Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro

2001 ◽  
Vol 267 (1) ◽  
pp. 107-114 ◽  
Author(s):  
R. Tatsumi ◽  
S.M. Sheehan ◽  
H. Iwasaki ◽  
A. Hattori ◽  
R.E. Allen
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
Mechanical Stretch ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells

scholarly journals miR-194-5p negatively regulates the proliferation and differentiation of rabbit skeletal muscle satellite cells

2020 ◽  
Author(s):  
Yu Shi ◽  
Xudong Mao ◽  
Mingcheng Cai ◽  
Shenqiang Hu ◽  
Xiulan Lai ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
Mammalian Species ◽  
Muscle Growth ◽  
Luciferase Reporter ◽  
Stem Cell Population ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells ◽  
Proliferation And Differentiation

Abstract Skeletal muscle satellite cells (SMSCs), also known as a multipotential stem cell population, play a crucial role during muscle growth and regeneration. In recent years, numerous miRNAs have been associated with the proliferation and differentiation of SMSCs in a number of mammalian species; however, the regulatory mechanisms of miR-194-5p in rabbit SMSCs still remain scarce. In this study, miR-194-5p was first observed to be highly expressed in the rabbit leg muscle. Furthermore, both the mimics and inhibitor of miR-194-5p were used to explore its role in the proliferation and differentiation of rabbit SMSCs cultured in vitro. Results from both EdU and CCK8 assays showed that miR-194-5p inhibited the proliferation of SMSCs. Meanwhile, Mef2c was identified as a target gene of miR-194-5p based on the dual-luciferase reporter assay results. In addition, upregulation of miR-194-5p decreased the expression levels of Mef2c and MyoG during rabbit SMSCs differentiation on Days 3 and 7 of in vitro culture. Taken together, these data demonstrated that miR-194-5p negatively regulates the proliferation and differentiation of rabbit SMSCs by targeting Mef2c.

scholarly journals HDAC4 Regulates the Proliferation, Differentiation and Apoptosis of Chicken Skeletal Muscle Satellite Cells

Animals ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 84 ◽  
Author(s):  
Jing Zhao ◽  
Xiaoxu Shen ◽  
Xinao Cao ◽  
Haorong He ◽  
Shunshun Han ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
Muscle Development ◽  
Critical Role ◽  
Muscle Growth ◽  
Positive Role ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells ◽  
Chicken Skeletal Muscle

The development of skeletal muscle satellite cells (SMSCs) is a complex process that could be regulated by many genes. Previous studies have shown that Histone Deacetylase 4 (HDAC4) plays a critical role in cell proliferation, differentiation, and apoptosis in mouse. However, the function of HDAC4 in chicken muscle development is still unknown. Given that chicken is a very important meat-producing animal that is also an ideal model to study skeletal muscle development, we explored the functions of HDAC4 in chicken SMSCs after the interference of HDAC4. The results showed that HDAC4 was enriched in embryonic skeletal muscle, and it was highly expressed in embryonic muscle than in postnatal muscles. Meanwhile, knockdown of HDAC4 could significantly inhibit the proliferation and differentiation of chicken SMSCs but had no effect on the apoptosis of SMSCs as observed in a series of experiment conducted in vitro. These results indicated that HDAC4 might play a positive role in chicken skeletal muscle growth and development.

In vitro culture and induced differentiation of sheep skeletal muscle satellite cells

2012 ◽  
Vol 36 (6) ◽  
pp. 579-587 ◽  
Author(s):  
Haiqing Wu ◽  
Yu Ren ◽  
Shuo Li ◽  
Wei Wang ◽  
Jianlong Yuan ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
In Vitro Culture ◽  
Satellite Cells ◽  
Induced Differentiation ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells

scholarly journals Altered in vitro Proliferation of Mouse SOD1-G93A Skeletal Muscle Satellite Cells

2012 ◽  
Vol 11 (3) ◽  
pp. 153-164 ◽  
Author(s):  
Raquel Manzano ◽  
Janne M. Toivonen ◽  
Ana C. Calvo ◽  
Sara Oliván ◽  
Pilar Zaragoza ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
In Vitro Proliferation ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells

Preliminary experiments on mechanical stretch-induced activation of skeletal muscle satellite cells in vivo

2006 ◽  
Vol 77 (5) ◽  
pp. 518-525 ◽  
Author(s):  
Tomowa SAKATA ◽  
Ryuichi TATSUMI ◽  
Michiko YAMADA ◽  
Sei-Ichi SHIRATSUCHI ◽  
Shinpei OKAMOTO ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
Mechanical Stretch ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells

Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro

1995 ◽  
Vol 165 (2) ◽  
pp. 307-312 ◽  
Author(s):  
Ronald E. Allen ◽  
Shannon M. Sheehan ◽  
Richard G. Taylor ◽  
Teresa L. Kendall ◽  
Glenna M. Rice
Keyword(s):  
Skeletal Muscle ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Satellite Cells ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells ◽  
Hepatocyte Growth

Low-pH preparation of skeletal muscle satellite cells can be used to study activation in vitro

2006 ◽  
Vol 38 (10) ◽  
pp. 1678-1685 ◽  
Author(s):  
Ryuichi Tatsumi ◽  
Michiko Yamada ◽  
Yoshitaka Katsuki ◽  
Shinpei Okamoto ◽  
Junji Ishizaki ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Satellite Cells ◽  
Low Ph ◽  
Muscle Satellite Cells ◽  
Skeletal Muscle Satellite Cells
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