Radionuclide Therapy of Inflammatory Joint Diseases (Radiation Synovectomy, Radiosynoviorthesis)

2013 ◽  
pp. 459-493
Author(s):  
Gynter Mödder
Keyword(s):  
Radionuclide Therapy ◽  
Joint Diseases ◽  
Radiation Synovectomy ◽  
Inflammatory Joint Diseases

Radiation synovectomy with 90Y colloid in the therapy of recurrent knee joint effusions in patients with inflammatory joint diseases

2007 ◽  
Vol 27 (8) ◽  
pp. 729-734 ◽  
Author(s):  
Beata Chrapko ◽  
Robert Zwolak ◽  
Anna Nocuń ◽  
Renata Gołębiewska ◽  
Maria Majdan
Keyword(s):  
Knee Joint ◽  
Joint Diseases ◽  
Radiation Synovectomy ◽  
Inflammatory Joint Diseases ◽  
Joint Effusions

scholarly journals Mechanisms and Mediators of Pain in Chronic Inflammatory Arthritis

2021 ◽  
Author(s):  
Marco Di Carlo ◽  
Gianluca Smerilli ◽  
Fausto Salaffi
Keyword(s):  
Inflammatory Pain ◽  
Inflammatory Arthritis ◽  
Operational Definition ◽  
Immunosuppressive Drugs ◽  
Therapeutic Strategies ◽  
Future Research ◽  
Common Symptom ◽  
Joint Diseases ◽  
Chronic Inflammatory Arthritis ◽  
Inflammatory Joint Diseases

Abstract Purpose of the review Pain in chronic inflammatory joint diseases is a common symptom reported by patients. Pain becomes of absolute clinical relevance especially when it becomes chronic, i.e., when it persists beyond normal healing times. As an operational definition, pain is defined chronic when it lasts for more than 3 months. This article aims to provide a review of the main mechanisms underlying pain in patients with chronic inflammatory joint diseases, discussing in particular their overlap. Recent findings While it may be intuitive how synovial inflammation or enthesitis are responsible for nociceptive pain, in clinical practice, it is common to find patients who continue to complain of symptoms despite optimal control of inflammation. In this kind of patients at the genesis of pain, there may be neuropathic or nociplastic mechanisms. Summary In the context of chronic inflammatory joint diseases, multiple mechanisms generally coexist behind chronic pain. It is the rheumatologist’s task to identify the mechanisms of pain that go beyond the nociceptive mechanisms, to adopt appropriate therapeutic strategies, including avoiding overtreatment of patients with immunosuppressive drugs. In this sense, future research will have to be oriented to search for biomarkers of non-inflammatory pain in patients with chronic inflammatory joint diseases.

scholarly journals Oligonucleotide Therapies in the Treatment of Arthritis: A Narrative Review

Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 902
Author(s):  
Susanne N. Wijesinghe ◽  
Mark A. Lindsay ◽  
Simon W. Jones
Keyword(s):  
Rheumatoid Arthritis ◽  
Articular Cartilage ◽  
Joint Diseases ◽  
Synovial Joint ◽  
Pharmacological Treatments ◽  
In Vivo Models ◽  
Inflammatory Joint Diseases ◽  
Joint Pathology ◽  
Cellular Pathways

Osteoarthritis (OA) and rheumatoid arthritis (RA) are two of the most common chronic inflammatory joint diseases, for which there remains a great clinical need to develop safer and more efficacious pharmacological treatments. The pathology of both OA and RA involves multiple tissues within the joint, including the synovial joint lining and the bone, as well as the articular cartilage in OA. In this review, we discuss the potential for the development of oligonucleotide therapies for these disorders by examining the evidence that oligonucleotides can modulate the key cellular pathways that drive the pathology of the inflammatory diseased joint pathology, as well as evidence in preclinical in vivo models that oligonucleotides can modify disease progression.

Association of mastocytosis with inflammatory joint diseases: A series of 31 patients

2014 ◽  
Vol 44 (3) ◽  
pp. 362-365 ◽  
Author(s):  
Brigitte Bader-Meunier ◽  
Cristina Bulai Livideanu ◽  
Claire Larroche ◽  
Isabelle Durieu ◽  
Laure Artru ◽  
...  
Keyword(s):  
Joint Diseases ◽  
Inflammatory Joint Diseases

scholarly journals THU0140 Effects of statin-treatment on coronary plaques in patients with inflammatory joint diseases

2018 ◽  
Author(s):  
M. Svanteson ◽  
S. Rollefstad ◽  
N.E. Kløw ◽  
E. Ikdahl ◽  
J. Sexton ◽  
...  
Keyword(s):  
Statin Treatment ◽  
Joint Diseases ◽  
Inflammatory Joint Diseases
Sign in / Sign up

Export Citation Format

Share Document