Oxidant Stress: The Role of the Glutathione Redox Cycle in Skin Preconditioning

1995 ◽  
Vol 58 (4) ◽  
pp. 395-400 ◽  
Author(s):  
Riley S. Rees ◽  
David J. Smith ◽  
Belinda Adamson ◽  
Michael Im ◽  
Daniel Hinshaw
Keyword(s):  
Oxidant Stress ◽  
Redox Cycle ◽  
Glutathione Redox Cycle ◽  
Glutathione Redox

Role of glutathione redox cycle in TNF-α-mediated endothelial cell dysfunction

1995 ◽  
Vol 117 (2) ◽  
pp. 179-188 ◽  
Author(s):  
Michal Toborek ◽  
Steven W. Barger ◽  
Mark P. Mattson ◽  
Craig J. McClain ◽  
Bernhard Hennig
Keyword(s):  
Endothelial Cell ◽  
Redox Cycle ◽  
Endothelial Cell Dysfunction ◽  
Cell Dysfunction ◽  
Glutathione Redox Cycle ◽  
Tnf Α ◽  
Glutathione Redox

In vitro toxicity of hydrogen peroxide against normal vs. tumor rat hepatocytes: Role of catalase and of the glutathione redox cycle

Hepatology ◽  
1988 ◽  
Vol 8 (6) ◽  
pp. 1673-1678 ◽  
Author(s):  
Philippe Mavier ◽  
Bernard Guigui ◽  
Anne-Marie Preaux ◽  
Jean Rosenbaum ◽  
Marie-Claude Lescs ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Rat Hepatocytes ◽  
In Vitro Toxicity ◽  
Redox Cycle ◽  
Glutathione Redox Cycle ◽  
Glutathione Redox

Role of small heat shock protein HSP25 in radioresistance and glutathione-redox cycle

2000 ◽  
Vol 183 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Sun-Hee Baek ◽  
Jin-Na Min ◽  
Eun-Mi Park ◽  
Mi-Young Han ◽  
Yun-Sil Lee ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Small Heat Shock Protein ◽  
Redox Cycle ◽  
Glutathione Redox Cycle ◽  
Glutathione Redox

Role of iron and glutathione redox cycle in acetaminophen-induced cytotoxicity to cultured rat hepatocytes

1994 ◽  
Vol 39 (6) ◽  
pp. 1257-1264 ◽  
Author(s):  
Yasuaki Ito ◽  
Yasunaga Suzuki ◽  
Hijiri Ogonuki ◽  
Hideyuki Hiraishi ◽  
Mahnaz Razandi ◽  
...  
Keyword(s):  
Rat Hepatocytes ◽  
Redox Cycle ◽  
Glutathione Redox Cycle ◽  
Cultured Rat Hepatocytes ◽  
Glutathione Redox

Role of the glutathione redox cycle in acquired and de novo multidrug resistance

Science ◽  
1988 ◽  
Vol 241 (4866) ◽  
pp. 694-697 ◽  
Author(s):  
R. Kramer ◽  
J Zakher ◽  
G Kim
Keyword(s):  
Multidrug Resistance ◽  
De Novo ◽  
Redox Cycle ◽  
Glutathione Redox Cycle ◽  
Glutathione Redox

Platelets attenuate oxidant-induced permeability in endothelial monolayers: glutathione-dependent mechanisms

1996 ◽  
Vol 81 (4) ◽  
pp. 1701-1706 ◽  
Author(s):  
Charlie Strange ◽  
Andrew Gottehrer ◽  
Karen Birmingham ◽  
John E. Heffner
Keyword(s):  
Glucose Oxidase ◽  
Oxidant Stress ◽  
Buthionine Sulfoximine ◽  
Human Platelets ◽  
Protective Effects ◽  
Redox Cycle ◽  
Endothelial Monolayers ◽  
Glutathione Redox Cycle ◽  
Monolayer Permeability ◽  
Glutathione Redox

Strange, Charlie, Andrew Gottehrer, Karen Birmingham, and John E. Heffner. Platelets attenuate oxidant-induced permeability in endothelial monolayers: glutathione-dependent mechanisms. J. Appl. Physiol. 81(4): 1701–1706, 1996.—We studied the effects of adding washed human platelets or platelets with nonintact glutathione redox cycles to endothelial cell monolayers treated with glucose oxidase to initiate oxidant stress and increase permeability. Changes in125I-labeled albumin transmonolayer movement were used as the index of monolayer permeability. Washed human platelets attenuated oxidant-induced increases in albumin flux. Platelets treated with 1,3-bis(2-chloroethyl)-1-nitrosurea, 1-chloro-2,4-dinitrobenzene, or buthionine sulfoximine to inhibit selective enzymatic steps in the glutathione redox cycle decreased permeability to a lesser degree. We conclude that 1) washed human platelets attenuate monolayer permeability defects in aortic endothelial monolayers exposed to glucose oxidase and 2) the protective effects of platelets are partially dependent on an intact platelet glutathione redox cycle.

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