Fluorescence Evidence That a Phase Transition Causes the Induction Time in the Reduction in Dynamic Tension during Surfactant Adsorption to a Clean Air/Water Interface and a Kinetic–Diffusive Transport Model for the Phase-Induced Induction

2002 ◽  
Vol 253 (2) ◽  
pp. 377-392 ◽  
Author(s):  
Rajeev Subramanyam ◽  
Charles Maldarelli
Keyword(s):  
Phase Transition ◽  
Induction Time ◽  
Transport Model ◽  
Surfactant Adsorption ◽  
Water Interface ◽  
Diffusive Transport ◽  
Dynamic Tension ◽  
Air Water Interface ◽  
Clean Air

From Surface Tension to Molecular Distribution: Modeling Surfactant Adsorption at the Air–Water Interface

Langmuir ◽  
2021 ◽  
Vol 37 (7) ◽  
pp. 2237-2255 ◽  
Author(s):  
Mengsu Peng ◽  
Timothy T. Duignan ◽  
Cuong V. Nguyen ◽  
Anh V. Nguyen
Keyword(s):  
Surface Tension ◽  
Surfactant Adsorption ◽  
Water Interface ◽  
Molecular Distribution ◽  
Distribution Modeling ◽  
Air Water Interface

Temperature dependence of dipalmitoyl phosphatidylcholine monolayer stability

1981 ◽  
Vol 51 (5) ◽  
pp. 1108-1114 ◽  
Author(s):  
J. Goerke ◽  
J. Gonzales
Keyword(s):  
Phase Transition ◽  
Lung Surfactant ◽  
Principal Component ◽  
Water Interface ◽  
Dipalmitoyl Phosphatidylcholine ◽  
Phase Transition Temperatures ◽  
Air Water Interface ◽  
Different Temperatures ◽  
Monolayer Stability ◽  
Isolated Rat

Dipalmitoyl phosphatidylcholine is the principal component of lung surfactant, and knowledge of its behavior as a film spread at the air-water interface is essential for understanding how lung surfactant itself works. We therefore studied the collapse rates of very low surface tension air-water monolayers of dipalmitoyl, dimyristoyl, and palmitoyl-myristoyl phosphatidylcholines at different temperatures. In each case we found that the monolayers abruptly became unstable at temperature 3–4 degree C above their bulk lipid-water phase transition temperatures (Tc). This accords with a comparable increase in Tc occurring in bulk systems subjected to high pressure. These findings are also consistent with the behavior of isolated rat lungs, which have been found to require higher transmural pressures to maintain a given volume on deflation when kept at temperature above the Tc of dipalmitoyl phosphatidylcholine.

Phase transition in adsorbed monolayers of 2-hydroxyethyl laurate at the air-water interface

2000 ◽  
Vol 171 (1-3) ◽  
pp. 105-113 ◽  
Author(s):  
Md.Mufazzal Hossain ◽  
Masaaki Yoshida ◽  
Ken-ichi Iimura ◽  
Noboru Suzuki ◽  
Teiji Kato
Keyword(s):  
Phase Transition ◽  
Water Interface ◽  
Air Water Interface

Phosphocholine reverses inhibition of pulmonary surfactant adsorption caused by C-reactive protein

1995 ◽  
Vol 269 (4) ◽  
pp. L492-L497 ◽  
Author(s):  
T. M. McEachren ◽  
K. M. Keough
Keyword(s):  
Pulmonary Surfactant ◽  
Water Soluble ◽  
Molar Ratio ◽  
Surfactant Adsorption ◽  
Dependent Manner ◽  
Water Interface ◽  
C Reactive Protein ◽  
Molar Ratios ◽  
Reactive Protein ◽  
Air Water Interface

The influence of the acute inflammatory phase protein human C-reactive protein (CRP) on the adsorption of porcine pulmonary surfactant from a subphase into an air-water interface has been investigated. CRP was shown to detract from the ability of surfactant to rapidly adsorb to the air-water interface at a molar ratio of 0.03:1 (protein:phospholipid) (weight ratio, 0.5:1). On a weight basis, CRP was found to be more effective than fibrinogen at reducing the adsorption rate of surfactant. The effect of CRP required the presence of calcium and was reversed by the addition of phosphocholine in a concentration-dependent manner. The inhibition of surfactant adsorption by CRP was effectively eliminated by the addition of phosphocholine at a molar ratio of 300:1 (phosphocholine:CRP), but it was not diminished by the addition of identical molar ratios of o-phosphoethanolamine or DL-alpha-glycerophosphate at the same molar ratios. These data suggest that the potent inhibition of surfactant adsorption by CRP is primarily a result of a specific interaction between CRP and the phosphocholine headgroup of surfactant lipids in the subphase and that it can be reversed by the water-soluble CRP ligand, phosphocholine.

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