Ph-dependent interactions and the stability and folding kinetics of the N-terminal domain of L9. electrostatic interactions are only weakly formed in the transition state for folding 1 1Edited by C. R. Matthews

2000 ◽  
Vol 299 (4) ◽  
pp. 1091-1100 ◽  
Author(s):  
Donna L Luisi ◽  
Daniel P Raleigh
Keyword(s):  
Transition State ◽  
Electrostatic Interactions ◽  
Folding Kinetics ◽  
Terminal Domain ◽  
Ph Dependent ◽  
The Stability ◽  
Kinetics Of

Analysis of the pH-dependent stability and millisecond folding kinetics of horse cytochrome c

2015 ◽  
Vol 585 ◽  
pp. 52-63 ◽  
Author(s):  
Rishu Jain ◽  
Rajesh Kumar ◽  
Sandeep Kumar ◽  
Ritika Chhabra ◽  
Mukesh Chand Agarwal ◽  
...  
Keyword(s):  
Cytochrome C ◽  
Folding Kinetics ◽  
Ph Dependent ◽  
Kinetics Of ◽  
Horse Cytochrome

Sequence, Salt, Charge, and the Stability of DNA at High Pressure

1996 ◽  
Author(s):  
Robert B. Macgregor Jr ◽  
John Q. Wu
Keyword(s):  
Molar Volume ◽  
Volume Change ◽  
Salt Concentration ◽  
Electrostatic Interactions ◽  
Proposed Model ◽  
Dna Strands ◽  
Positive Volume ◽  
Ion Radius ◽  
The Stability ◽  
Kinetics Of

The effect of pressure on the helix-coil transition temperature (Tm) is reported for the double-stranded polymers poly(dA)poly(dT), poly[d(A-T)], poly[d(l-C], and poly[d(G-C] and triple-stranded poly(dA)2poly(dT). The Tm increases as a function of pressure, implying a positive volume change for the transition and leading to the conclusion that the molar volume of the coil form is larger than the molar volume of the helix. From the change in Tm as a function of pressure, molar volume changes of the transition (ΔVt) are calculated using the Clapeyron equation and calorimetrically determined enthalpies. For the doublestranded polymers, ΔVt, increases in the order poly[d(l-C] < polyt[d(A-T)] < poly(dA)-poly(dT) < polylcl(G-C)]. The value of ΔVt, for the triple-stranded to single-stranded transition of poly(dA) 2poly(dT) is larger than that of poly[d(G-C)I. The magnitude of ΔVt increases with salt concentration in all cases studied; however, the change of ΔVt with salt concentration depends on the sequence of the DNA and the number of strands involved in the transition. In the model proposed to explain the results, the overall molar volume change of the transition is a function of a negative volume change arising from changes in the electrostatic interactions of the DNA strands, and a positive volume change due to unstacking the bases. The model predicted the direction of the change in the ΔVt for several experiments. The magnitude of AVJ increases with counter ion radius, thus for polyld(A-T)], ΔVt, increases in the series Na+ , K+, Cs+, The ΔVt also increases if the charge on the phosphodiester groups is removed. The kinetics of the formation of double-stranded (dA)19(dT)19 in 50 mM NaCI are slowed approximately 14-fold at 200 MPa relative to atmospheric pressure. The implied volume of activation of +37 ml mol−l in the direction of this change is also in agreement with the proposed model. The stability of double- and triple-stranded DNA helices in water around neutral pH depends on the base composition and sequence, as well as on the ionic strength of the solution. Each of these dependencies also defines how DNA interacts with water.

Effect of Signal Peptide on the Stability and Folding Kinetics of Maltose Binding Protein†

Biochemistry ◽  
2004 ◽  
Vol 43 (12) ◽  
pp. 3608-3619 ◽  
Author(s):  
K. Beena ◽  
Jayant B. Udgaonkar ◽  
R. Varadarajan
Keyword(s):  
Signal Peptide ◽  
Binding Protein ◽  
Maltose Binding Protein ◽  
Folding Kinetics ◽  
The Stability ◽  
Kinetics Of

Membrane curvature affects the stability and folding kinetics of bacteriorhodopsin

2019 ◽  
Vol 76 ◽  
pp. 111-117 ◽  
Author(s):  
Haihong Huang ◽  
Baosheng Ge ◽  
Chenghao Sun ◽  
Shuai Zhang ◽  
Fang Huang
Keyword(s):  
Membrane Curvature ◽  
Folding Kinetics ◽  
The Stability ◽  
Kinetics Of

Effect of Loop Composition on the Stability and Folding Kinetics of RNA Hairpins with Large Loops

Biochemistry ◽  
2015 ◽  
Vol 54 (10) ◽  
pp. 1886-1896 ◽  
Author(s):  
Artem V. Melnykov ◽  
Rajesh K. Nayak ◽  
Kathleen B. Hall ◽  
Alan Van Orden
Keyword(s):  
Folding Kinetics ◽  
Rna Hairpins ◽  
The Stability ◽  
Kinetics Of

Infrared Study of the Stability and Folding Kinetics of a 15-Residueβ-Hairpin

2003 ◽  
Vol 125 (50) ◽  
pp. 15388-15394 ◽  
Author(s):  
Yao Xu ◽  
Rolando Oyola ◽  
Feng Gai
Keyword(s):  
Folding Kinetics ◽  
Infrared Study ◽  
The Stability ◽  
Kinetics Of
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