Identification and Characterization of cDNAs Encoding Four Novel Proteins that Interact with Translin Associated Factor-X

Genomics ◽  
2002 ◽  
Vol 79 (6) ◽  
pp. 799-808 ◽  
Author(s):  
Jeffrey D. Bray ◽  
Vargheese M. Chennathukuzhi ◽  
Norman B. Hecht
Keyword(s):  
Factor X ◽  
Associated Factor ◽  
Novel Proteins ◽  
Identification And Characterization

scholarly journals Identification and Characterization of Two Novel Proteins Affecting Fission Yeast γ-tubulin Complex Function

2004 ◽  
Vol 15 (5) ◽  
pp. 2287-2301 ◽  
Author(s):  
Srinivas Venkatram ◽  
Joseph J. Tasto ◽  
Anna Feoktistova ◽  
Jennifer L. Jennings ◽  
Andrew J. Link ◽  
...  
Keyword(s):  
Fission Yeast ◽  
Complex Function ◽  
Novel Proteins ◽  
Astral Microtubule ◽  
Different Types ◽  
Associated Proteins ◽  
Microtubule Formation ◽  
Identification And Characterization ◽  
Microtubule Function

The γ-tubulin complex, via its ability to organize microtubules, is critical for accurate chromosome segregation and cytokinesis in the fission yeast, Schizosaccharomyces pombe. To better understand its roles, we have purified the S. pombe γ-tubulin complex. Mass spectrometric analyses of the purified complex revealed known components and identified two novel proteins (i.e., Mbo1p and Gfh1p) with homology to γ-tubulin–associated proteins from other organisms. We show that both Mbo1p and Gfh1p localize to microtubule organizing centers. Although cells deleted for either mbo1+ or gfh1+ are viable, they exhibit a number of defects associated with altered microtubule function such as defects in cell polarity, nuclear positioning, spindle orientation, and cleavage site specification. In addition, mbo1Δ and gfh1Δ cells exhibit defects in astral microtubule formation and anchoring, suggesting that these proteins have specific roles in astral microtubule function. This study expands the known roles of γ-tubulin complex components in organizing different types of microtubule structures in S. pombe.

Identification and characterization of a TNF receptor-associated factor in Dugesia japonica

Gene ◽  
2019 ◽  
Vol 681 ◽  
pp. 52-61 ◽  
Author(s):  
Wenjing Hu ◽  
Weiwei Wu ◽  
Shimin Sun ◽  
Zuojun Liu ◽  
Ao Li ◽  
...  
Keyword(s):  
Tnf Receptor ◽  
Associated Factor ◽  
Dugesia Japonica ◽  
Identification And Characterization

Identification and Characterization of Human Fas Associated Factor 1, hFAF1

1999 ◽  
Vol 262 (2) ◽  
pp. 388-394 ◽  
Author(s):  
Seung-Wook Ryu ◽  
Suhn-Kee Chae ◽  
Kong-Joo Lee ◽  
Eunhee Kim
Keyword(s):  
Associated Factor ◽  
Identification And Characterization

scholarly journals Identification and characterization of novel proteins associated with CHD4

2021 ◽  
Author(s):  
Chihiro Sakaguchi ◽  
Kazuya Ichihara ◽  
Akihiro Nita ◽  
Yuta Katayama ◽  
Keiichi I. Nakayama
Keyword(s):  
Novel Proteins ◽  
Identification And Characterization

scholarly journals Identification and Characterization of Vascular Calcification–Associated Factor, a Novel Gene Upregulated During Vascular Calcification In Vitro and In Vivo

2005 ◽  
Vol 25 (9) ◽  
pp. 1851-1857 ◽  
Author(s):  
M. Yvonne Alexander ◽  
Fiona L. Wilkinson ◽  
John Paul Kirton ◽  
Claire Farrington Rock ◽  
Georgina D.M. Collett ◽  
...  
Keyword(s):  
Vascular Calcification ◽  
Associated Factor ◽  
Novel Gene ◽  
Identification And Characterization
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