RESTING CYST WALL GLYCOPROTEINS ISOLATED FROM TWO COLPODID CILIATES ARE GLYCINE-RICH PROTEINS

Leiomyoma is a benign mesenchymal tumor that develops from smooth muscle cells. It can present in various histological variants. Leiomyoma with bizarre nuclei is an infrequent variant of uterine smooth muscle neoplasm. It is characterized by focally or diffusely distributed bizarre cells on the background of a typical leiomyoma. These bizarre cells are large, multinucleated, or multilobulated and have an eosinophilic cytoplasm. Even though leiomyomas with bizarre nuclei display benign clinical behavior, their differential diagnosis from leiomyosarcoma can sometimes be difficult. Leiomyoma has been described most commonly in the uterus. There is no case of leiomyoma originating from paratubal cysts described in the literature. In this article, we present a rare case of leiomyoma with bizarre nuclei originating from a paratubal cyst.

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Mesenteric Cysts: A Retrospective Review. Its Not All That Simple

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqaa161.257 ◽

2020 ◽

Vol 154 (Supplement_1) ◽

pp. S117-S118

Author(s):

M Bourgeau ◽

V Avadhani

Keyword(s):

Cyst Wall ◽

Imaging Techniques ◽

Case Reports ◽

Lymphatic Vessels ◽

Mucinous Cystadenoma ◽

Final Diagnosis ◽

Cystic Mass ◽

Pathological Examination ◽

Urachal Cyst ◽

Mesenteric Cysts

Abstract Introduction/Objective Mesenteric cysts are rare intra-abdominal lesions in adults. However, with the advanced imaging techniques and laparoscopic techniques, they are more often being identified and resected when clinically significant. There is a lack of detailed information in histopathology (except as case reports) since mesentery is generally neglected in our organ-based textbooks. The aim of our study is to highlight the importance of identifying and classifying mesenteric cystic lesions; they are not all that simple. Methods We performed a retrospective search on all mesenteric cysts submitted as excisions in our electronic database from 2013-2019. We classified them as per the de Perrot (PMID: 11053936) classification with modification. Results Our search showed: A. Lymphatic origin-11 (lymphangioma-10, Lymphangioma hamartomatous-1, associated with LAM-0), B. Mesothelial origin-68 (Benign mesothelial cysts-57, multilocular mesothelial cyst-11), C. Enteric origin- 3, D. Urogenital origin (Urachal cyst, mullerian inclusion cyst)-9, E. Mature cystic teratom-2, F. Pseudocyst-12, G. Epithelial cyst (not urogenital)- 11 (a/w LAMN-3, MCN-4, Mucinous cystadenoma-4), H. Associated with carcinoma-2. Case illustration: A 61-year-old male presented with worsening dysphagia, emesis and hiccups. A CT scan showed a 21.2 cm cystic mass with at least one septation (Fig 1). The cyst was resected. On gross pathological examination, the cyst measured 18 cm in greatest dimension with a thick, rough, tan-brown capsule. Microscopic examination showed a fibrous capsule, and cyst wall composed of numerous lymphatic vessels (CD31 positive) and prominent smooth muscle proliferation (Desmin positive). Scattered lymphoid aggregates were also present throughout the cyst wall. No definite epithelial lining was identified and was suspected to have been denuded. HMB-45 immunostain was negative, ruling out association with LAM. The final diagnosis of a Lymphangiomyoma, hamartomatous was rendered. Conclusion Though most of the mesenteric cysts are benign, some of them are significantly important such as Lymphangiomyoma (esp secondary to LAM), MCN, those associated with LAMN etc. and identifying and differentiating from their mimics has distinct clinical implications.

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Cystic Encapsulated Papillary Carcinoma in the Male Breast: An Unusual Feature With a Diagnostic Challenge

International Journal of Surgical Pathology ◽

10.1177/10668969211018754 ◽

2021 ◽

pp. 106689692110187

Author(s):

Rongying Li ◽

Karan Saluja ◽

Brenda Mai ◽

Michael Covinsky ◽

Hongxia Sun

Keyword(s):

Papillary Carcinoma ◽

Cyst Wall ◽

Correct Diagnosis ◽

Nipple Discharge ◽

Left Breast ◽

Male Breast ◽

Unusual Feature ◽

Breast Mass ◽

Repeat Biopsy ◽

Bloody Nipple Discharge

Papillary carcinoma in the male breast is uncommon. Here, we report a case of a large encapsulated papillary carcinoma (EPC) in a 62-year-old male. The patient presented with a left breast mass of 1-year duration and bloody nipple discharge for several days. Mammography and breast ultrasonography showed a large left breast mass. The initial biopsy demonstrated fat necrosis with acute and chronic inflammation only. Due to clinical suspicion, a repeat biopsy was performed and revealed scant fragments of papillary carcinoma in a background of inflammation. The patient underwent left total mastectomy. Grossly, the breast contained a 9.0 cm entirely cystic lesion lined by a hemorrhagic thick fibrotic wall. No solid area was identified in the cyst. The entire cyst wall was examined under microscopy; only a few sections with papillary carcinoma were identified. The lesion was confined to the cyst wall; so, a diagnosis of EPC was made. Compared to the previously reported EPC cases of male breast, the lesion of this case was unusually cystic, which making the diagnosis challenging. Therefore, awareness of this unusual feature, repeat biopsy when the pathology result is discordant, and extensive sampling of the lesion are essential for making the correct diagnosis and guiding patient management.

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A novel ARID/Bright-like protein involved in transcriptional activation of cyst wall protein 1 gene in Giardia lamblia. VOLUME 282 (2007) PAGES 8905-8914

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)87469-9 ◽

2007 ◽

Vol 282 (21) ◽

pp. 15940

Author(s):

Chih-Hung Wang ◽

Li-Hsin Su ◽

Chin-Hung Sun

Keyword(s):

Cyst Wall ◽

Transcriptional Activation ◽

Giardia Lamblia

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Utility of endoscopic transpapillary pancreatic cyst drainage for intraductal papillary mucinous neoplasm infection

BMJ Case Reports ◽

10.1136/bcr-2021-242583 ◽

2021 ◽

Vol 14 (6) ◽

pp. e242583

Author(s):

Shunsuke Watanabe ◽

Masao Toki ◽

Junji Shibahara ◽

Tadakazu Hisamatsu

Keyword(s):

Intraductal Papillary Mucinous Neoplasm ◽

Cyst Wall ◽

Pancreatic Cyst ◽

Epigastric Pain ◽

Drainage Tube ◽

Endoscopic Drainage ◽

Endoscopic Retrograde Pancreatography ◽

Endoscopic Retrograde ◽

Mucinous Neoplasm ◽

Route Of Infection

A 61-year-old woman with intraductal papillary mucinous neoplasm (IPMN) infection, who was treated with antibiotics, developed IPMN reinfection with febrile epigastric pain and was febrile. CT showed that the diameter of the IPMN had grown and hardened, with thickening of the cyst wall. Endoscopic retrograde pancreatography was then performed and a nasopancreatic cyst drainage tube was placed into the cyst. Symptoms and inflammatory findings improved considerably 17 days after endoscopic drainage. Few reports and evidence have been found regarding IPMN infections, and the frequency of onset, route of infection and optimal drainage method remain unknown. This study indicated that endoscopic transpapillary pancreatic cyst drainage was effective and is highly recommended for IPMN infection.

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