Effect of mutations in the mu-host junction region on transpososome assembly

2001 ◽  
Vol 310 (2) ◽  
pp. 299-309 ◽  
Author(s):  
Colin J Coros ◽  
George Chaconas
Keyword(s):  
Junction Region ◽  
Transpososome Assembly

The rupture process and aftershock distribution of the 6 April 1992 MS 6.8 earthquake, Offshore British Columbia

1995 ◽  
Vol 85 (3) ◽  
pp. 716-735 ◽  
Author(s):  
John F. Cassidy ◽  
Garry C. Rogers
Keyword(s):  
Surface Waves ◽  
Triple Junction ◽  
Rupture Process ◽  
Body Waves ◽  
Ocean Bottom Seismometer ◽  
Strain Accumulation ◽  
Transform Fault ◽  
Junction Region ◽  
Long Period ◽  
Initial Rupture

Abstract On 6 April 1992, a magnitude 6.8 (MS) earthquake occurred in the triple-junction region at the northern end of the Cascadia subduction zone. This was the largest earthquake in at least 75 yr to occur along the 110-km-long Revere-Dellwood-Wilson (RDW) transform fault and the first large earthquake in this region recorded by modern broadband digital seismic networks. It thus provides an opportunity to examine the rupture process along a young (<2 Ma) oceanic transform fault and to gain better insight into the tectonics of this triple-junction region. We have investigated the source parameters and the rupture process of this earthquake by modeling broadband body waves and long-period surface waves and by accurately locating the mainshock and the first 10 days of aftershocks using a well-located “calibration” event recorded during an ocean-bottom seismometer survey. Analysis of P and SH waveforms reveals that this was a complex rupture sequence consisting of three strike-slip subevents in 12 sec. The initial rupture occurred 5 to 6 km to the SW of the seafloor trace of the RDW fault at 50.55° N, 130.46° W. The dominant subevent occurred 2 to 3 sec later and 4.3 km beneath the seafloor trace of the RDW fault, and a third subevent occurred 5 sec later, 18 km to the NNW, suggesting a northwestward propagating rupture. The aftershock sequence extended along a 60- to 70-km-long segment of the RDW fault, with the bulk of the activity concentrated ∼30 to 40 km to the NNW of the epicenter, consistent with this interpretation. The well-constrained mechanism of the initial rupture (strike/dip/slip 339°/90°/−168°) and of the largest aftershock (165°/80°/170°) are rotated 15° to 20° clockwise relative to the seafloor trace of the RDW fault but are parallel to the Pacific/North America relative plate motion vector. In contrast, the mechanisms of the dominant subevent (326°/87°/−172°), and the long-period solution derived from surface waves aligns with the RDW fault. This suggests that small earthquakes (M < 6) in this area occur along faults that are optimally aligned with respect to the regional stress field, whereas large earthquakes, involving tens of kilometers of rupture, activate the RDW fault. For the mainshock, we estimate a seismic moment (from surface waves) of 1.0 × 1026 dyne-cm, a stress drop of 60 bars, and an average slip of 1.2 m. This represents only 21 yr of strain accumulation, implying that there is either a significant amount of aseismic slip along the RDW fault or that much of the strain accumulation manifests itself as deformation within the Dellwood and Winona blocks or along the continental margin.

scholarly journals Molecular analysis of the dengue virus type 1 and 2 in Brazil based on sequences of the genomic envelope-nonstructural protein 1 junction region

2004 ◽  
Vol 46 (3) ◽  
pp. 145-152 ◽  
Author(s):  
Cecília Luiza S. Santos ◽  
Maria Anice M. Sallum ◽  
Peter G. Foster ◽  
Iray Maria Rocco
Keyword(s):  
Sequence Data ◽  
Nonstructural Protein ◽  
Phylogenetic Analyses ◽  
Decomposition Analysis ◽  
Structural Protein ◽  
Network Graph ◽  
Junction Region ◽  
Split Decomposition ◽  
Genotype Iii ◽  
Nonstructural Protein 1

