scholarly journals Anteriorization of CRABP-I Expression by Retinoic Acid in the Developing Mouse Central Nervous System and Its Relationship to Teratogenesis

1995 ◽  
Vol 168 (2) ◽  
pp. 514-528 ◽  
Author(s):  
L. Leonard ◽  
C. Horton ◽  
M. Maden ◽  
J.A. Pizzey
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Retinoic Acid ◽  
Crabp I ◽  
Mouse Central Nervous System

scholarly journals CB1 and LPA1 Receptors Relationship in the Mouse Central Nervous System

2019 ◽  
Vol 12 ◽  
Author(s):  
Estíbaliz González de San Román ◽  
Iván Manuel ◽  
Catherine Ledent ◽  
Jerold Chun ◽  
Fernando Rodríguez de Fonseca ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mouse Central Nervous System

scholarly journals Apoptotic Cells, Including Macrophages, Are Prominent in Theiler's Virus-Induced Inflammatory, Demyelinating Lesions

2003 ◽  
Vol 77 (7) ◽  
pp. 4383-4388 ◽  
Author(s):  
Brian P. Schlitt ◽  
Matthew Felrice ◽  
Mary Lou Jelachich ◽  
Howard L. Lipton
Keyword(s):  
Central Nervous System ◽  
T Cells ◽  
Nervous System ◽  
In Situ Hybridization ◽  
Apoptotic Cells ◽  
Theiler's Virus ◽  
Demyelinating Lesions ◽  
Encephalomyelitis Virus ◽  
Mouse Central Nervous System

ABSTRACT Theiler's murine encephalomyelitis virus (TMEV) persists in the mouse central nervous system principally in macrophages, and infected macrophages in culture undergo apoptosis. We have detected abundant apoptotic cells in perivascular cuffs and inflammatory, demyelinating lesions of SJL mice chronically infected with TMEV. T cells comprised 74% of apoptotic cells, while 8% were macrophages, 0.6% were astrocytes, and ∼17% remained unidentified. In situ hybridization revealed viral RNA in ∼1% of apoptotic cells.

Induction of a RAR beta 2-lacZ transgene by retinoic acid reflects the neuromeric organization of the central nervous system

Development ◽  
1992 ◽  
Vol 116 (4) ◽  
pp. 977-983 ◽  
Author(s):  
A. Zimmer ◽  
A. Zimmer
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Retinoic Acid ◽  
Retinoic Acid Receptor ◽  
Induction Pattern ◽  
The Central Nervous System ◽  
Beta 2 ◽  
Transgenic Embryos ◽  
Craniofacial Defects ◽  
Pair Rule

The hormone retinoic acid (RA) has been implicated in the organization of the anteroposterior (AP) body axis. In this paper, we describe the effects of RA on the activity of the RA-inducible retinoic acid receptor-beta 2 (RAR beta 2) promoter. When transgenic embryos carrying a RAR beta 2-lacZ reporter gene were exposed to a single dose of RA between gestational days 8.5 to 10.5, lacZ expression was induced in the anterior central nervous system (CNS). Strikingly, the transgene was expressed in a segmented pattern reminiscent of that of Drosophila ‘pair-rule’ genes. RA treatment of midgastrulation embryos at day 7.5 disturbed the segmentation and produced severe craniofacial defects. We discuss the possibility that the entire anterior CNS is segmented and that this segmentation is reflected by the RAR beta 2-lacZ induction pattern.

scholarly journals Targeted DNA transfection into the mouse central nervous system using laser-induced stress waves

2005 ◽  
Vol 10 (6) ◽  
pp. 060501 ◽  
Author(s):  
Yasushi Satoh ◽  
Yasunari Kanda ◽  
Mitsuhiro Terakawa ◽  
Minoru Obara ◽  
Katsushige Mizuno ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Stress Waves ◽  
Dna Transfection ◽  
Induced Stress ◽  
Mouse Central Nervous System

scholarly journals Elevated expression of membrane type 1 metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system

FEBS Letters ◽  
2000 ◽  
Vol 481 (3) ◽  
pp. 227-234 ◽  
Author(s):  
Silvia Rathke-Hartlieb ◽  
Petra Budde ◽  
Stefan Ewert ◽  
Uwe Schlomann ◽  
Martin Sebastian Staege ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Reactive Astrocytes ◽  
Elevated Expression ◽  
Membrane Type ◽  
Mouse Central Nervous System

scholarly journals Floor plate descendants in the ependyma of the adult mouse Central Nervous System

2017 ◽  
Vol 61 (3-4-5) ◽  
pp. 257-265 ◽  
Author(s):  
Sophie Khazanov ◽  
Yael Paz ◽  
Amit Hefetz ◽  
Ben J. Gonzales ◽  
Yaara Netser ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Adult Mouse ◽  
Floor Plate ◽  
Mouse Central Nervous System
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