Bacterial Expression and Purification of the Fab Fragment of a Monoclonal Antibody Specific for the Low-Density Lipoprotein Receptor-Binding Site of Human Apolipoprotein E

Robert Raffaı̈; Jelena Vukmirica; Karl H. Weisgraber; Eric Rassart; Thomas L. Innerarity; Ross Milne

doi:10.1006/prep.1999.1031

Bacterial Expression and Purification of the Fab Fragment of a Monoclonal Antibody Specific for the Low-Density Lipoprotein Receptor-Binding Site of Human Apolipoprotein E

Protein Expression and Purification ◽

10.1006/prep.1999.1031 ◽

1999 ◽

Vol 16 (1) ◽

pp. 84-90 ◽

Cited By ~ 10

Author(s):

Robert Raffaı̈ ◽

Jelena Vukmirica ◽

Karl H. Weisgraber ◽

Eric Rassart ◽

Thomas L. Innerarity ◽

...

Keyword(s):

Monoclonal Antibody ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Expression And Purification ◽

Fab Fragment ◽

Receptor Binding Site ◽

Human Apolipoprotein ◽

Density Lipoprotein Receptor

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Does the EcoRI polymorphism in the human apolipoprotein B gene affect the binding of low density lipoprotein to the low density lipoprotein receptor?

Arteriosclerosis and Thrombosis A Journal of Vascular Biology ◽

10.1161/01.atv.12.2.256 ◽

1992 ◽

Vol 12 (2) ◽

pp. 256-260 ◽

Cited By ~ 10

Author(s):

J J Gallagher ◽

N B Myant

Keyword(s):

Apolipoprotein B ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Human Apolipoprotein ◽

Density Lipoprotein Receptor ◽

Apolipoprotein B Gene

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Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

Journal of Clinical Investigation ◽

10.1172/jci1847 ◽

1998 ◽

Vol 101 (5) ◽

pp. 1084-1093 ◽

Cited By ~ 147

Author(s):

J Boren ◽

I Lee ◽

W Zhu ◽

K Arnold ◽

S Taylor ◽

...

Keyword(s):

Receptor Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Binding Activity ◽

Carboxyl Terminus ◽

Low Density ◽

Lipoprotein Receptor ◽

Receptor Binding Site ◽

Apolipoprotein B100 ◽

Density Lipoprotein Receptor

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Conservation of the low density lipoprotein receptor-binding domain of apoprotein B. Demonstration by a new monoclonal antibody, MB47.

Arteriosclerosis An Official Journal of the American Heart Association Inc ◽

10.1161/01.atv.6.2.178 ◽

1986 ◽

Vol 6 (2) ◽

pp. 178-188 ◽

Cited By ~ 99

Author(s):

S G Young ◽

J L Witztum ◽

D C Casal ◽

L K Curtiss ◽

S Bernstein

Keyword(s):

Monoclonal Antibody ◽

Receptor Binding ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Receptor Binding Domain ◽

Low Density Lipoprotein Receptor ◽

Apoprotein B ◽

Density Lipoprotein Receptor

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Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: No accentuation by apolipoprotein(a)

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.95.8.4544 ◽

1998 ◽

Vol 95 (8) ◽

pp. 4544-4549 ◽

Cited By ~ 103

Author(s):

D. A. Sanan ◽

D. L. Newland ◽

R. Tao ◽

S. Marcovina ◽

J. Wang ◽

...

Keyword(s):

Apolipoprotein B ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Chow Diet ◽

Low Density ◽

Lipoprotein Receptor ◽

Human Apolipoprotein ◽

Atherosclerotic Lesions ◽

Apolipoprotein A ◽

Density Lipoprotein Receptor

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Mutation of the Low Density Lipoprotein Receptor in Homozygous Familial Hypercholesterolemia: Analysis by Monoclonal Antibody

The Journal of Japan Atherosclerosis Society ◽

10.5551/jat1973.15.4_929 ◽

1987 ◽

Vol 15 (4) ◽

pp. 929-933

Author(s):

Tohru FUNAHASHI ◽

Yasuko MIYAKE ◽

Taku YAMAMURA ◽

Akira YAMAMOTO ◽

Shizuya YAMASHITA ◽

...

Keyword(s):

Monoclonal Antibody ◽

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Homozygous Familial Hypercholesterolemia ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Monoclonal antibody 5A binds apolipoprotein B-48 and inhibits the low density lipoprotein-receptor interaction

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(89)90758-4 ◽

1989 ◽

Vol 162 (3) ◽

pp. 908-915 ◽

Cited By ~ 2

Author(s):

Alberto Corsini ◽

Simona Fantappiè ◽

Santica Marcovina ◽

Agnese Granata ◽

Remo Fumagalli ◽

...

Keyword(s):

Monoclonal Antibody ◽

Apolipoprotein B ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Receptor Interaction ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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OS076. The effect of lectin-like oxidized low density lipoprotein receptor monoclonal antibody (LOX-1 MAb) on the expression of eNOS in preeclamptic HUVECs model

Pregnancy Hypertension ◽

10.1016/j.preghy.2012.04.077 ◽

2012 ◽

Vol 2 (3) ◽

pp. 218-219 ◽

Cited By ~ 2

Author(s):

K. Keman ◽

B. Rahardjo ◽

D. Madakusuma

Keyword(s):

Monoclonal Antibody ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Oxidized Low Density Lipoprotein ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Receptor Monoclonal Antibody

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Epitopes close to the apolipoprotein B low density lipoprotein receptor-binding site are modified by advanced glycation end products

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.95.13.7643 ◽

1998 ◽

Vol 95 (13) ◽

pp. 7643-7647 ◽

Cited By ~ 27

Author(s):

X. Wang ◽

R. Bucala ◽

R. Milne

Keyword(s):

Apolipoprotein B ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Advanced Glycation ◽

Receptor Binding Site ◽

Glycation End Products ◽

End Products ◽

Density Lipoprotein Receptor

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In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.

Journal of Clinical Investigation ◽

10.1172/jci119036 ◽

1996 ◽

Vol 98 (10) ◽

pp. 2259-2267 ◽

Cited By ~ 77

Author(s):

M C Jong ◽

V E Dahlmans ◽

P J van Gorp ◽

K W van Dijk ◽

M L Breuer ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hepatic Uptake ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Receptor Associated Protein ◽

Human Apolipoprotein ◽

Density Lipoprotein Receptor

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Baculovirus-mediated expression of human apolipoprotein E in Manduca sexta larvae generates particles that bind to the low density lipoprotein receptor.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.19.8530 ◽

1991 ◽

Vol 88 (19) ◽

pp. 8530-8533 ◽

Cited By ~ 23

Author(s):

D. G. Gretch ◽

S. L. Sturley ◽

P. D. Friesen ◽

N. E. Beckage ◽

A. D. Attie

Keyword(s):

Apolipoprotein E ◽

Manduca Sexta ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Human Apolipoprotein ◽

Density Lipoprotein Receptor ◽

Manduca Sexta Larvae

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