Knowledge Discovery in Life Science Literature

Patterns ◽  
2021 ◽  
pp. 100290
Author(s):  
Vineeth Venugopal ◽  
Sourav Sahoo ◽  
Mohd Zaki ◽  
Manish Agarwal ◽  
Nitya Nand Gosvami ◽  
...  

2013 ◽  
Vol 18 (9-10) ◽  
pp. 428-434 ◽  
Author(s):  
Ian Harrow ◽  
Wendy Filsell ◽  
Peter Woollard ◽  
Ian Dix ◽  
Michael Braxenthaler ◽  
...  

2012 ◽  
Vol 24 (2-3) ◽  
pp. 195-207 ◽  
Author(s):  
Lawrence Dooley ◽  
David Kirk ◽  
Kevin Philpott

2010 ◽  
Vol 15 (6) ◽  
pp. 709-715 ◽  
Author(s):  
Yan Wang ◽  
Cong Wang ◽  
Yi Zeng ◽  
Zhisheng Huang ◽  
Vassil Momtchev ◽  
...  

Author(s):  
He Tan ◽  
Vaida Jakonienė ◽  
Patrick Lambrix ◽  
Johan Aberg ◽  
Nahid Shahmehri

2008 ◽  
Vol 2 (1) ◽  
pp. 28-36 ◽  
Author(s):  
Karl Kugler ◽  
Maria Mercedes Tejada ◽  
Christian Baumgartner ◽  
Bernhard Tilg ◽  
Armin Graber ◽  
...  

In this work we present an application for integrating and analyzing life science data using a biomedical data warehouse system and tools developed in-house enabling knowledge discovery tasks. Knowledge discovery is known as a process where different steps have to be coupled in order to solve a specified question. In order to create such a combination of steps, a data miner using our in-house developed knowledge discovery tool KD3 is able to assemble functional objects to a data mining workflow. The generated workflows can easily be used for ulterior purposes by only adding new data and parameterizing the functional objects in the process. Workflows guide the performance of data integration and aggregation tasks, which were defined and implemented using a public available open source tool. To prove the concept of our application, intelligent query models were designed and tested for the identification of genotype-phenotype correlations in Marfan Syndrome. It could be shown that by using our application, a data miner can easily develop new knowledge discovery algorithms that may later be used to retrieve medical relevant information by clinical researchers.


Author(s):  
Gustavo A. Schwartz

AbstractIn the last 2 decades, a great amount of work has been done on data mining and knowledge discovery using complex networks. These works have provided insightful information about the structure and evolution of scientific activity, as well as important biomedical discoveries. However, interdisciplinary knowledge discovery, including disciplines other than science, is more complicated to implement because most of the available knowledge is not indexed. Here, a new method is presented for mining Wikipedia to unveil implicit interdisciplinary knowledge to map and understand how different disciplines (art, science, literature) are related to and interact with each other. Furthermore, the formalism of complex networks allows us to characterise both individual and collective behaviour of the different elements (people, ideas, works) within each discipline and among them. The results obtained agree with well-established interdisciplinary knowledge and show the ability of this method to boost quantitative studies. Note that relevant elements in different disciplines that rarely directly refer to each other may nonetheless have many implicit connections that impart them and their relationship with new meaning. Owing to the large number of available works and to the absence of cross-references among different disciplines, tracking these connections can be challenging. This approach aims to bridge this gap between the large amount of reported knowledge and the limited human capacity to find subtle connections and make sense of them.


2009 ◽  
Vol 25 (23) ◽  
pp. 3194-3196 ◽  
Author(s):  
R. Easty ◽  
N. Nikolov

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