Hydroxylated Polychlorinated Biphenyl Metabolites Are Anti-estrogenic in a Stably Transfected Human Breast Adenocarcinoma (MCF7) Cell Line

1997 ◽  
Vol 144 (2) ◽  
pp. 363-376 ◽  
Author(s):  
Vincent J Kramer ◽  
William G Helferich ◽  
Åke Bergman ◽  
Eva Klasson-Wehler ◽  
John P Giesy
2021 ◽  
Vol 36 (1) ◽  
pp. 1029-1047
Author(s):  
Myriam González ◽  
María Ovejero-Sánchez ◽  
Alba Vicente-Blázquez ◽  
Manuel Medarde ◽  
Rogelio González-Sarmiento ◽  
...  

2019 ◽  
Vol 17 (1) ◽  
pp. 943-954
Author(s):  
Abeer N. Al-romaizan ◽  
Thoraya S. Jaber ◽  
Nesreen S. Ahmed

AbstractA series of new 2-phenyl-7-methyl-1,8-naphthyridine derivatives with variable substituents at C3 were synthesized for an in vitro evaluation of their anticancer activity against human breast cancer cell line (MCF7). On one hand, compounds 3f, 6f, 8c, and 10b showed IC50 values (6.53, 7.88, 7.89, 7.79 μM, respectively) compared to that of the mentioned drug staurosparine (IC50 = 4.51 μM). On the other hand, derivatives 10c, 8d, 4d, 10f and 8b displayed better activity than staurosporin with IC50 values (1.47, 1.62, 1.68, 2.30, 3.19 μM, respectively).


2017 ◽  
Vol 88 ◽  
pp. 34-42 ◽  
Author(s):  
Mansoor Aletaha ◽  
Behzad Mansoori ◽  
Ali Mohammadi ◽  
Mehdi Fazeli ◽  
Behzad Baradaran

In Vitro ◽  
1983 ◽  
Vol 19 (8) ◽  
pp. 635-641 ◽  
Author(s):  
James M. Bowen ◽  
Relda Cailleau ◽  
Beppino C. Giovanella ◽  
Sen Pathak ◽  
Michael J. Siciliano

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