Characterization of [3H]CGP 12177 Binding to β-Adrenergic Receptors in Intact Eel Hepatocytes

2001 ◽  
Vol 121 (3) ◽  
pp. 223-231 ◽  
Author(s):  
Elena Fabbri ◽  
Corrado Selva ◽  
Thomas W. Moon ◽  
Antonio Capuzzo
1983 ◽  
Vol 96 (1-2) ◽  
pp. 101-104 ◽  
Author(s):  
István Laszlovsky ◽  
Sándor L. Erdö

2015 ◽  
Vol 204 (3) ◽  
pp. 363-365 ◽  
Author(s):  
Sandra Hoffmann ◽  
Torsten Müller ◽  
Getu Abraham

2017 ◽  
Vol 42 (3) ◽  
pp. 278-284 ◽  
Author(s):  
Gina M. Many ◽  
Zachary Kendrick ◽  
Chelsea L. Deschamps ◽  
Courtney Sprouse ◽  
Laura L. Tosi ◽  
...  

Studies of physical activity behaviours have increasingly shown the importance of heritable factors such as genetic variation. Nonsynonymous polymorphisms of alpha-actinin 3 (ACTN3) and the β-adrenergic receptors 1 and 3 (ADRB1 and ADRB3) have been previously associated with exercise capacity and cardiometabolic health. We thus hypothesized that these polymorphisms are also related to physical activity behaviours in young adults. To test this hypothesis we examined relationships between ACTN3 (R577X), ARDB1 (Arg389Gly), ADRB3 (Trp64Arg), and physical activity behaviours in university students. We stratified for student enrollment in kinesiology degree programs compared with nonmajors as we previously found this to be a predictor of physical activity. We did not identify novel associations between physical activity and ACTN3. However, the minor alleles of ADRB1 and ADRB3 were significantly underrepresented in kinesiology students compared with nonmajors. Furthermore, carriers of the ADRB1 minor allele reported reduced participation in moderate physical activity and increased afternoon fatigue compared with ancestral allele homozygotes. Together, these findings suggest that the heritability of physical activity behaviours in young adults may be linked to nonsynonymous polymorphisms within β-adrenergic receptors.


Life Sciences ◽  
1996 ◽  
Vol 60 (4-5) ◽  
pp. 315-324 ◽  
Author(s):  
Didier Morin ◽  
Rosa Sapena ◽  
Roland Zini ◽  
Brigitte Onteniente ◽  
Jean-Paul Tillement

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