Robust Regression for the Detection of Independent 3D Motion by a Binocular Observer

1998 ◽  
Vol 4 (2) ◽  
pp. 125-141 ◽  
Author(s):  
Antonis A. Argyros ◽  
Panos E. Trahanias ◽  
Stelios C. Orphanoudakis
Keyword(s):  
Robust Regression ◽  
3D Motion

Gender differences in the Achilles tendon load during the fencing lunge

2014 ◽  
Vol 6 (3) ◽  
Author(s):  
Jonathan Kenneth Sinclair ◽  
Lindsay Bottoms
Keyword(s):  
Gender Differences ◽  
Achilles Tendon ◽  
Motion Capture ◽  
Tendon Injury ◽  
Force Platform ◽  
Motion Capture System ◽  
3D Motion ◽  
Loading Rates ◽  
Tendon Pathology ◽  
3D Motion Capture

AbstractRecent epidemiological analyses in fencing have shown that injuries and pain linked specifically to fencing training/competition were evident in 92.8% of fencers. Specifically the prevalence of Achilles tendon pathology has increased substantially in recent years, and males have been identified as being at greater risk of Achilles tendon injury compared to their female counterparts. This study aimed to examine gender differences in Achilles tendon loading during the fencing lunge.Achilles tendon load was obtained from eight male and eight female club level epee fencers using a 3D motion capture system and force platform information as they completed simulated lunges. Independent t-tests were performed on the data to determine whether differences existed.The results show that males were associated with significantly greater Achilles tendon loading rates in comparison to females.This suggests that male fencers may be at greater risk from Achilles tendon pathology as a function of fencing training/ competition.

Common Genetic Variants in ABO and CLEC4M Modulate the Pharmacokinetics of Recombinant FVIII in Severe Hemophilia A Patients

2020 ◽  
Vol 120 (10) ◽  
pp. 1395-1406 ◽  
Author(s):  
Iris Garcia-Martínez ◽  
Nina Borràs ◽  
Marta Martorell ◽  
Rafael Parra ◽  
Carme Altisent ◽  
...  
Keyword(s):  
Blood Group ◽  
Half Life ◽  
Robust Regression ◽  
Hemophilia A ◽  
Illumina Miseq ◽  
Activity Levels ◽  
Severe Hemophilia ◽  
Single Nucleotide Variants ◽  
Common Genetic Variants ◽  
Recombinant Fviii

AbstractThe pharmacokinetic (PK) response of severe hemophilia A (HA) patients to infused factor VIII (FVIII) shows substantial variability. Several environmental and genetic factors are associated with changes in FVIII plasma levels and infused FVIII PK. Based on the hypothesis that factors influencing endogenous FVIII can affect FVIII PK, the contribution of single-nucleotide variants (SNVs) in candidate genes was investigated in 51 severe HA patients. The effects of blood group, F8 variant type, von Willebrand factor antigen and activity levels, age, and weight were also explored. The myPKFiT device was used to estimate individual PK parameters, and SNVs and clinically reportable F8 variants were simultaneously analyzed in an Illumina MiSeq instrument, using the microfluidics-based Fluidigm Access Array system. The contribution of SNVs to FVIII half-life and clearance was addressed by robust regression modeling, taking into account other modulators. In line with previous studies, we provide robust evidence that age, body weight, and blood group, as well as SNVs in ABO and CLEC4M, participate in the variability of FVIII PK in HA patients. Main results: each copy of the rs7853989 (ABO) allele increases FVIII half-life by 1.4 hours (p = 0.0131) and decreases clearance by 0.5 mL/h/kg (p = 5.57E-03), whereas each additional rs868875 (CLEC4M) allele reduces FVIII half-life by 1.1 hours (p = 2.90E-05) and increases clearance by 0.3 mL/h/kg (p = 1.01E-03). These results contribute to advancing efforts to improve FVIII replacement therapies by adjusting to each patient's PK profile based on pharmacogenomic data. This personalized medicine will decrease the burden of treatment and maximize the benefits obtained.

scholarly journals The change of gait analysis on applying metatarsal-bar used 3D motion analysis

2014 ◽  
Vol 7 (S1) ◽  
Author(s):  
Se won Yoon ◽  
Jeong woo Lee ◽  
Soo ji Park ◽  
Woong sik Park ◽  
Moon jeong Kim
Keyword(s):  
Gait Analysis ◽  
Motion Analysis ◽  
3D Motion ◽  
3D Motion Analysis

Integrated 3D motion analysis with functional magnetic resonance neuroimaging to identify neural correlates of lower extremity movement

2021 ◽  
Vol 355 ◽  
pp. 109108
Author(s):  
Manish Anand ◽  
Jed A. Diekfuss ◽  
Alexis B. Slutsky-Ganesh ◽  
Dustin R. Grooms ◽  
Scott Bonnette ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Lower Extremity ◽  
Motion Analysis ◽  
Neural Correlates ◽  
Functional Magnetic Resonance ◽  
3D Motion ◽  
3D Motion Analysis
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