Optical Inline Measurement Procedures for Counting and Sizing Cells in Bioprocess Technology

Author(s):  
Guido Rudolph ◽  
Patrick Lindner ◽  
Arne Bluma ◽  
Klaus Joeris ◽  
Geovanni Martinez ◽  
...  
2006 ◽  
Vol 35 (10) ◽  
pp. 439-446 ◽  
Author(s):  
Z. B. Xu ◽  
L. F. Feng ◽  
G. H. Hu ◽  
X. B. Song ◽  
X. M. Zhang ◽  
...  

Author(s):  
Frank Euring ◽  
Winfried Russ ◽  
Uwe Grupa

The main objective of this work was to determine if it is possible to distinguish between intact and destroyed apple tissue with an inductively working coil system. With conductive measurement, it is possible to measure the amount of destroyed cell in plant tissues. Destroyed cells in plant tissue can mean bad quality for the particular product. The advantage of the inductive measuring technique is the possibility to measure the complete product contactless and non-destructively during the production process. Hence, an inline measurement system could be developed.In order to destroy cells in apples, a freeze-thaw cycle was subjected to three different apples varieties (Braeburn, Jonagold and Idared). The changes of the electrical parameters were observed before and after the thermal treatment.It could be demonstrated that the inductive measuring leads to similar statements as conductive measuring methods. The electrical parameters showed mass dependent. Hence, the electrical parameters had to be normalized to the sample mass. The mass normalized voltage UB,normalized is well suited to describe the cell destruction. It could be shown that the cell destruction provides higher UB,normalized-values.


Author(s):  
Matthias Bordron ◽  
Charyar Mehdi-Souzani ◽  
Olivier Bruneau

Additive manufacturing takes a growing place in industry tanks to its ability to create free-form parts with internal complex shape. Yet, the quality of the final surfaces of the additive manufacturing parts is still a challenge since it doesn’t reach the required level for final use. To address this issue, it is necessary to measure the form and dimension deviation in order to plan post-process operations to be considerate. Moreover in a context of industry 4.0, this measurement step should be fully integrated into the manufacturing line as close as possible to the additive manufacturing process and post-process. We introduce in this article an inline measurement solution based on a robot combined with a laser sensor. Robot allows reaching most of the orientation and positions necessary to digitize complex parts in a short time. The use of robot for digitizing is already addressed but not for metrological applications. Robots are perfectly designed for velocity, ability and robustness but their poor positioning accuracy is not compatible with measuring requirements. The strategy adopted in this article is to provide an algorithm to generate path planning for digitizing additive manufacturing parts at a given quality of the resulting cloud of points. After a discussion about the geometric and elastic model of the robot to identify the one that answers the quality requirements, the performances of the robot are evaluated. Thus, several performances maps are introduced to characterize the behavior of the robot in its working volume. The qualification of the digitizing sensor is also performed to identify relation between digitizing parameters and the quality of final cloud of points. Using data resulting from the qualifications of sensor and robot and the parts CAD model, the algorithm allows generating path planning to ensure the final quality necessary to measure the shape deviation.


2013 ◽  
Vol 769 ◽  
pp. 27-33 ◽  
Author(s):  
Matthäus Brela ◽  
Hans-Jörg Gebhardt

Abstract. The technical parameters of magnetic actuators, such as electromagnets, resonance actuators, reluctance actuators etc., are determined by the magnetic properties of the materials as well as the manufacturing and the design configuration. Some exemplary defects in electromagnetic actuators due to the manufacturing are heterogeneous magnetic properties of the materials, cracks, defects and parasitic air gaps in and directly around the magnetic circuit. To implement inline measurement systems to characterise defects within the manufacturing process a study has been carried out to display the influences of production impacts on magnetic stray fields outside the magnetic circuit.


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