scholarly journals The Role of Interleukin-4 in the Regulation of Mouse Primordial Germ Cell Numbers

1996 ◽  
Vol 174 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Julie E. Cooke ◽  
Janet Heasman ◽  
Chris C. Wylie
Keyword(s):  
Germ Cell ◽  
Primordial Germ Cell ◽  
Interleukin 4 ◽  
Cell Numbers ◽  
Mouse Primordial Germ Cell

scholarly journals Role of Fibroblast Growth Factors and Their Receptors in Mouse Primordial Germ Cell Growth1

1998 ◽  
Vol 59 (5) ◽  
pp. 1224-1229 ◽  
Author(s):  
James L. Resnick ◽  
Mariastela Ortiz ◽  
Jonathan R. Keller ◽  
Peter J. Donovan
Keyword(s):  
Growth Factors ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Fibroblast Growth Factors ◽  
Fibroblast Growth ◽  
Mouse Primordial Germ Cell

scholarly journals The proliferation role of LH on porcine primordial germ cell‐like cells (pPGCLCs) through ceRNA network construction

2021 ◽  
Vol 11 (10) ◽  
Author(s):  
Ming‐Yu Zhang ◽  
Yu Tian ◽  
Shu‐Er Zhang ◽  
Hong‐Chen Yan ◽  
Wei Ge ◽  
...  
Keyword(s):  
Germ Cell ◽  
Primordial Germ Cell ◽  
Network Construction ◽  
Cerna Network

scholarly journals MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis

PLoS ONE ◽  
2008 ◽  
Vol 3 (3) ◽  
pp. e1738 ◽  
Author(s):  
Katsuhiko Hayashi ◽  
Susana M. Chuva de Sousa Lopes ◽  
Masahiro Kaneda ◽  
Fuchou Tang ◽  
Petra Hajkova ◽  
...  
Keyword(s):  
Germ Cell ◽  
Primordial Germ Cell ◽  
Cell Development ◽  
Microrna Biogenesis ◽  
Germ Cell Development ◽  
Mouse Primordial Germ Cell

scholarly journals Evidence for a role of matrix metalloproteinases and their inhibitors in primordial germ cell migration

Andrology ◽  
2013 ◽  
Vol 1 (5) ◽  
pp. 779-786 ◽  
Author(s):  
A. Díez-Torre ◽  
M. Díaz-Núñez ◽  
C. Eguizábal ◽  
U. Silván ◽  
J. Aréchaga
Keyword(s):  
Cell Migration ◽  
Matrix Metalloproteinases ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

scholarly journals BAX regulates follicular endowment in mice

Reproduction ◽  
2007 ◽  
Vol 133 (5) ◽  
pp. 865-876 ◽  
Author(s):  
Chuck R Greenfeld ◽  
Melissa E Pepling ◽  
Janice K Babus ◽  
Priscilla A Furth ◽  
Jodi A Flaws
Keyword(s):  
Cell Viability ◽  
Germ Cell ◽  
Proliferative Activity ◽  
Primordial Germ Cell ◽  
Initial Endowment ◽  
Regulatory Activity ◽  
Wild Type ◽  
X Protein ◽  
Primordial Follicles

It is believed that the endowment of primordial follicles in mammalian ovaries is finite. Once follicles are depleted, infertility ensues. Thus, the size of the initial endowment has consequences for fertility and reproductive longevity. Follicular endowment is comprised of various processes that culminate with the incorporation of meiosis-arrested oocytes into primordial follicles. Apoptosis is prominent during follicular endowment, and apoptosis regulatory genes are involved in its regulation. Conflicting data exist with regard to the role of the proapoptotic Bcl-2 associated X protein (BAX) in follicular endowment. Therefore, we investigated the role of BAX during follicular endowment in embryonic and neonatal ovaries. We found that BAX is involved in regulating follicular endowment in mice. Deletion ofBaxyields increased oocyte numbers in embryonic ovaries and increased follicle numbers in neonatal ovaries when compared with wild-type ovaries. Increased follicular endowment inBax−/−ovaries is not due to enhanced germ cell viability. Further, it is not due to an increased primordial germ cell (PGC) allotment, a delay in the onset of meiosis, or altered proliferative activity of oogonia. Instead, our data suggest that the regulatory activity of BAX in follicular endowment likely occurs during PGC migration, prior to PGC colonization of the gonad.

scholarly journals The role of cadherins during primordial germ cell migration and early gonad formation in the mouse

2000 ◽  
Vol 91 (1-2) ◽  
pp. 143-152 ◽  
Author(s):  
Michael R Bendel-Stenzel ◽  
Miranda Gomperts ◽  
Robert Anderson ◽  
Janet Heasman ◽  
Christopher Wylie
Keyword(s):  
Cell Migration ◽  
Germ Cell ◽  
Primordial Germ Cell ◽  
Germ Cell Migration

scholarly journals Hematopoietic activity in putative mouse primordial germ cell populations

2015 ◽  
Vol 136 ◽  
pp. 53-63 ◽  
Author(s):  
Maria Lucia Scaldaferri ◽  
Francesca Gioia Klinger ◽  
Donatella Farini ◽  
Anna Di Carlo ◽  
Rita Carsetti ◽  
...  
Keyword(s):  
Germ Cell ◽  
Primordial Germ Cell ◽  
Cell Populations ◽  
Mouse Primordial Germ Cell ◽  
Hematopoietic Activity

scholarly journals The crucial role of Activin A on the formation of primordial germ cell-like cells from skin-derived stem cells in vitro

Cell Cycle ◽  
2015 ◽  
Vol 14 (19) ◽  
pp. 3016-3029 ◽  
Author(s):  
Rui Sun ◽  
Yuan-Chao Sun ◽  
Wei Ge ◽  
Hui Tan ◽  
Shun-Feng Cheng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Germ Cell ◽  
Crucial Role ◽  
Primordial Germ Cell ◽  
Activin A
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