Catalytic and Cytotoxic Activities of Recombinant Ricin A Chain Mutants with Charged Residues Added at the Carboxyl Terminus

J.C. Simpson; L.M. Roberts; J.M. Lord

doi:10.1006/prep.1995.1087

Catalytic and Cytotoxic Activities of Recombinant Ricin A Chain Mutants with Charged Residues Added at the Carboxyl Terminus

Protein Expression and Purification ◽

10.1006/prep.1995.1087 ◽

1995 ◽

Vol 6 (5) ◽

pp. 665-670 ◽

Cited By ~ 7

Author(s):

J.C. Simpson ◽

L.M. Roberts ◽

J.M. Lord

Keyword(s):

Carboxyl Terminus ◽

Cytotoxic Activities ◽

Ricin A Chain ◽

Charged Residues ◽

A Chain ◽

Ricin A

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A highly cytotoxic human transferrin-ricin A chain conjugate used to select receptor-modified cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)43579-4 ◽

1984 ◽

Vol 259 (2) ◽

pp. 1143-1149 ◽

Cited By ~ 6

Author(s):

V Raso ◽

M Basala

Keyword(s):

Ricin A Chain ◽

Human Transferrin ◽

A Chain ◽

Ricin A

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Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)80482-7 ◽

1993 ◽

Vol 268 (32) ◽

pp. 23986-23990

Author(s):

R Wales ◽

L.M. Roberts ◽

J.M. Lord

Keyword(s):

Endoplasmic Reticulum ◽

Mammalian Cells ◽

Ricin A Chain ◽

A Chain ◽

Ricin A

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Purification and characterization of trichosanthin. Homology to the ricin A chain and implications as to mechanism of abortifacient activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)60855-5 ◽

1987 ◽

Vol 262 (24) ◽

pp. 11628-11633

Author(s):

J M Maraganore ◽

M Joseph ◽

M C Bailey

Keyword(s):

Purification And Characterization ◽

Ricin A Chain ◽

A Chain ◽

Ricin A

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An anti-mucin immunotoxin BrE-3-ricin A-chain is potently and selectively toxic to human small-cell lung cancer

Lung Cancer ◽

10.1016/0169-5002(93)90362-2 ◽

1993 ◽

Vol 10 (1-2) ◽

pp. 130

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

Ricin A Chain ◽

A Chain ◽

Ricin A

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Free Energy Determinants of Binding the rRNA Substrate and Small Ligands to Ricin A-Chain

Biophysical Journal ◽

10.1016/s0006-3495(99)77175-4 ◽

1999 ◽

Vol 76 (1) ◽

pp. 28-39 ◽

Cited By ~ 26

Author(s):

Mark A. Olson ◽

Lilee Cuff

Keyword(s):

Free Energy ◽

Ricin A Chain ◽

A Chain ◽

Ricin A ◽

Small Ligands

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Characterization of the increased cytotoxicity of gelonin anti-T cell immunoconjugates compared with ricin A chain immunoconjugates

Clinical & Experimental Immunology ◽

10.1111/j.1365-2249.1994.tb06572.x ◽

2008 ◽

Vol 97 (1) ◽

pp. 10-18 ◽

Cited By ~ 4

Author(s):

D. M. FISHWILD ◽

H.-M. WU ◽

S. F. CARROLL ◽

S. L. BERNHARD

Keyword(s):

T Cell ◽

Ricin A Chain ◽

A Chain ◽

Ricin A

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Toxicity of ligand and antibody-directed ricin A-chain conjugates recognizing the epidermal growth factor receptor

Journal of Cellular Physiology ◽

10.1002/jcp.1041310314 ◽

1987 ◽

Vol 131 (3) ◽

pp. 418-425 ◽

Cited By ~ 31

Author(s):

Angelika M. Vollmar ◽

Deborah E. Banker ◽

John Mendelsohn ◽

Harvey R. Herschman

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Ricin A Chain ◽

Epidermal Growth ◽

A Chain ◽

Ricin A

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Involvement of arginine residues in inhibition of protein synthesis by ricin A-chain

FEBS Letters ◽

10.1016/0014-5793(86)80815-8 ◽

1986 ◽

Vol 204 (2) ◽

pp. 219-222 ◽

Cited By ~ 14

Author(s):

Keiichi Watanabe ◽

Gunki Funatsu

Keyword(s):

Protein Synthesis ◽

Ricin A Chain ◽

Inhibition Of Protein Synthesis ◽

Arginine Residues ◽

A Chain ◽

Ricin A

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A hypothesis to explain the substrate reactivity of ribosomal and stem-loop RNA with ricin A-chain

Toxicon ◽

10.1016/s0041-0101(96)00102-x ◽

1996 ◽

Vol 34 (11-12) ◽

pp. 1317-1324 ◽

Cited By ~ 3

Author(s):

Todd Link ◽

Xiang Yang Chen ◽

Lin Hao Niu ◽

Vern L. Schramm

Keyword(s):

Ricin A Chain ◽

Stem Loop ◽

Substrate Reactivity ◽

A Chain ◽

Ricin A

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Site-directed mutagenesis of ricin A chain Trp 211 to Phe

International journal of peptide & protein research ◽

10.1111/j.1399-3011.1990.tb00062.x ◽

2009 ◽

Vol 35 (4) ◽

pp. 365-366 ◽

Cited By ~ 11

Author(s):

JANICE L. BRADLEY ◽

PETER M. McGUIRE

Keyword(s):

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Ricin A Chain ◽

A Chain ◽

Ricin A

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