The genomic sequences of the Envelope-Non-Structural protein 1 junction region (E/NS1) of 84 DEN-1 and 22 DEN-2 isolates from Brazil were determined. Most of these strains were isolated in the period from 1995 to 2001 in endemic and regions of recent dengue transmission in São Paulo State. Sequence data for DEN-1 and DEN-2 utilized in phylogenetic and split decomposition analyses also include sequences deposited in GenBank from different regions of Brazil and of the world. Phylogenetic analyses were done using both maximum likelihood and Bayesian approaches. Results for both DEN-1 and DEN-2 data are ambiguous, and support for most tree bipartitions are generally poor, suggesting that E/NS1 region does not contain enough information for recovering phylogenetic relationships among DEN-1 and DEN-2 sequences used in this study. The network graph generated in the split decomposition analysis of DEN-1 does not show evidence of grouping sequences according to country, region and clades. While the network for DEN-2 also shows ambiguities among DEN-2 sequences, it suggests that Brazilian sequences may belong to distinct subtypes of genotype III.

Photoluminescence as a tool for investigations of the junction region in Cu(In,Ga)Se2-based solar cells

2011 ◽  
Vol 519 (21) ◽  
pp. 7328-7331 ◽  
Author(s):  
M. Pawlowski ◽  
P. Zabierowski ◽  
R. Bacewicz ◽  
H. Marko ◽  
N. Barreau
Keyword(s):  
Solar Cells ◽  
Junction Region

scholarly journals Synthetic peptides homologous to human glycophorins of the Miltenberger complex of variants of MNSs blood group system specify the epitopes for Hil, SJL, Hop, and Mur antisera

Blood ◽  
1991 ◽  
Vol 78 (9) ◽  
pp. 2456-2461 ◽  
Author(s):  
KK Johe ◽  
V Vengelen-Tyler ◽  
R Leger ◽  
OO Blumenfeld
Keyword(s):  
Blood Group ◽  
Blood Cells ◽  
Blood Group System ◽  
Junction Region ◽  
Group System ◽  
Erythrocyte Surface ◽  
Mnss Blood Groups ◽  
The Common ◽  
Expressed Sequence ◽  
Antigenic Epitopes

Abstract The antigenic epitopes of the MNSs blood groups are localized on alpha and delta glycophorins (glycophorins A and B) of the erythrocyte surface. Hil, SJL, Mur, and Hop antisera define the Miltenberger (Mi) complex of MiV, MiJ.L., MiIII, and MiVI variant serologic phenotypes of this blood group system. We report here the location of the epitopes for antibodies in these antisera. The antigens of these Mi classes are variant glycophorins that are hybrids of alpha and delta glycophorins in alpha-delta and delta-alpha-delta arrangements. The hybrid junctions give rise to novel polypeptide sequences not present in the parent glycophorins; in MiIII and MiVI this also includes an expressed sequence of the delta pseudoexon. These sequences are identical in the above Mi-glycophorins occurring in erythrocytes that share a common Mi determinant. Four peptides of 10 to 14 amino acids each were constructed to be homologous to the identical sequences; they were designated, “Hil”, “SJL”, “Mur”, and “Hop” to reflect the common determinant. The peptides were tested for inhibition of reaction of appropriate cells with the relevant antisera. The Hil peptide, outlining the alpha-delta s junction region in MiIII, MiV, and MiVI glycophorins, inhibited the reaction of respective erythrocytes (red blood cells [RBCs]) with anti-Hil. The SJL peptide, which differs from the Hil peptide by a single Thr----Met substitution, was specific for inhibition of the reaction of MiJ.L. RBCs with anti-SJL (an example of anti-S specific for such RBCs). The Hop peptide, which corresponds to the delta-alpha junction in MiVI glycophorin, inhibited the hemagglutination of MiVIII RBCs by anti-Hop. MiVI and MiVIII glycophorins share an identical sequence at that site. The Mur peptide, corresponding to a portion of the expressed pseudoexon sequence in MiIII and MiVI glycophorins, was specific for inhibition of the reaction of MiIII and MiVI RBCs with anti-Mur. The peptides had no effect on the hemagglutination of control MNSs RBCs by their respective antisera nor of unrelated Mi classes RBCs by antisera that distinguish these classes. We conclude that the alpha-delta junction in MiIII, MiV, and MiVI glycophorins outlines the epitopes for anti-Hil, the alpha- delta junction in MiJ.L. outlines the epitope for anti-SJL, the delta- alpha junction in MiVI constitutes the epitope for anti-Hop, and the expressed delta pseudoexon sequence in MiIII and MiVI constitutes the epitope for anti-Mur.

