Alterations in Nitric Oxide Synthase Activity and Expression in Submandibular Glands of NOD Mice

2001 ◽  
Vol 101 (1) ◽  
pp. 86-93 ◽  
Author(s):  
Florencia Rosignoli ◽  
Nora B. Goren ◽  
Claudia Pérez Leirós
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Nod Mice ◽  
Submandibular Glands ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

Effect of KH-305 on the Nitric Oxide Synthase Activity and Erectile Dysfunction in Young Rats

2007 ◽  
Vol 36 (3) ◽  
pp. 305-310 ◽  
Author(s):  
Eun-Jeong Lee ◽  
Hee-Seok Kim ◽  
Byoung-Chul Kim ◽  
Sung-Wan Hwang ◽  
Sung-Yeoun Hwang
Keyword(s):  
Nitric Oxide ◽  
Erectile Dysfunction ◽  
Nitric Oxide Synthase ◽  
Young Rats ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

Inhibition of Nitric Oxide Synthase Activity by Zn2+ Ion

Biochemistry ◽  
1995 ◽  
Vol 34 (46) ◽  
pp. 15091-15095 ◽  
Author(s):  
Anthony Persechini ◽  
Kirk McMillan ◽  
Bettie Sue Siler Masters
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

scholarly journals Reduced nitric oxide synthase and cyclo-oxygenase activity in the uterus of non-obese diabetic mice

Reproduction ◽  
2006 ◽  
Vol 132 (6) ◽  
pp. 931-938 ◽  
Author(s):  
Valeria Roca ◽  
Luciana Larocca ◽  
Mario Calafat ◽  
Julieta Aisemberg ◽  
Roberto Meiss ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Nod Mice ◽  
Cytokine Response ◽  
Autoimmune Response ◽  
Smooth Muscle Relaxation ◽  
Suitable Model ◽  
Functional Interaction ◽  
Th1 Cytokine ◽  
Oxide Synthase

A functional interaction between progesterone, Th2 cytokines and a suitable balance between nitric oxide and prostaglandins in the uterus is considered to have a major role in the success of embryo implantation and pregnancy. Non-obese diabetic (NOD) mice offer a suitable model to study the modulatory role of Th1 cytokines on uterus signalling and function, since at the prediabetic stage they develop a spontaneous Th1 autoimmune response against exocrine glands similar to Sjögren’s syndrome. Vasoactive intestinal peptide (VIP) is a vasoactive neuro- and immunopeptide that promotes Th2 profiles and contributes to the smooth muscle relaxation and vasodilation. The aim of the present study was to investigate the activities of nitric oxide synthase and cyclo-oxygenase and the effect of VIP in the uterus of NOD mice with an emerging Th1 cytokine response. We present evidence of a reduced basal and VIP-stimulated activity of both enzymes in the uterus of NOD mice compared with normal BALB/c mice in proestrus. An altered functional interaction between both enzymes is also present in NOD mice at the time when increased levels of serum interleukin (IL)-12 and tumour necrosis factor-α but not interferon (IFN)-γ or IL-10 were detected. We conclude that signalling alterations in uteri of NOD mice are simultaneous to the onset of a systemic Th1 cytokine response.

scholarly journals Time Course of Inducible Nitric Oxide Synthase Activity Following Endotoxin Administration in Dogs

Nitric Oxide ◽  
2001 ◽  
Vol 5 (2) ◽  
pp. 208-211 ◽  
Author(s):  
Jean-Charles Preiser ◽  
Haibo Zhang ◽  
Bernard Vray ◽  
Andreas Hrabak ◽  
Jean-Louis Vincent
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Time Course ◽  
Endotoxin Administration ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity ◽  
Inducible Nitric Oxide

Neuroprotective Effect of Chuk-Me-Sun-Dan on NMDA- and AMPA-Evoked Nitric Oxide Synthase Activity in Mouse Brain

2005 ◽  
Vol 27 (3) ◽  
pp. 499-514 ◽  
Author(s):  
Byung-Soo Koo ◽  
Eun-Gyu Choi ◽  
Jae-Bok Park ◽  
Chang-Ho Cho ◽  
Kang-Hyun Chung ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Mouse Brain ◽  
Neuroprotective Effect ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity

scholarly journals Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia

2014 ◽  
Vol 11 (1) ◽  
Author(s):  
Massimo Lazzaro ◽  
Barbara Bettegazzi ◽  
Marco Barbariga ◽  
Franca Codazzi ◽  
Daniele Zacchetti ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Cytokine Secretion ◽  
Activated Microglia ◽  
Oxide Synthase ◽  
Nitric Oxide Synthase Activity
Sign in / Sign up

Export Citation Format

Share Document