significant differences were found in 4-year OS between the fit, vulnerable, and frail groups (70% vs. 46% vs. 25%, p = 0.04), as well as between the normal and abnormal G-8 groups (69% vs. 39%, p = 0.02). In a multivariable analysis of OS, being vulnerable with a hazard ratio (HR) of 2.03 or frail with an HR of 3.80 indicated poorer OS, but this did not reach statistical significance. This study suggests that there might be a benefit of adding a physical test to the G-8 for more precisely predicting overall survival in SBRT-treated patients with localized NSCLC. However, this should be confirmed in a larger study population.

Sign in / Sign up

Export Citation Format

Share Document