Efficient Processing of Ordered XML Twig Pattern

Author(s):  
Jiaheng Lu ◽  
Tok Wang Ling ◽  
Tian Yu ◽  
Changqing Li ◽  
Wei Ni
2009 ◽  
Vol 10 (12) ◽  
pp. 1769-1783 ◽  
Author(s):  
Jin-hua Jiang ◽  
Ke Chen ◽  
Xiao-yan Li ◽  
Gang Chen ◽  
Li-dan Shou

2009 ◽  
Vol 52 (10) ◽  
pp. 1830-1847 ◽  
Author(s):  
JunFeng Zhou ◽  
XiaoFeng Meng ◽  
TokWang Ling

2019 ◽  
Vol 13 (5) ◽  
pp. 796-802
Author(s):  
Jiping Zheng ◽  
Shunqing Jiang ◽  
Jialiang Chen ◽  
Wei Yu

2020 ◽  
Vol 117 (38) ◽  
pp. 23982-23990 ◽  
Author(s):  
Shengjun Li ◽  
Mu Li ◽  
Kan Liu ◽  
Huimin Zhang ◽  
Shuxin Zhang ◽  
...  

MAC5 is a component of the conserved MOS4-associated complex. It plays critical roles in development and immunity. Here we report that MAC5 is required for microRNA (miRNA) biogenesis. MAC5 interacts with Serrate (SE), which is a core component of the microprocessor that processes primary miRNA transcripts (pri-miRNAs) into miRNAs and binds the stem-loop region of pri-miRNAs. MAC5 is essential for both the efficient processing and the stability of pri-miRNAs. Interestingly, the reduction of pri-miRNA levels inmac5is partially caused by XRN2/XRN3, the nuclear-localized 5′-to-3′ exoribonucleases, and depends on SE. These results reveal that MAC5 plays a dual role in promoting pri-miRNA processing and stability through its interaction with SE and/or pri-miRNAs. This study also uncovers that pri-miRNAs need to be protected from nuclear RNA decay machinery, which is connected to the microprocessor.


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