Transition-Metal Catalyzed C–C Bond Formation Using Organobismuth Compounds

2011 ◽  
pp. 199-228 ◽  
Author(s):  
Shigeru Shimada ◽  
Maddali L. N. Rao
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

scholarly journals Transition Metal-Catalyzed α-Position Carbon–Carbon Bond Formations of Carbonyl Derivatives

Catalysts ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 861 ◽  
Author(s):  
Ha-Eun Lee ◽  
Dopil Kim ◽  
Ahrom You ◽  
Myung Hwan Park ◽  
Min Kim ◽  
...  
Keyword(s):  
Transition Metal ◽  
Carbonyl Compounds ◽  
Bond Formation ◽  
Chiral Ligand ◽  
Catalytic Systems ◽  
Carbon Bond ◽  
Carbonyl Derivatives ◽  
Carbon Carbon Bond ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

α-Functionalization of carbonyl compounds in organic synthesis has traditionally been accomplished via classical enolate chemistry. As α-functionalized carbonyl moieties are ubiquitous in biologically and pharmaceutically valuable molecules, catalytic α-alkylations have been extensively studied, yielding a plethora of practical and efficient methodologies. Moreover, stereoselective carbon–carbon bond formation at the α-position of achiral carbonyl compounds has been achieved by using various transition metal–chiral ligand complexes. This review describes recent advances—in the last 20 years and especially focusing on the last 10 years—in transition metal-catalyzed α-alkylations of carbonyl compounds, such as aldehydes, ketones, imines, esters, and amides and in efficient carbon–carbon bond formations. Active catalytic species and ligand design are discussed, and mechanistic insights are presented. In addition, recently developed photo-redox catalytic systems for α-alkylations are described as a versatile synthetic tool for the synthesis of chiral carbonyl-bearing molecules.

Aryl—Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation

ChemInform ◽  
2007 ◽  
Vol 38 (22) ◽  
Author(s):  
Dino Alberico ◽  
Mark E. Scott ◽  
Mark Lautens
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Direct Arylation ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Synthesis of Cyclic Peptides via Transition Metal Catalyzed C-C Bond Formation

2006 ◽  
pp. 50-52
Author(s):  
Dirk T. S. Rijkers ◽  
Hefziba T. ten Brink ◽  
Nourdin Ghalit ◽  
Jan Tois ◽  
Rob M. J. Liskamp
Keyword(s):  
Transition Metal ◽  
Cyclic Peptides ◽  
Bond Formation ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Early transition metal-catalyzed C–H alkylation: hydroaminoalkylation for Csp3–Csp3 bond formation in the synthesis of selectively substituted amines

2018 ◽  
Vol 54 (89) ◽  
pp. 12543-12560 ◽  
Author(s):  
P. M. Edwards ◽  
L. L. Schafer
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Protecting Group ◽  
Early Transition Metal ◽  
Directing Group ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Early Transition

Protecting group, directing group, and external oxidant free synthesis of structurally diverse amines.

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