scholarly journals Organ-Specific Cancer Metabolism and Its Potential for Therapy

2015 ◽  
pp. 321-353 ◽  
Author(s):  
Ilaria Elia ◽  
Roberta Schmieder ◽  
Stefan Christen ◽  
Sarah-Maria Fendt
Keyword(s):  
Cancer Metabolism ◽  
Specific Cancer ◽  
Organ Specific

scholarly journals Tumor-on-chip modeling of organ-specific cancer and metastasis

2021 ◽  
Author(s):  
Nuala Del Piccolo ◽  
Venktesh S. Shirure ◽  
Ye Bi ◽  
S. Peter Goedegebuure ◽  
Sepideh Gholami ◽  
...  
Keyword(s):  
Specific Cancer ◽  
Organ Specific ◽  
On Chip

scholarly journals Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)

2020 ◽  
Author(s):  
Toni T. Seppälä ◽  
Mev Dominguez-Valentin ◽  
Julian R. Sampson ◽  
Pål Møller
Keyword(s):  
Lynch Syndrome ◽  
Good Prognosis ◽  
Cancer Risks ◽  
Time Intervals ◽  
Current Management ◽  
Management Guidelines ◽  
Specific Cancer ◽  
Organ Specific ◽  
And Gender ◽  
After Cancer

Abstract The Prospective Lynch Syndrome Database (PLSD) has been developed as an international, multicentre, prospective, observational study that aims to provide age and organ-specific cancer risks according to gene and gender, estimates of survival after cancer and information on the effects of interventions. Recent reports from PLSD provided improved estimates of cancer risks and survival and showed that different time intervals between surveillance colonoscopies did not affect the incidence, stage or prognosis of colorectal cancer. The PLSD reports suggest that current management guidelines for Lynch syndrome should be revised in light of the different gene and gender-specific cancer risks and the good prognosis for the most commonly associated cancers. In this review, we describe the discrepancies between the current management guidelines for Lynch Syndrome and the most recent prospective observational studies, indicating the areas of further research.

Role of Organ Specific Cancer Stem Cells in Organ Specific Cancer Progression

2020 ◽  
Vol 6 (2) ◽  
pp. 21
Author(s):  
Muhammad Ali ◽  
Fatima Ali ◽  
Nadia Wajid
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Cancer Cells ◽  
Cancer Progression ◽  
Cancer Biology ◽  
Cancer Therapeutics ◽  
Therapeutic Approaches ◽  
Specific Cancer ◽  
Organ Specific

Since the cancer stem cells (CSC) have been identified in 1997 by Bonnet and Dick, more than 100,000 papers have been published on the CSC. Huge research on cancer stem cells helped the scientists to rethink about the cancer therapeutics as classic way of chemotherapy is ineffective because chemotherapy failed to kill these cells, the only reason of cancer relapse. The cancer theory of stem cells is one of the most trending theory in stem cells and cancer biology focusing on the understanding of biology of cancer cells for an enhanced and improved therapeutic approaches should be applied to cure the cancer. This mini-review is a short overview on the role of organ specific cancer stem cells in the organ specific cancer progression.

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