Strain Distribution Pattern (SDP)

2001 ◽  
pp. 1889
Author(s):  
L. Silver
1993 ◽  
Vol 4 (3) ◽  
pp. 148-152 ◽  
Author(s):  
Jian-Long Mu ◽  
J�rgen K. Naggert ◽  
Patsy M. Nishina ◽  
Yin-Chai Cheah ◽  
Beverly Paigen

1990 ◽  
Vol 171 (5) ◽  
pp. 1469-1483 ◽  
Author(s):  
A A Scalzo ◽  
N A Fitzgerald ◽  
A Simmons ◽  
A B La Vista ◽  
G R Shellam

The genetic basis of the control of acute splenic MCMV infection was studied after intraperitoneal inoculation of the virus. Classical Mendelian analyses using C57BL/6 (resistant) and BALB/c (susceptible) parental strains disclosed an autosomal dominant non-H-2 gene that regulates splenic virus replication. The probable location of this gene, to which we have assigned the symbol Cmv-1, is on chromosome 6 as defined by the strain distribution pattern of splenic MCMV replication in CXB recombinant inbred mice. Although there is a similar hierarchy of resistance to MCMV and HSV-1 with respect to the C57BL and BALB genetic backgrounds, the strain distribution pattern of HSV-1 replication in recombinant inbred mice suggests that Cmv-1 is not involved in restricting the spread of this virus. This is the first clear identification of a non-H-2 gene regulating the magnitude of MCMV infection. Elucidation of the function of this gene may be a fundamental step towards understanding the control of systemic CMV infection.


2004 ◽  
Vol 172 (8) ◽  
pp. 5047-5055 ◽  
Author(s):  
Chun Xie ◽  
Ruchi Sharma ◽  
Hongwei Wang ◽  
Xin J. Zhou ◽  
Chandra Mohan

1996 ◽  
Vol 7 (7) ◽  
pp. 526-532 ◽  
Author(s):  
K. L. Shultz ◽  
K. L. Svenson ◽  
Y. -C. Cheah ◽  
B. Paigen ◽  
W. G. Beamer

1995 ◽  
Vol 6 (12) ◽  
pp. 867-872 ◽  
Author(s):  
K. L. Svenson ◽  
Y. C. Cheah ◽  
K. L. Shultz ◽  
J. L. Mu ◽  
B. Paigen ◽  
...  

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