scholarly journals Microstructure Characteristics and Its Effect on the Fracture in the Triple Junction Region of Friction Stir Welded Mg Alloys Subjected to Tension

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3672
Author(s):  
Guodong Liu ◽  
Qunying Yang ◽  
Yongshan Cheng
Keyword(s):  
Triple Junction ◽  
Weld Zone ◽  
Base Material ◽  
Junction Region ◽  
Friction Stir ◽  
Microstructure Characteristics ◽  
Transverse Tension ◽  
Twin Band ◽  
Zone Edge ◽  
Electron Back Scattered Diffraction

Because of the tensile strength decreasing of the friction stir welded wrought magnesium (Mg) alloy compared to the base material, the reasons for the failure of weld has been focused on. After the fracture in transverse tension, the crack went through the welded joint from the center of the weld to the transition zone between the thermal-mechanical affected zone and weld zone. In the present study, the microstructure characteristics and its effect on the facture in the triple junction region is investigated. Based on the metallography and the electron back-scattered diffraction (EBSD) technology, it was observed that a twin band extended from the triple junction region to the middle of weld. The profuse twinning in the twin band was considered to play an important role on the crack propagation from the stir zone edge to the crown zone.

Recent Geodetic Results in the Azores Triple Junction Region

2004 ◽  
Vol 161 (3) ◽  
pp. 683-699 ◽  
Author(s):  
R. M. S. Fernandes ◽  
L. Bastos ◽  
B. A. C. Ambrosius ◽  
R. Noomen ◽  
S. Matheussen ◽  
...  
Keyword(s):  
Triple Junction ◽  
Junction Region ◽  
Azores Triple Junction

Bump and Trench Modifications to Film-Cooling Holes at the Vane-Endwall Junction

2008 ◽  
Vol 130 (4) ◽  
Author(s):  
N. Sundaram ◽  
K. A. Thole
Keyword(s):  
Film Cooling ◽  
Large Scale ◽  
Leading Edge ◽  
High Heat ◽  
Junction Region ◽  
High Heat Transfer ◽  
Turbine Vane ◽  
Cooling Hole ◽  
Adiabatic Effectiveness ◽  
Film Cooling Holes

The endwall of a first-stage vane experiences high heat transfer and low adiabatic effectiveness levels because of high turbine operating temperatures and formation of leading edge vortices. These vortices lift the coolant off the endwall and pull the hot mainstream gases toward it. The region of focus for this study is the vane-endwall junction region near the stagnation location where cooling is very difficult. Two different film-cooling hole modifications, namely, trenches and bumps, were evaluated to improve the cooling in the leading edge region. This study uses a large-scale turbine vane cascade with a single row of axial film-cooling holes at the leading edge of the vane endwall. Individual hole trenches and row trenches were placed along the complete row of film-cooling holes. Two-dimensional semi-elliptically shaped bumps were also evaluated by placing the bumps upstream and downstream of the film-cooling row. Tests were carried out for different trench depths and bump heights under varying blowing ratios. The results indicated that a row trench placed along the row of film-cooling holes showed a greater enhancement in adiabatic effectiveness levels when compared to individual hole trenches and bumps. All geometries considered produced an overall improvement to adiabatic effectiveness levels.

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