Alternative Sources of Adult Stem Cells: Human Amniotic Membrane

2010 ◽  
pp. 1-27 ◽  
Author(s):  
Susanne Wolbank ◽  
Martijn Griensven ◽  
Regina Grillari-Voglauer ◽  
Anja Peterbauer-Scherb
Keyword(s):  
Stem Cells ◽  
Amniotic Membrane ◽  
Adult Stem Cells ◽  
Human Amniotic Membrane ◽  
Alternative Sources

scholarly journals Human Amniotic Membrane as a Matrix for Endothelial Differentiation of VEGF-Treated Dental Stem Cells

2019 ◽  
Vol 12 (6) ◽  
pp. 599-613 ◽  
Author(s):  
Siti Nurnasihah Md Hashim ◽  
Muhammad Fuad Hilmi Yusof ◽  
Wafa’ Zahari ◽  
Hamshawagini Chandra ◽  
Khairul Bariah Ahmad Amin Noordin ◽  
...  
Keyword(s):  
Stem Cells ◽  
Amniotic Membrane ◽  
Endothelial Differentiation ◽  
Human Amniotic Membrane ◽  
Dental Stem Cells

scholarly journals Human amniotic mesenchymal stem cells to promote/suppress cancer: two sides of the same coin

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ameneh Jafari ◽  
Mostafa Rezaei-Tavirani ◽  
Behrouz Farhadihosseinabadi ◽  
Hakimeh Zali ◽  
Hassan Niknejad
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cancer Treatment ◽  
Cancer Progression ◽  
Adult Stem Cells ◽  
Treatment Modalities ◽  
Human Amniotic Membrane ◽  
Amniotic Mesenchymal Stem Cells ◽  
Growth And Aging

AbstractCancer is a leading cause of death in both developed and developing countries, and because of population growth and aging, it is a growing medical burden worldwide. With robust development in medicine, the use of stem cells has opened new treatment modalities in cancer therapy. In adult stem cells, mesenchymal stem cells (MSCs) are showing rising promise in cancer treatment due to their unique properties. Among different sources of MSCs, human amniotic fluid/membrane is an attractive and suitable reservoir. There are conflicting opinions about the role of human amniotic membrane/fluid mesenchymal stem cells (hAMSCS/hAFMSCs) in cancer, as some studies demonstrating the anticancer effects of these cells and others suggesting their progressive effects on cancer. This review focuses on recent findings about the role of hAMSCs/hAFMSCs in cancer treatment and summarizes the suppressing as well as promoting effects of these cells on cancer progression and underling mechanisms.

scholarly journals Amniotic Fluid Cells, Stem Cells, and p53: Can We Stereotype p53 Functions?

2019 ◽  
Vol 20 (9) ◽  
pp. 2236 ◽  
Author(s):  
Melissa Rodrigues ◽  
Christine Blattner ◽  
Liborio Stuppia
Keyword(s):  
Stem Cells ◽  
Amniotic Fluid ◽  
Adult Stem Cells ◽  
Tumor Formation ◽  
Human Stem Cells ◽  
Human Amniotic Fluid ◽  
Amniotic Fluid Stem Cells ◽  
Differentiated Cells ◽  
High Proliferation Rate ◽  
Alternative Sources

In recent years, great interest has been devoted to finding alternative sources for human stem cells which can be easily isolated, ideally without raising ethical objections. These stem cells should furthermore have a high proliferation rate and the ability to differentiate into all three germ layers. Amniotic fluid, ordinarily discarded as medical waste, is potentially such a novel source of stem cells, and these amniotic fluid derived stem cells are currently gaining a lot of attention. However, further information will be required about the properties of these cells before they can be used for therapeutic purposes. For example, the risk of tumor formation after cell transplantation needs to be explored. The tumor suppressor protein p53, well known for its activity in controlling Cell Prolif.eration and cell death in differentiated cells, has more recently been found to be also active in amniotic fluid stem cells. In this review, we summarize the major findings about human amniotic fluid stem cells since their discovery, followed by a brief overview of the important role played by p53 in embryonic and adult stem cells. In addition, we explore what is known about p53 in amniotic fluid stem cells to date, and emphasize the need to investigate its role, particularly in the context of cell tumorigenicity.

scholarly journals Anti-Inflammatory and Anti-Fibrotic Effects of Human Amniotic Membrane Mesenchymal Stem Cells and Their Potential in Corneal Repair

2018 ◽  
Vol 7 (12) ◽  
pp. 906-917 ◽  
Author(s):  
Alejandro Navas ◽  
Fátima Sofía Magaña-Guerrero ◽  
Alfredo Domínguez-López ◽  
César Chávez-García ◽  
Graciela Partido ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Anti Inflammatory

scholarly journals Health Span-Extending Activity of Human Amniotic Membrane- and Adipose Tissue-Derived Stem Cells in F344 Rats

2015 ◽  
Vol 4 (10) ◽  
pp. 1144-1154 ◽  
Author(s):  
Dajeong Kim ◽  
Jangbeen Kyung ◽  
Dongsun Park ◽  
Ehn-Kyoung Choi ◽  
Kwang Sei Kim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Health Span ◽  
F344 Rats

Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy

2017 ◽  
Vol 12 (4) ◽  
pp. 1062-1073 ◽  
Author(s):  
Aure Despeyroux ◽  
Cédric Duret ◽  
Claire Gondeau ◽  
Esther Perez‐Gracia ◽  
Lisa Chuttoo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Regeneration ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Extended Hepatectomy
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