scholarly journals Delta Opioid Receptor Expression and Function in Primary Afferent Somatosensory Neurons

2017 ◽  
pp. 87-114 ◽  
Author(s):  
Amaury François ◽  
Grégory Scherrer
Keyword(s):  
Opioid Receptor ◽  
Receptor Expression ◽  
Delta Opioid Receptor ◽  
Primary Afferent ◽  
Somatosensory Neurons ◽  
And Function

966 Localization and Function of Fluorescently-Tagged Delta Opioid Receptor (DOR) Expressed in Enteric Neurons of Knockin Mice

2010 ◽  
Vol 138 (5) ◽  
pp. S-142
Author(s):  
Daniel P. Poole ◽  
Juan C. Pelayo ◽  
Gregory Scherrer ◽  
Allan I. Basbaum ◽  
Brigitte L. Kieffer ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Enteric Neurons ◽  
Delta Opioid Receptor ◽  
And Function

Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity

Gut ◽  
2013 ◽  
Vol 63 (7) ◽  
pp. 1199-1200 ◽  
Author(s):  
Patrick A Hughes ◽  
Joel Castro ◽  
Andrea M Harrington ◽  
Nicole Isaacs ◽  
Melissa Moretta ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Visceral Hypersensitivity ◽  
Receptor Expression ◽  
And Function

Role of the 807 C/T Polymorphism of the α2 Gene in Platelet GP Ia Collagen Receptor Expression and Function

1999 ◽  
Vol 81 (06) ◽  
pp. 951-956 ◽  
Author(s):  
J. Corral ◽  
R. González-Conejero ◽  
J. Rivera ◽  
F. Ortuño ◽  
P. Aparicio ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Cell Types ◽  
Receptor Expression ◽  
Case Control Studies ◽  
Platelet Surface ◽  
Vitro Analysis ◽  
And Function ◽  
In Vitro Analysis

SummaryThe variability of the platelet GP Ia/IIa density has been associated with the 807 C/T polymorphism (Phe 224) of the GP Ia gene in American Caucasian population. We have investigated the genotype and allelic frequencies of this polymorphism in Spanish Caucasians. The T allele was found in 35% of the 284 blood donors analyzed. We confirmed in 159 healthy subjects a significant association between the 807 C/T polymorphism and the platelet GP Ia density. The T allele correlated with high number of GP Ia molecules on platelet surface. In addition, we observed a similar association of this polymorphism with the expression of this protein in other blood cell types. The platelet responsiveness to collagen was determined by “in vitro” analysis of the platelet activation and aggregation response. We found no significant differences in these functional platelet parameters according to the 807 C/T genotype. Finally, results from 3 case/control studies involving 302 consecutive patients (101 with coronary heart disease, 104 with cerebrovascular disease and 97 with deep venous thrombosis) determined that the 807 C/T polymorphism of the GP Ia gene does not represent a risk factor for arterial or venous thrombosis.

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