The Role of Prefrontal Cortex in Sensory Memory and Motor Preparation: An Event-Related fMRI Study

NeuroImage ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. 400-408 ◽  
Author(s):  
M. D'Esposito ◽  
D. Ballard ◽  
E. Zarahn ◽  
G.K. Aguirre
Keyword(s):  
Prefrontal Cortex ◽  
Motor Preparation ◽  
Sensory Memory ◽  
Fmri Study

scholarly journals The Role of the Prefrontal Cortex in Recognition Memory and Memory for Source: An fMRI Study

NeuroImage ◽  
1999 ◽  
Vol 10 (5) ◽  
pp. 520-529 ◽  
Author(s):  
Michael D. Rugg ◽  
Paul C. Fletcher ◽  
Phyllis M-L. Chua ◽  
Raymond J. Dolan
Keyword(s):  
Prefrontal Cortex ◽  
Recognition Memory ◽  
Fmri Study

Comparison of abstract decision encoding in the monkey prefrontal cortex, the presupplementary, and cingulate motor areas

2013 ◽  
Vol 110 (1) ◽  
pp. 19-32 ◽  
Author(s):  
Katharina Merten ◽  
Andreas Nieder
Keyword(s):  
Prefrontal Cortex ◽  
Cognitive Processing ◽  
Planning Process ◽  
Motor Planning ◽  
Motor Preparation ◽  
Neuron Activity ◽  
Critical Element ◽  
Cingulate Motor Area ◽  
Monkey Prefrontal Cortex

Deciding between alternatives is a critical element of flexible behavior. Perceptual decisions have been studied extensively in an action-based framework. Recently, we have shown that abstract perceptual decisions are encoded in prefrontal cortex (PFC) neurons ( Merten and Nieder 2012 ). However, the role of other frontal cortex areas remained elusive. Here, we trained monkeys to perform a rule-based visual detection task that disentangled abstract perceptual decisions from motor preparation. We recorded the single-neuron activity in the presupplementary (preSMA) and the rostral part of the cingulate motor area (CMAr) and compared it to the results previously found in the PFC. Neurons in both areas traditionally identified with motor planning process the abstract decision independently of any motor preparatory activity by similar mechanisms as the PFC. A larger proportion of decision neurons and a higher strength of decision encoding was found in the preSMA than in the PFC. Neurons in both areas reliably predicted the monkeys' decisions. The fraction of CMAr decision neurons and their strength of the decision encoding were comparable to the PFC. Our findings highlight the role of both preSMA and CMAr in abstract cognitive processing and emphasize that both frontal areas encode decisions prior to the preparation of a motor output.

Intact Proactive Motor Inhibition after Unilateral Prefrontal Cortex or Basal Ganglia Lesions

2021 ◽  
pp. 1-18
Author(s):  
Matthias Liebrand ◽  
Anne-Kristin Solbakk ◽  
Ingrid Funderud ◽  
Macià Buades-Rotger ◽  
Robert T. Knight ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Basal Ganglia ◽  
Contingent Negative Variation ◽  
Motor Preparation ◽  
Motor Inhibition ◽  
Critical Importance ◽  
Electrophysiological Activity ◽  
Preparatory Attention ◽  
External Signals

Previous research provided evidence for the critical importance of the prefrontal cortex (pFC) and basal ganglia (BG) for reactive motor inhibition, that is, when actions are cancelled in response to external signals. Less is known about the role of the pFC and BG in proactive motor inhibition, referring to preparation for an upcoming stop signal. In this study, patients with unilateral lesions to the BG or lateral pFC performed in a cued go/no-go task, whereas their EEG was recorded. The paradigm called for cue-based preparation for upcoming, lateralized no-go signals. Based on previous findings, we focused on EEG indices of cognitive control (prefrontal beta), motor preparation (sensorimotor mu/beta, contingent negative variation [CNV]), and preparatory attention (occipital alpha, CNV). On a behavioral level, no differences between patients and controls were found, suggesting an intact ability to proactively prepare for motor inhibition. Patients showed an altered preparatory CNV effect, but no other differences in electrophysiological activity related to proactive and reactive motor inhibition. Our results suggest a context-dependent role of BG and pFC structures in motor inhibition, being critical in reactive, unpredictable contexts, but less so in situations where one can prepare for stopping on a short timescale.

scholarly journals Cerebral responses and role of the prefrontal cortex in conditioned pain modulation: an fMRI study in healthy subjects

2015 ◽  
Vol 281 ◽  
pp. 187-198 ◽  
Author(s):  
Volodymyr B. Bogdanov ◽  
Alessandro Viganò ◽  
Quentin Noirhomme ◽  
Olena V. Bogdanova ◽  
Nathalie Guy ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Healthy Subjects ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Fmri Study

scholarly journals A key role of the prefrontal cortex in the maintenance of chronic tinnitus: An fMRI study using a Stroop task

2018 ◽  
Vol 17 ◽  
pp. 325-334 ◽  
Author(s):  
Rodrigo Araneda ◽  
Laurent Renier ◽  
Laurence Dricot ◽  
Monique Decat ◽  
Daniela Ebner-Karestinos ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Stroop Task ◽  
Chronic Tinnitus ◽  
Fmri Study

Specific role of medial prefrontal cortex in retrieving recent autobiographical memories: An fMRI study of young female subjects

Cortex ◽  
2010 ◽  
Vol 46 (1) ◽  
pp. 29-39 ◽  
Author(s):  
Silvia Oddo ◽  
Silke Lux ◽  
Peter H. Weiss ◽  
Anna Schwab ◽  
Harald Welzer ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Medial Prefrontal Cortex ◽  
Young Female ◽  
Specific Role ◽  
Autobiographical Memories ◽  
Fmri Study ◽  
Female Subjects

On the role of the anterior prefrontal cortex in cognitive ‘branching’: An fMRI study

2015 ◽  
Vol 77 ◽  
pp. 421-429 ◽  
Author(s):  
George Chahine ◽  
Esther Kristina Diekhof ◽  
Alexandra Tinnermann ◽  
Oliver Gruber
Keyword(s):  
Prefrontal Cortex ◽  
Fmri Study ◽  
Anterior Prefrontal Cortex
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