Protein Stability Engineering in Staphylococcal Nuclease Using an AI-Neural Network Hybrid System and a Genetic Algorithm

Author(s):  
Christopher M. Frenz
2000 ◽  
Vol 176 ◽  
pp. 135-136
Author(s):  
Toshiki Aikawa

AbstractSome pulsating post-AGB stars have been observed with an Automatic Photometry Telescope (APT) and a considerable amount of precise photometric data has been accumulated for these stars. The datasets, however, are still sparse, and this is a problem for applying nonlinear time series: for instance, modeling of attractors by the artificial neural networks (NN) to the datasets. We propose the optimization of data interpolations with the genetic algorithm (GA) and the hybrid system combined with NN. We apply this system to the Mackey–Glass equation, and attempt an analysis of the photometric data of post-AGB variables.


Author(s):  
Carlos Alberto Reyes-García ◽  
Sandra E. Barajas ◽  
Esteban Tlelo-Cuautle ◽  
Orion Fausto Reyes-Galaviz

Automatic Infant Cry Recognition (AICR) process is basically a problem of pattern processing, very similar to the Automatic Speech Recognition (ASR) process (Huang, Acero, Hon, 2001). In AICR first we perform acoustical analysis, where the crying signal is analyzed to extract the more important acoustical features, like; LPC, MFCC, etc. (Cano, Escobedo and Coello, 1999). The obtained characteristics are represented by feature vectors, and each vector represents a pattern. These patterns are then classified in their corresponding pathology (Ekkel, 2002). In the reported case we are automatically classifying cries from normal, deaf and asphyxiating infants. We use a genetic algorithm to find several optimal parameters needed by the Fuzzy Relational Neural Network FRNN (Reyes, 1994), like; the number of linguistic properties, the type of membership function, the method to calculate the output and the learning rate. The whole model has been tested on several data sets for infant cry classification. The process, as well as some results, is described.


Author(s):  
Renqiang Wang ◽  
Qinrong Li ◽  
Shengze Miao ◽  
Keyin Miao ◽  
Hua Deng

Abstract: The purpose of this paper was to design an intelligent controller of ship motion based on sliding mode control with a Radial Basis Function (RBF) neural network optimized by the genetic algorithm and expansion observer. First, the improved genetic algorithm based on the distributed genetic algorithm with adaptive fitness and adaptive mutation was used to automatically optimize the RBF neural network. Then, with the compensation designed by the RBF neural network, anti-saturation control was realized. Additionally, the intelligent control algorithm was introduced by Sliding Mode Control (SMC) with the stability theory. A comparative study of sliding mode control integrated with the RBF neural network and proportional–integral–derivative control combined with the fuzzy optimization model showed that the stabilization time of the intelligent control system was 43.75% faster and the average overshoot was reduced by 52% compared with the previous two attempts. Background: It was known that the Proportional-Integral-Derivative (PID) control and self-adaptation control cannot really solve the problems of frequent disturbance from external wind and waves, as well as the problems with ship nonlinearity and input saturation. So, the previous ship motion controller should be transformed by advanced intelligent technology, on the basis of referring to the latest relevant patent design methods. Objective: An intelligent controller of ship motion was designed based on optimized Radial Basis Function Neural Network (RBFNN) in the presence of non-linearity, uncertainty, and limited input. Methods: The previous ship motion controller was remodeled based on Sliding Mode Control (SMC) with RBFNN optimized by improved genetic algorithm and expansion observer. The intelligent control algorithm integrated with genetic neural network solved the problem of system model uncertainty, limited control input, and external interference. Distributed genetic with adaptive fitness and adaptive mutation method guaranteed the adequacy of search and the global optimal convergence results, which enhanced the approximation ability of RBFNN. With the compensation designed by the optimized RBFNN, it was realized anti-saturation control. The chattering caused by external disturbance in SMC controller was reduced by the expansion observer. Results: A comparative study with RBFNN-SMC control and fuzzy-PID control, the stabilization time of the intelligent control system was 43.75% faster, the average overshoot was reduced by 52%, compared to the previous two attempts. Conclusion: The intelligent control algorithm succeed in dealing with the problems of nonlinearity, uncertainty, input saturation, and external interference. The intelligent control algorithm can be applied into research and development ship steering system, which would be created a new patent.


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