scholarly journals A Complex Bio-networks of the Function Profile of Genes

Author(s):  
Charles C. H. Liu ◽  
I-Jen Chiang ◽  
Jau-Min Wong ◽  
Ginni Hsiang-Chun Tsai ◽  
Tsau Young (’T. Y. ’) Lin
Keyword(s):  
2011 ◽  
Vol 378-379 ◽  
pp. 565-568
Author(s):  
Wan Maisarah Mukhtar ◽  
P. Susthitha Menon ◽  
Sahbudin Shaari

Fraunhofer diffraction pattern from a circular aperture with the diameter of 10µm was observed using an optical fiber microprobe. The optical fiber microprobe started to detect optical power when the distance between the probe and the circular aperture was more than 292µm. When the probe was moved in a lateral motion, the light propagation showed a Bessel function profile. When the optical fiber microprobe was moved from 293µm to 309µm from the centre of the circular aperture in a transverse motion, the power detected was not consistent with a continuation of maxima and minima due to the effect of light propagation from the circular aperture. We also observed that the distance between the probe and the centre of the circular aperture was directly proportional with the radius of focused spot and inversely proportional with the Fresnel number.


2021 ◽  
pp. 20210057
Author(s):  
Amar Ajay Chotai ◽  
Dipayan Mitra

We present a 1-year-old boy who presented to the emergency department with a 7-day history of diarrhoea and vomiting. The initial renal function profile demonstrated a urea of 55 mmol l−1 (normal range between 5 and 20 mmol l−1), creatinine 695 micromol/L (normal range between 62–106 micromol/L) and potassium 9.1 mmol l−1 (normal range between 3.5–5.0 mmol l−1), with a profound metabolic acidosis. Upon examination, there were no significant findings, specifically no neurological abnormality. He was prescribed back-to-back Salbutamol nebulisers, to increase the shift of extracellular potassium into the intracellular space, followed by i.v. calcium gluconate, with some improvement in potassium levels. A further 5 mmol of sodium bicarbonate was given, as well as a stat dose of 1 mg/kg furosemide, and per rectal calcium resonium. He was then commenced on an infusion with 10% dextrose with insulin. He was subsequently found to be in urinary retention and a catheter was inserted, which drained 1700 ml. A subsequent renal function profile, 24 hours after admission, demonstrated improvement with urea 39 mmol l−1, creatinine 300 micromol/L and potassium 3.0 mEq/L.


2018 ◽  
Author(s):  
Vibhu Agarwal ◽  
Matthew Smuck ◽  
Christy Tomkins-Lane ◽  
Nigam H Shah

BACKGROUND Clinical assessments for physical function do not objectively quantify routine daily activities. Wearable activity monitors (WAMs) enable objective measurement of daily activities, but it remains unclear how these map to clinically measured physical function measures. OBJECTIVE This study aims to derive a representation of physical function from daily measurements of free-living activity obtained through a WAM. In addition, we evaluate our derived measure against objectively measured function using an ordinal classification setup. METHODS We defined function profiles representing average time spent in a set of pattern classes over consecutive days. We constructed a function profile using minute-level activity data from a WAM available from the Osteoarthritis Initiative. Using the function profile as input, we trained statistical models that classified subjects into quartiles of objective measurements of physical function as measured through the 400-m walk test, 20-m walk test, and 5 times sit-stand test. Furthermore, we evaluated model performance on held-out data. RESULTS The function profile derived from minute-level activity data can accurately predict physical performance as measured through clinical assessments. Using held-out data, the Goodman-Kruskal Gamma statistic obtained in classifying performance values in the first quartile, interquartile range, and the fourth quartile was 0.62, 0.53, and 0.51 for the 400-m walk, 20-m walk, and 5 times sit-stand tests, respectively. CONCLUSIONS Function profiles accurately represent physical function, as demonstrated by the relationship between the profiles and clinically measured physical performance. The estimation of physical performance through function profiles derived from free-living activity data may enable remote functional monitoring of patients.


2018 ◽  
Vol 136 (1) ◽  
pp. 111-125 ◽  
Author(s):  
Andreas Zellner ◽  
Eva Scharrer ◽  
Thomas Arzberger ◽  
Chio Oka ◽  
Valérie Domenga-Denier ◽  
...  

2020 ◽  
Vol 80 ◽  
pp. 101846
Author(s):  
Ellen C. Litkowski ◽  
Jennifer K. Finders ◽  
Giulia A. Borriello ◽  
David J. Purpura ◽  
Sara A. Schmitt

2011 ◽  
Vol 18 (3) ◽  
pp. 249-257 ◽  
Author(s):  
Abeer Attia Saad ◽  
Eman Abdel Rahman Ismail ◽  
Yasser Wagih Darwish ◽  
Hesham Ahmed Nasr ◽  
Abdel Rahman Hassan ◽  
...  

2009 ◽  
Vol 104 ◽  
pp. S488 ◽  
Author(s):  
Reza Hejazi ◽  
Teri Lavenbarg ◽  
Mazen Dimachkie ◽  
Mamatha Pasnoor ◽  
Laura Herbelin ◽  
...  

2003 ◽  
Vol 109 (5) ◽  
pp. 809-830 ◽  
Author(s):  
H. Abe ◽  
T. Higaki ◽  
T. Kobayashi

Sign in / Sign up

Export Citation Format

Share Document