Nanostructured Devices Based on Block Copolymer Assemblies for Drug Delivery: Designing Structures for Enhanced Drug Function

2005 ◽  
pp. 67-101 ◽  
Author(s):  
Nobuhiro Nishiyama ◽  
Kazunori Kataoka
Keyword(s):  
Drug Delivery ◽  
Block Copolymer

Synthesis of PMMA-b-PS Block Copolymer by Emulsion ATRP and its Self-Assembly Property

2013 ◽  
Vol 705 ◽  
pp. 115-119
Author(s):  
Bao Yong Tian ◽  
Er Jun Tang ◽  
Miao Yuan ◽  
Rui Xia Hao ◽  
Cun Man Li ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Self Assembly ◽  
Potential Application ◽  
Morphological Characteristic ◽  
Living Polymerization ◽  
The Self ◽  
Emulsion System ◽  
Copolymer Concentration ◽  
Ft Ir

The well-defined block copolymer PMMA-b-PS was prepared by two-step ATRP in emulsion system. GPC results indicate that Mn increased linearly with conversion and polydispersity remained relatively narrow. It presents the characteristics of living polymerization in emulsion system. FT-IR demonstrated that block copolymer PMMA-b-PS could be successfully synthesized by ATRP with macroinitiator PMMA-Cl in emulsion system. The morphological characteristic of the self-assembly depends on the block copolymer concentration and transforms between spheres and rodlike micelles. The property indicates a perfect potential application in drug delivery materials.

Nano-engineering block copolymer aggregates for drug delivery

1999 ◽  
Vol 16 (1-4) ◽  
pp. 3-27 ◽  
Author(s):  
Christine Allen ◽  
Dusica Maysinger ◽  
Adi Eisenberg
Keyword(s):  
Drug Delivery ◽  
Block Copolymer

Zwitterionic Block Copolymer Prodrug Micelles for pH Responsive Drug Delivery and Hypoxia-Specific Chemotherapy

2021 ◽  
Author(s):  
Jianyang Zhao ◽  
Yi-Yang Peng ◽  
Diana Diaz-Dussan ◽  
Jacinta White ◽  
Wei Duan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Ph Responsive

A Smart Drug Delivery System Based on Thermo-Responsive Polymer Gated Au NRs@SiO2 Nano-Platform

2021 ◽  
Vol 16 (7) ◽  
pp. 1029-1036
Author(s):  
Hongzhu Wang ◽  
Mengxun Chen ◽  
Liping Song ◽  
Youju Huang
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Photothermal Therapy ◽  
Drug Loading ◽  
Temperature Sensitive

A key challenge for nanoparticles-based drug delivery system is to achieve manageable drug release in tumour cell. In this study, a versatile system combining photothermal therapy and controllable drug release for tumour cells using temperature-sensitive block copolymer coupled Au NRs@SiO2 is reported. While the Au NRs serve as hyperthermal agent and the mesoporous silica was used to improve the drug loading and decrease biotoxicity. The block copolymer acted as “gatekeeper” to regulate the release of model drug (Doxorubicin hydrochloride, DOX). Through in vivo and in vitro experiments, we achieved the truly controllable drug release and photothermal therapy with the collaborative effect of the three constituents of the nanocomposites. The reported nanocomposites pave the way to high-performance controllable drug release and photothermal therapy system.

Polymerization of dopamine accompanying its coupling to induce self-assembly of block copolymer and application in drug delivery

2020 ◽  
Vol 11 (16) ◽  
pp. 2811-2821 ◽  
Author(s):  
Yudian Qiu ◽  
Zongyuan Zhu ◽  
Yalei Miao ◽  
Panke Zhang ◽  
Xu Jia ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Self Assembly ◽  
The Self ◽  
Ordered Structures

The polymerization of dopamine and its coupling occur in succession, which synergistically induces the self-assembly of block copolymer to yield ordered structures, including micelles and vesicles.

Cyclodextrin-functionalized asymmetric block copolymer films as high-capacity reservoir for drug delivery

2019 ◽  
Vol 584 ◽  
pp. 1-8 ◽  
Author(s):  
Tiefan Huang ◽  
Priyanka Manchanda ◽  
Liwen Zhang ◽  
Osama Shekhah ◽  
Niveen M. Khashab ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
High Capacity ◽  
Copolymer Films

Supramolecular micellar drug delivery system based on multi-arm block copolymer for highly effective encapsulation and sustained-release chemotherapy

2019 ◽  
Vol 7 (37) ◽  
pp. 5677-5687 ◽  
Author(s):  
Li Zhang ◽  
Dongjian Shi ◽  
Chunling Shi ◽  
Tatsuo Kaneko ◽  
Mingqing Chen
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Sustained Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Loading ◽  
High Drug ◽  
Release Drug ◽  
Drug Loading Efficiency ◽  
High Drug Loading

A novel multi-arm polyphosphoester-based nanomaterial provides high drug loading efficiency and sustained-release drug delivery for effective chemotherapy.

Block copolymer@ZIF-8 nanocomposites as a pH-responsive multi-steps release system for controlled drug delivery

2020 ◽  
Vol 31 (6) ◽  
pp. 695-711 ◽  
Author(s):  
Zhentao Lei ◽  
Qiuju Tang ◽  
Yanshan Ju ◽  
Yonghui Lin ◽  
Xiaowen Bai ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Controlled Drug Delivery ◽  
Ph Responsive ◽  
Release System
Sign in / Sign up

Export Citation Format

Share Document