Dermacentor andersoni: Salivary Gland Proteins Suppressing T-Lymphocyte Responses to Concanavalin A in Vitro

1995 ◽  
Vol 81 (3) ◽  
pp. 262-271 ◽  
Author(s):  
D.K. Bergman ◽  
R.N. Ramachandra ◽  
S.K. Wikel
Keyword(s):  
Salivary Gland ◽  
T Lymphocyte ◽  
Concanavalin A ◽  
Dermacentor Andersoni ◽  
Lymphocyte Responses

scholarly journals Sendai virus-specific, H-2-restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands.

1980 ◽  
Vol 152 (6) ◽  
pp. 1805-1810 ◽  
Author(s):  
J P Lake ◽  
M E Andrew ◽  
C W Pierce ◽  
T J Braciale
Keyword(s):  
T Lymphocyte ◽  
Nude Mice ◽  
Sendai Virus ◽  
Cytotoxic T Lymphocyte ◽  
Target Cells ◽  
Self Recognition ◽  
Parental Haplotype ◽  
Lymphocyte Responses ◽  
Ctl Responses

The in vitro secondary cytotoxic T lymphocyte (CTL) response to Sendai virus-treated stimulator cells by primed spleen cells from thymus gland-grafted nude mice was examined. BALB/c (H-2d) nude mice grafted with allogeneic C57BL/10 (H-2b) thymus glands developed CTL responses directed exclusively to Sendai virus-infected H-2d target cells. (C57BL/6 X BALB/c)F1 nude mice grafted with thymus glands of either parent developed CTL responses preferentially against infected target cells expressing the MHC antigens present in the parental thymus graft, but also had detectable activity for infected target cells of the parental haplotype not expressed in the thymus. These results provide evidence against the concept that self recognition by MHC-restricted CTL is directed exclusively by the MCH type of the thymus.

In vitro effects of malathion and O,O,S-trimethyl phosphorothioate on cytotoxic T-lymphocyte responses

1985 ◽  
Vol 24 (2) ◽  
pp. 260-266 ◽  
Author(s):  
Kathleen E. Rodgers ◽  
Marcia H. Grayson ◽  
Toshiko Imamura ◽  
Bruce H. Devens
Keyword(s):  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
In Vitro Effects ◽  
Lymphocyte Responses

Glucuronoxylomannan of Cryptococcus neoformans exacerbates in vitro yeast cell growth by interleukin 10-dependent inhibition of CD4+ T lymphocyte responses

2003 ◽  
Vol 222 (2) ◽  
pp. 116-125 ◽  
Author(s):  
Regis Mariano Andrade ◽  
Geisy Monteiro Almeida ◽  
George Alexandre DosReis ◽  
Cleonice Alves Melo Bento
Keyword(s):  
Cell Growth ◽  
Yeast Cell ◽  
Cryptococcus Neoformans ◽  
T Lymphocyte ◽  
Interleukin 10 ◽  
Dependent Inhibition ◽  
Lymphocyte Responses

Characterization of a factor(s) which synergizes with recombinant interleukin 2 in promoting allogeneic human cytolytic T-lymphocyte responses in vitro

1988 ◽  
Vol 111 (1) ◽  
pp. 39-54 ◽  
Author(s):  
Henry L. Wong ◽  
Darien E. Wilson ◽  
James C. Jenson ◽  
Philip C. Familletti ◽  
Donna L. Stremlo ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Interleukin 2 ◽  
Cytolytic T Lymphocyte ◽  
Recombinant Interleukin 2 ◽  
Lymphocyte Responses

Ion and Water Balance in the Ixodid Tick Dermacentor Andersoni

1973 ◽  
Vol 58 (2) ◽  
pp. 549-564
Author(s):  
W. R. KAUFMAN ◽  
J. E. PHILLIPS
Keyword(s):  
Salivary Gland ◽  
Fluid Secretion ◽  
Ixodid Tick ◽  
Artificial Medium ◽  
Salivary Duct ◽  
Bathing Medium ◽  
Dermacentor Andersoni ◽  
Cl Secretion ◽  
Wide Range

1. The salivary gland of the ixodid tick, Dermacentor andersoni, can be induced to secrete fluid for at least 6 h when bathed in an artificial medium in vitro. 2. Fluid secretion appears to be a consequence of active Cl secretion since (a) it is inhibited by 95% when nitrate and by 100% when acetate replaces Cl in the bathing medium; however, bromide can support secretion as well as Cl, (b) the rates of fluid and Cl secretion are linearly related to the concentration of Cl in the medium; and (c) the S/H ratio for Cl is greater than unity at all concentrations despite a transacinar P.D. of 35 mV (lumen negative). 3. Although (in the presence of Na) a low concentration of K in the bathing medium stimulates the rate of fluid secretion fivefold, higher concentrations of K inhibit fluid secretion. The latter is largely due to a direct effect of K ion and not simply to increased osmotic pressure or reduced Na concentration. Fluid secretion is completely in hibited by 10-6 M ouabain. On the basis of these observations we propose that fluid secretion may be dependent on a Na-K activated ‘pump ATPase’, which is somehow involved in cation secretion. The S/H ratios of Na and K are greater than unity at all medium concentrations. 4. The saliva secreted in vitro is slightly hypo-osmotic to the bathing medium over a wide range of medium concentration (300-920 mOsm/l). We postulate that the primary saliva is iso- or hyper-osmotic to the bathing medium; the final elaborated saliva is probably rendered hypo-osmotic by a process of solute reabsorption somewhere between the acini and the orifice of the main salivary duct.

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