Coordinating Multiple Droplets in Planar Array Digital Microfluidics System

Author(s):  
Eric Griffith ◽  
Srinivas Akella
2020 ◽  
Vol 27 ◽  
Author(s):  
Yi Zhang

: Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis. Compared to other microfluidic systems, magnetic digital microfluidics demonstrate compelling advantages for POC diagnostics. In this review, we have examined the capability of magnetic digital microfluidics-based POC diagnostic platforms. More importantly, we have categorized POC settings into three classes based on “where is the point”, “who to care” and “how to test”, and evaluated the suitability of magnetic digital microfluidics in various POC settings. Furthermore, we have addressed other technical issues associated with POC testing such as controlled environment, sample-system interface, system integration and information connectivity. We hope this review would provide a guideline for the future development of magnetic digital microfluidics-based platforms for POC testing.


2021 ◽  
Vol 11 (9) ◽  
pp. 4251
Author(s):  
Jinsong Zhang ◽  
Shuai Zhang ◽  
Jianhua Zhang ◽  
Zhiliang Wang

In the digital microfluidic experiments, the droplet characteristics and flow patterns are generally identified and predicted by the empirical methods, which are difficult to process a large amount of data mining. In addition, due to the existence of inevitable human invention, the inconsistent judgment standards make the comparison between different experiments cumbersome and almost impossible. In this paper, we tried to use machine learning to build algorithms that could automatically identify, judge, and predict flow patterns and droplet characteristics, so that the empirical judgment was transferred to be an intelligent process. The difference on the usual machine learning algorithms, a generalized variable system was introduced to describe the different geometry configurations of the digital microfluidics. Specifically, Buckingham’s theorem had been adopted to obtain multiple groups of dimensionless numbers as the input variables of machine learning algorithms. Through the verification of the algorithms, the SVM and BPNN algorithms had classified and predicted the different flow patterns and droplet characteristics (the length and frequency) successfully. By comparing with the primitive parameters system, the dimensionless numbers system was superior in the predictive capability. The traditional dimensionless numbers selected for the machine learning algorithms should have physical meanings strongly rather than mathematical meanings. The machine learning algorithms applying the dimensionless numbers had declined the dimensionality of the system and the amount of computation and not lose the information of primitive parameters.


Electronics ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1311
Author(s):  
Giovanni Andrea Casula ◽  
Giuseppe Mazzarella ◽  
Giorgio Montisci ◽  
Giacomo Muntoni

Planar waveguide slot arrays (WSAs) have been used since 1940 and are currently used as performing antennas for high frequencies, especially in applications such as communication and RADAR systems. We present in this work a review of the most typical waveguide slot array configurations proposed in the literature, describing their main limitations and drawbacks along with possible effective countermeasures. Our attention has been focused mainly on the improved available design techniques to obtain high performance WSAs. In particular, the addressed topics have been reported in the following. Partially filled WSAs, or WSAs covered with single or multilayer dielectric slabs, are discussed. The most prominent second-order effects in the planar array feeding network are introduced and accurately modeled. The attention is focused on the T-junction feeding the array, on the effect of interaction between each slot coupler of the feeding network and the radiating slots nearest to this coupler, and on the waveguide bends. All these effects can critically increase the first sidelobes if compared to the ideal case, causing a sensible worsening in the performance of the array.


Lab on a Chip ◽  
2021 ◽  
Author(s):  
Chin Hong Ooi ◽  
Raja Vadivelu ◽  
Jing Jin ◽  
Sreejith Kamalalayam Rajan ◽  
Pradip Singha ◽  
...  

Liquid marbles are droplets with volume typically on the order of microliters coated with hydrophobic powder. The versatility, ease of use and low cost make liquid marbles an attractive platform...


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